KEGG   Actinoplanes sp. SE50/110: ACPL_8124
Entry
ACPL_8124         CDS       T02044                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
ase  Actinoplanes sp. SE50/110
Pathway
ase00290  Valine, leucine and isoleucine biosynthesis
ase00620  Pyruvate metabolism
ase01100  Metabolic pathways
ase01110  Biosynthesis of secondary metabolites
ase01210  2-Oxocarboxylic acid metabolism
ase01230  Biosynthesis of amino acids
Module
ase_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:ase00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    ACPL_8124 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    ACPL_8124 (leuA)
Enzymes [BR:ase01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     ACPL_8124 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer
Other DBs
NCBI-ProteinID: AEV89002
UniProt: G8SCC6
Position
8952674..8954401
AA seq 575 aa
MSTFAENSQRSSSMPFQRYESYQKQFAIDLPDRRWPGRVVEQTPRWCAVDLRDGNQALID
PMSPERKRRMFMLLVKMGYKEIEVGFPAASQTDFDFVRQLIEQDLIPDDVTIQVLVQCRE
HLIDRTFESIRGAKRAIVHFYNSTSVLQRRVVFGLDRDGITDIATQGARLCQKYAEIHTP
DTEIFYEYSPESYTGTELEYALEVCSAVIDVIDPTPARPLIINLPATVEMATPNVYADSI
EWMHRHLPRRDSVILSLHPHNDRGTAVAAAELGLLAGADRIEGCLFGNGERTGNVDLVTL
GLNLFSQGIDPQIDFADIDEVKRTVEYCNQLPVHERHPYAGDLVYTAFSGSHQDAIKKGF
AALQADADAAGTPIDDFTWGVPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKEEHKL
DMPRRLQIEFSGVVQHHTDEEGGEVSPQQMWDIFAQEYLVEHQLGSAFKIESYSTATVDG
KVEIDVEVIHRGMRRPLVGVGNGPIDAFTQAVAPLGIKARVLDYQEHALTSGGDAQAAAY
VEVEVGDRAFWGVGIDANIVSASIKAVNSAINRAR
NT seq 1728 nt   +upstreamnt  +downstreamnt
atgtccaccttcgccgagaattcgcagcgttccagctcgatgcccttccagcggtacgag
tcctatcagaaacagttcgcgatcgatctgcccgaccggcggtggcccggccgcgtcgtc
gagcagaccccccgctggtgcgccgtcgacctgcgggacggcaatcaggcgctgatcgac
ccgatgtccccggaacgcaagcggcggatgttcatgctgctggtgaagatgggctacaag
gagatcgaggtcggcttcccggccgccagccagaccgatttcgacttcgtccgccagctg
atcgagcaggacctgatcccggacgacgtcaccatccaggtgctggtgcagtgtcgcgag
cacctgatcgaccggaccttcgagtcgatccgcggtgccaagcgggccatcgtgcacttc
tacaactcgacctcggtgctgcagcgccgcgtggtcttcggcctggaccgggacgggatc
accgacatcgccacccagggcgcccggctctgccagaagtacgccgagatccacaccccg
gacaccgagatcttctacgagtactccccggagtcgtacaccggcaccgagctggagtac
gcgctggaggtctgctccgcggtgatcgacgtgatcgacccgacgccggcccggccgctg
atcatcaacctgccggccaccgtcgagatggccacgcccaacgtgtacgccgattcgatc
gagtggatgcaccgccacctgccgcgccgggacagcgtgatcctgagcctgcacccgcac
aacgaccggggtaccgcggtggccgccgccgagctgggcctgctggccggcgccgaccgg
atcgagggctgcctgttcggcaacggtgagcgcaccggcaacgtggacctggtcaccctg
gggctgaacctgttctcccagggcatcgacccgcagatcgacttcgccgacatcgacgag
gtcaagcgcaccgtcgagtactgcaaccagctgccggtgcacgagcggcacccgtacgcg
ggcgacctggtctacaccgcgttctccggctcgcaccaggacgcgatcaagaagggtttc
gccgcgctgcaggcggacgcggacgccgccggcaccccgatcgacgacttcacctggggc
gtgccctacctgccgatcgacccgaaggacgtgggccgcacgtacgaggcggtcatccgg
gtcaactcgcagtccggcaagggcggcgtggcgtacatcatgaaggaggagcacaagctc
gacatgccgcggcggctgcagatcgagttctccggcgtggtgcagcaccacaccgacgag
gagggcggcgaggtctccccgcagcagatgtgggacatcttcgcgcaggaatacctggtc
gagcaccagctgggcagcgccttcaagatcgagagctacagcacggccaccgtggacggc
aaggtggagatcgacgtcgaggtgatccaccgggggatgcggcggccgctggtcggcgtc
ggcaacggcccgatcgacgcgttcacccaggcggtcgcgccgctcgggatcaaggcccgg
gtgctggactaccaggagcacgcgctgacctccggcggtgacgcccaggccgcggcgtac
gtcgaggtcgaggtcggcgaccgcgccttctggggggtcggtatcgacgccaacatcgtc
agcgcgtcgatcaaggcggtgaacagcgcgatcaaccgcgcccgctag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (23)   

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