KEGG   Ailuropoda melanoleuca (giant panda): 100470716
Entry
100470716         CDS       T01329                                 
Symbol
ATP2A1
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 1 isoform X1
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04020  Calcium signaling pathway
aml04022  cGMP-PKG signaling pathway
aml04024  cAMP signaling pathway
aml04148  Efferocytosis
aml04260  Cardiac muscle contraction
aml04261  Adrenergic signaling in cardiomyocytes
aml04380  Osteoclast differentiation
aml04919  Thyroid hormone signaling pathway
aml04972  Pancreatic secretion
aml05010  Alzheimer disease
aml05017  Spinocerebellar ataxia
aml05022  Pathways of neurodegeneration - multiple diseases
aml05410  Hypertrophic cardiomyopathy
aml05412  Arrhythmogenic right ventricular cardiomyopathy
aml05414  Dilated cardiomyopathy
aml05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    100470716 (ATP2A1)
   04024 cAMP signaling pathway
    100470716 (ATP2A1)
   04022 cGMP-PKG signaling pathway
    100470716 (ATP2A1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    100470716 (ATP2A1)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    100470716 (ATP2A1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    100470716 (ATP2A1)
   04261 Adrenergic signaling in cardiomyocytes
    100470716 (ATP2A1)
  09154 Digestive system
   04972 Pancreatic secretion
    100470716 (ATP2A1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    100470716 (ATP2A1)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    100470716 (ATP2A1)
   05017 Spinocerebellar ataxia
    100470716 (ATP2A1)
   05022 Pathways of neurodegeneration - multiple diseases
    100470716 (ATP2A1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    100470716 (ATP2A1)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    100470716 (ATP2A1)
   05414 Dilated cardiomyopathy
    100470716 (ATP2A1)
   05415 Diabetic cardiomyopathy
    100470716 (ATP2A1)
Enzymes [BR:aml01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     100470716 (ATP2A1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 100470716
NCBI-ProteinID: XP_002927374
Ensembl: ENSAMEG00000015582
Position
10:16995460..17013583
AA seq 999 aa
MEAAHSKTTEECLAYFGVSETTGLSPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETITAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIRSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVVATGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIVDKVDGNICVLNEFSITGSTYAPEGEVLKNDKPVRSGQYDGLVELATICALC
NDSALDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVKNLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPMTGPV
KDKIMSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSARFMEYETDLTFVGVVGMLD
PPRKEVTGSIELCRDAGIRVIMITGDNKGTAIAICRRIGIFGENEEVADLAYTGREFDDL
PLAEQREACRRARCFARVEPAHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG
SGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAAL
GLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAIG
GYVGAATVGAAAWWFLYADDGPHVTYSQLTHFMQCNEENPDFEGVDCEVFEAPEPMTMAL
SVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLQA
LDVTQWLMVLKISFPVIGLDEILKFVARNYLEDPEDERK
NT seq 3000 nt   +upstreamnt  +downstreamnt
atggaggctgcacactccaagaccacagaagaatgtttggcctattttggggtgagcgag
