KEGG   Candidatus Bathyarchaeota archaeon BA2: AOA66_0681
Entry
AOA66_0681        CDS       T04066                                 
Symbol
leuA_2
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
barb  Candidatus Bathyarchaeota archaeon BA2
Pathway
barb00290  Valine, leucine and isoleucine biosynthesis
barb00620  Pyruvate metabolism
barb01100  Metabolic pathways
barb01110  Biosynthesis of secondary metabolites
barb01210  2-Oxocarboxylic acid metabolism
barb01230  Biosynthesis of amino acids
Module
barb_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:barb00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    AOA66_0681 (leuA_2)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    AOA66_0681 (leuA_2)
Enzymes [BR:barb01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     AOA66_0681 (leuA_2)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer DUF561 EF-hand_14
Other DBs
NCBI-ProteinID: KPV63725
UniProt: A0A0N8PWE8
AA seq 507 aa
MKSKNVKYVSIFDTTLRDGEQTPGVSLTTEEKLEIARQLDRLGVDVIEAGTPISSEGEKR
AVREITKAGLNAEICALARTTRVDVDAAIACDVGSVHTFISTSDVQMKHAVNMTPEQVLS
ATIDSVEYIKDHGLICEFSPMDATRTEINFLKRVCKAAEEAGADRINIPDTVGIMTPVTM
RKLIEDVKSVVGVPISVHCHNDFGMAVANSLAGVEAGASQIHVTVNGLGERAGNAALEEV
VMALHLIYNRKTGINTKLLYDTSRLVAKLTGVMIQPNKAIVGENAFAHESGIHTRGVTVV
PLTFEPIKPELVGRKRKLVAGKLSGTSGIKAELKEAGIYPNKDQLGEIVRRVKELGDKGK
TVTDADLLAITRSVMGKVVKEKRIVDLTDLAVVTGIRVIPTASVRLVLDGKEYVTSETGL
GPVDAAIKAVQKLTADLAEVRLKEYRIEATTGGSDAMGEVIIKVEDRDGNVVSARATHED
IVMASVEAMINAINKSLLKRRNRDKQA
NT seq 1524 nt   +upstreamnt  +downstreamnt
atgaaatcgaaaaatgtgaaatacgtaagcatctttgacacgacgcttagagacggagaa
caaaccccgggagtgtcgctaaccacagaggaaaaattggaaatagcacgccaacttgac
aggttgggtgtagacgttatagaagctggcaccccaataagctcggaaggcgagaaaaga
gcagtcagagaaataactaaagctggactgaacgctgaaatatgcgccctcgctcgcacc
acaagggtagacgtcgacgcggccatcgcctgtgatgtcggctcggttcacacctttata
tcaacttcagatgtacaaatgaaacacgccgtaaacatgacccctgaacaagttttgtcc
gcaaccattgattccgtagagtacattaaagaccatggattgatatgcgagttttcaccc
atggacgccacgagaacagagataaatttcctgaagcgagtgtgcaaagctgctgaggag
gctggagccgaccgaataaatattccggataccgttggaataatgacccctgtaaccatg
cgaaaacttattgaggatgttaaaagcgtggtgggagtccccatcagtgtacattgccat
aacgacttcggaatggcagttgccaactccctggctggagttgaggcaggggcttctcaa
attcacgtaaccgtgaacgggctgggtgaaagagctggaaacgcggcactagaggaagtt
gtaatggcccttcatctaatttataaccgaaaaacagggataaacactaagctactctac
gacacttcacgactggtggctaaattaacgggcgttatgatacagcccaataaggctatc
gtaggtgaaaacgcctttgcccatgagtccggtatacacacccgcggagtcaccgtggtt
cccttaaccttcgagccaataaagccagagctcgtgggaagaaaaaggaagcttgtggct
ggcaaactgtccggtaccagcggcatcaaagcggagttgaaagaggctggaatctatcct
aacaaagatcaattgggagagattgttagaagggttaaagagttgggagacaagggtaaa
acagtgacagacgccgatctgttagccataaccagatcagttatgggaaaagtggtgaag
gaaaagagaatcgtcgacttaaccgacctggcggtagtaacgggaatcagagttattcca
acagcctctgtgagacttgtgttagatggaaaggagtacgtcacttcggaaactggttta
ggtccagtggacgccgccatcaaggctgtgcaaaagcttacagccgacctagcggaagtt
aggttaaaggagtatcggatagaggctacaactgggggctcagacgccatgggtgaagtg
ataataaaagttgaggacagagatggaaacgttgtctcggcaagggctacccatgaagac
atagtcatggctagtgttgaggcaatgataaatgcgattaacaaaagtctgctgaagaga
agaaaccgggacaaacaggcttga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (14)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (4)   
   Pfam (4)   
All databases (36)   

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