KEGG   Acyrthosiphon pisum (pea aphid): 100168353
Entry
100168353         CDS       T01076                                 
Name
(RefSeq) epidermal growth factor receptor isoform X1
  KO
K04361  epidermal growth factor receptor [EC:2.7.10.1]
Organism
api  Acyrthosiphon pisum (pea aphid)
Pathway
api04013  MAPK signaling pathway - fly
api04068  FoxO signaling pathway
api04144  Endocytosis
api04214  Apoptosis - fly
api04320  Dorso-ventral axis formation
Brite
KEGG Orthology (KO) [BR:api00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04013 MAPK signaling pathway - fly
    100168353
   04068 FoxO signaling pathway
    100168353
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    100168353
  09143 Cell growth and death
   04214 Apoptosis - fly
    100168353
 09150 Organismal Systems
  09158 Development and regeneration
   04320 Dorso-ventral axis formation
    100168353
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:api01001]
    100168353
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:api04147]
    100168353
Enzymes [BR:api01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     100168353
Protein kinases [BR:api01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   100168353
Exosome [BR:api04147]
 Exosomal proteins
  Exosomal proteins of colorectal cancer cells
   100168353
  Exosomal proteins of pancreatic cancer cells
   100168353
  Exosomal proteins of bladder cancer cells
   100168353
Cytokine receptors [BR:api04050]
 Receptor tyrosine kinase
  RTK class I (EGF receptor family)
   100168353
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain Pkinase GF_recep_IV Furin-like Kinase-like Haspin_kinase MAP17 Fig1 DUF5367 DUF4381
Other DBs
NCBI-GeneID: 100168353
NCBI-ProteinID: XP_008184751
APHIDBASE: ACYPI009061
UniProt: A0A8R2B6W4
Position
A1:105309504..105394194
AA seq 1426 aa
MNAVFPSVFLRRLWRCRLLLVAVLVFHAATATAAAVEKTSEFVKGKICIGTNGRLSVPSN
RDHHYRNLRDRYTNCTYVDGNLELTWLQDEHLDLSFLQHIREVTGYVLITHVDVNKIVLP
RLQIIRGRTQFKLAVKEEEFSLLVMLSKMNNLELPALRDILAGNVGMIDNYNLCHMRTIN
WDEIITGSGAKWMYMYNFSNSERECPPCDKSCTGGCWGEGPHNCQKFSKINCSPQCYQGR
CFGPKPRDCCHLFCAGGCTGPKQSDCLACRNFYDDGVCTQECPAMQRYNSITYSWETNPN
GKYAYGATCVKNCPEHLLKDNGACVRSCPPKKKAVNGECVLCDGPCPKTCEGVTTIHDSN
IDGFKDCTVIEGSLTILDQTFKGFQQVFANFSFGQRIKAMNPDRLEVFSTLKEVTGYINI
QGSHEDFKNLSYFRNLEVIGGRTVTEYFASLYIVKTSLTSLGLRSLKKIHSGSVAILENK
RLCYAQTIDWESIKKSSEHPKLLQNNKNESLCILENEICDPECSKQGCWGPGPHQCLSCR
NFQYDNQCLPNCNHIPGLYEAGDKTCLACHPECNGGCHGPGPEHCTTCRNLLDGIHCVSQ
CPVNKYSANQTRPSECLPCHLNCVGGCSGPDNTIGPNGCRSCHKAVLNADASVERCLHKN
ETCPNGYYYEWVGPLEQGGAALRALAGKAVCRKCHPRCLRCTGFGFHDQVCQRCAGYKRG
DHCADDCPIEYYATTNKLPNGEIERECMPCDILCRGCYGPHASQCQACRHFKIFEPSGNP
SDNRTAFNCSGPICPSFAPYKVYTKDDPDPYCSADDVRMASKLSDSEQIPLILSAVVVFT