actacaggccttagcccggaccaagtgaagcggcatctggagaaatacggccccaacgag
ctccctgctgaagaagggaagtccctgtgggagttggtggtagagcagtttgaagacctc
ctggtgcggatccttctcctggccgcctgcatttccttcgtgctggcctggttcgaggaa
ggcgaagagaccatcactgcctttgtggaaccctttgtcatcctcttgatcctcattgcc
aatgccatcgtgggggtttggcaggagcgtaatgcagagaacgccatcgaggctctgaaa
gaatatgaacccgagatgggaaaagtttaccgggctgaccgcaagtcagtgcaaaggata
aaggctcgggacattgtccccggggacatcgtggaggtggccgtgggggacaaagtccct
gccgatatccgcatcctgtccatcagatccaccacgctccgggttgaccagtccatcctg
acaggcgagtccgtatctgtcatcaagcacacagaccctgtccctgacccccgagctgtc
aaccaggataagaagaacatgcttttctcgggtaccaacattgccgctggcaaggccttg
ggtattgtggttgccactggtgtgagcaccgagattgggaagatccgcgaccaaatggcc
gccacagaacaggacaaaacccccctgcagcagaagctggatgagtttggggagcagctc
tccaaggtcatctccctcatctgcgtggccgtctggctcatcaacatcggccacttcaac
gatcctgtgcacgggggctcctggttccgtggggccatatactactttaagatcgctgtg
gccctggctgtggccgcaatcccagaaggcctccctgccgtcatcaccacctgcctggcc
ctgggcacccggcggatggcaaagaaaaatgccatcgtgaggagcttgccctccgtagag
actctgggctgcacctctgtcatctgttcggacaagacgggcaccctcaccaccaaccag
atgtctgtctgcaagatgtttatcgtcgacaaagtggacggaaacatctgtgtcctgaac
gagttctccatcactggttccacttatgctccagaaggagaggtcctgaagaatgataag
ccagtccgctcagggcagtatgatgggctggtggagctggccaccatctgtgccctctgc
aatgactccgccttggacttcaatgagaccaaaggtgtttatgagaaggtgggcgaggcc
accgagaccgcactcaccaccctggtggagaagatgaatgtattcaacaccgaagtgaaa
aacctctccaaggtggagagggccaatgcctgcaactcggtgatccgccagctaatgaag
aaggaattcaccctggagttctcccgggacagaaagtccatgtcggtctactgctcccca
gccaaatcccgggctgctgtgggcaacaagatgtttgttaagggcgcccccgagggggtc
attgaccgctgtaactacgtgcgagttggcacaacccgggtgcccatgacggggccagtg
aaggataagatcatgtcggtgatcaaggagtggggcacgggccgggacacgctgcgctgc
ctggccctggccacccgggacacccccccgaagcgagaggagatggtcctggacgactct
gccaggttcatggagtacgagacggacctgacattcgttggcgtggtaggcatgctggat
cccccccgcaaggaggtcacaggctctattgagctgtgccgggacgccggaatccgagtc
atcatgatcacaggggacaacaagggcacagccattgccatctgccggcggatcggcatc
ttcggggagaatgaggaggtggccgacctagcctacacgggccgggagttcgacgacctg
cccctggccgagcagcgggaggcctgccgtcgcgcccgctgctttgcccgcgtggagccg
gcccataagtcgaagatcgtggagtatctgcagtcctacgatgagatcacggccatgact
ggcgatggggtcaatgacgcccccgccctgaagaaggccgagatcggcattgccatggga
tccggcaccgccgtggccaagacggcttctgagatggtgctggccgacgacaacttctcc
accatcgtggccgcggtggaggagggccgcgccatctacaacaacatgaagcagttcatc
cgctacctcatctcctccaacgtgggcgaggtggtctgcatcttcctgaccgccgcctta
gggctgcccgaggccctgatccccgtgcaactgctgtgggtgaacctggtgacggacggg
ctcccggccacggccctgggcttcaacccaccagacctggacatcatggaccggcccccc
cggagccccaaggagcccctcatcagtggctggctcttcttccgctacatggcaattggg
ggctacgtgggtgcagccactgtgggagcggctgcctggtggttcctgtatgcagacgac
gggcctcatgtcacctacagccagctgactcacttcatgcagtgcaacgaggaaaaccct
gacttcgagggcgtggactgtgaggtctttgaggcccccgagcccatgaccatggccttg
tccgtgctggttaccatcgagatgtgcaacgctctgaacagcctgtctgagaatcagtcc
ctcctgcggatgccgccctgggtaaacatctggctgctgggctccatctgcctctccatg
tccctccacttcctcatcctctacgtcgaccctctgccgatgatcttcaagctccaggcc
ctggacgtcacccagtggctcatggtcctcaagatctcatttccagtcattgggctcgac
gagatcctcaagttcgttgctcggaactacctggaggatccagaagatgaaaggaagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (18)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (3)   
   RefSeq(pep) (3)   
DNA sequence (4)   
   RefSeq(nuc) (4)   
Protein domain (7)   
   Pfam (7)   
All databases (52)   

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