FLVMVLLMILVWHWRRRARAKETAVKMTMVLTGMEDNEPLRPSNVKPNTAKLRIVKEVDL
RIGAELGNGAFGVVYKGVWVVEGENIKIPVAIKKLHKKDDTCGYENTSKEFLDEAYIMAS
VEHDNLVKLLAVCMTSEMMLVTQLMPLGCLLKYVRNNNDKIGSKTFLKWCTQIAKGMAYL
EEKRLVHRDLAARNVLVQNTNCVKITDFGLAKLLEIDQLEYTADGGKMPVKWLAPECLKY
RVFTHKSDVWAFGITVWELLTYGKQPYESVDKKEVLGLLEKGERLPQPPICTIDVYMVMV
KCWLIEKDSRPSFEELADEFAKMAIDPGRYLVIPGDRYMRLPSYSSQDENEILSNLATEG
ADMSIMEADEYCMNPKMGNSMPGPSRLGSSSTAGADILGSMHGRHNWDRELRKFSDIHRL
DCDTSDDLSNGSKAQVGTLKLDLPLDEDDYLMPSPANDEIDNKRRHAPANYIDLIGHQHA
EAEYANGSLPRPPGLTKNFQPDFLPVQVSSVDNPEYHLTGGETSAVAPSTVSGDGSGSVE
ASCEPQSPAPTSNGRSLEDESDHEYYNDFDRLQRELQPLRRNETTV
NT seq 4281 nt   +upstreamnt  +downstreamnt
atgaatgcggttttcccgtccgttttcctccggcgactatggcggtgcaggctgttgcta
gttgccgtcctggtgttccacgcggccacggccaccgcggccgctgtcgagaaaacttca
gaattcgtcaaaggaaaaatatgtattggtaccaatggtcgtctgtccgtgccgtcgaat
cgggaccatcattaccggaacctcagggaccgttacaccaattgcacttatgtggatggc
aacctggaactgacgtggttgcaggacgaacacttggatctaagttttttacaacacata
cgagaagttaccggatacgttttgatcactcatgtggacgtcaacaaaatcgtgttgcct
cggctgcaaatcattcggggccgaactcaattcaaattggccgtcaaggaagaagagttt
tcgttactggtcatgttatcaaaaatgaacaatctggaattgccagctctcagagatata
ttggccggcaatgtgggcatgatcgataactataatctgtgccatatgcgcaccattaac
tgggatgagatcatcaccgggtcgggggccaagtggatgtacatgtataatttctcgaac
tctgaacgggaatgtccaccttgtgacaaatcatgtacgggtggttgttggggtgaaggt
cctcacaattgtcaaaagttctcaaagatcaactgtagtccccaatgttaccagggccgt
tgttttggaccgaagcccagagactgctgtcatttgttttgtgccggtggttgtacggga
ccaaagcaaagtgattgccttgcatgtcgaaatttctacgacgacggtgtatgcactcaa
gaatgtccggcgatgcaacgttataactccataacatactcctgggaaacaaatccaaat
ggaaagtatgcttatggcgcaacttgcgtaaaaaactgtccagaacatttgctcaaagac
aacggggcttgtgtgcgaagttgtccaccaaagaaaaaggctgtaaatggtgaatgtgtg
ttatgtgatggcccatgtccaaaaacttgtgaaggcgtaaccacgatacatgacagcaac
attgacggttttaaagactgtaccgtaatcgagggctcattaactatcttggatcaaaca
ttcaaaggtttccaacaagtttttgccaacttcagtttcggccaacgtatcaaagctatg
aatcctgatcgtttggaagtatttagcactttgaaagaagtaacaggctacataaacata
caaggatcacatgaagattttaaaaatctatcatactttaggaatttggaagttatcggt
ggtcgcactgttactgaatactttgcatcattgtatattgtaaagacttcgctaacttca
ttaggtttgcgttcactaaagaaaatccattctgggagcgttgcaatattagaaaataaa
agactgtgttacgcccaaactatagactgggagtccataaaaaaatcatcggaacatcca
aagctcttgcaaaataacaaaaatgaatctctttgcattttagagaatgaaatatgcgat
ccggagtgttcaaaacaaggttgctggggcccaggaccacatcagtgtttgtcttgtagg
aactttcagtacgataatcagtgtctaccgaactgtaatcatatacctgggctatacgag
gctggtgacaagacttgccttgcgtgtcatccggaatgtaatggtggttgtcatggaccc
ggtcccgaacactgtacaacatgccgcaatcttctcgacggtattcactgtgtgtctcaa
tgtccagtgaataaatacagcgctaaccaaaccagacccagtgagtgtttgccatgccat
ttgaactgtgttggaggttgtagtggtccggacaatacaattggacctaatgggtgtcga
tcttgtcacaaagctgttctcaatgctgatgcttcagttgagagatgtttacacaagaat
gaaacttgtccaaatggttactattacgaatgggttggaccgttggagcaaggtggtgct
gctctgcgtgcgttagccggcaaagctgtatgcagaaaatgtcatccacgatgtctgagg
tgcacaggtttcgggttccatgatcaagtctgccaacgttgcgcgggctacaaacgcggt
gatcactgcgcggacgattgtccaattgagtactatgccacgaccaacaaattgccgaat
ggagaaatagaacgagaatgtatgccatgtgacattctatgtagaggatgttacgggcca
catgcgtctcaatgccaggcgtgtaggcattttaaaatattcgagcccagtggtaaccct
tccgataaccgtacagcattcaactgctctggtcctatctgtccgtcttttgctccatac
aaggtatacaccaaggacgatccagacccatattgttccgctgatgacgttagaatggct
tctaaactaagtgattctgagcaaataccgttgatactaagcgcggttgtggtattcacg
tttttggtgatggttttactcatgattcttgtatggcactggcgaagacgcgcacgtgcc
aaagagacagcagtgaaaatgacaatggtactaacaggtatggaggataatgaaccacta
aggccttcaaacgtcaaacccaatacggccaaactaaggatcgtcaaagaagtagacctg
agaatcggcgctgaacttggaaatggagcttttggagtcgtgtacaagggcgtttgggtc
gttgaaggcgagaacattaaaataccagtagcaatcaaaaagctacacaaaaaagacgac
acgtgtggttatgagaatactagcaaagaatttttggatgaagcttatataatggctagc
gtcgagcacgacaatctagtaaaactgttagccgtatgtatgacatccgaaatgatgttg
gtcacccaactcatgccactcgggtgcttgttgaagtacgtgcgaaataataatgacaag
atcggttcgaaaacgttcctaaaatggtgtacgcaaatagccaaaggtatggcatatttg
gaagaaaaacgactggtgcacagggatctggcagcccgaaacgtgctcgtgcagaacacc
aactgcgtgaagattaccgattttggtttggctaaactgttggaaatcgaccaactggag
tacactgccgacggtggaaagatgcctgtgaaatggctagcgccagaatgtcttaagtac
agggtgttcacccacaaaagcgatgtctgggcgtttggtatcaccgtgtgggaattgttg
acttacggtaaacaaccgtatgaaagcgtggacaagaaagaagttttaggtctgctagaa
aaaggtgaacgattaccacaaccgcccatttgcaccattgatgtttacatggtgatggtc
aagtgttggctgatcgaaaaagatagccgtcctagttttgaggaactcgccgacgaattt
gccaaaatggcaatcgatcctggtagatacctggtcataccgggtgaccgttacatgaga
ttgccgtcgtactcgtcgcaggacgaaaacgagatactatcgaacttggcgactgaaggt
gcggatatgagtatcatggaagctgacgagtactgcatgaacccaaagatgggcaacagc
atgccgggaccatcgagactgggatcgagtagcacagcgggtgctgacattctaggatct
atgcatggtagacacaactgggatcgcgagctcagaaaattcagtgacatacatcgatta
gattgcgatacttccgacgatcttagtaatggaagcaaggcgcaagtgggcacgttgaaa
ttagacttgcccttggacgaggacgattacttaatgccgtccccagcaaatgacgaaatc
gacaacaagcgtcggcacgcgcctgccaactatatcgatttgattggtcaccaacacgct
gaagcggaatatgccaatggtagcctaccgaggcctccaggtctgacgaaaaacttccaa
ccagacttcttgccagtccaggtgagcagcgtggacaacccggagtaccatttgaccggt
ggtgaaacttccgccgtggctccatctacagtctccggcgacggtagtggttctgtggag
gcgtcctgcgaaccacagtcacccgcgcctacctccaacggccgcagtctggaggacgag
tcggaccatgagtactacaacgactttgatcgactgcagagagagctccaaccgctcaga
cgaaacgaaacgaccgtttga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (137)   
   KEGG ORTHOLOGY (1)   
   RefGene (132)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   APHIDBASE (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (12)   
   RefSeq(nuc) (4)   
   GenBank (4)   
   EMBL (4)   
Protein domain (11)   
   Pfam (11)   
All databases (176)   

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