KEGG   Bifidobacterium breve ACS-071-V-Sch8b: HMPREF9228_0185
Entry
HMPREF9228_0185   CDS       T01844                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
bbv  Bifidobacterium breve ACS-071-V-Sch8b
Pathway
bbv00290  Valine, leucine and isoleucine biosynthesis
bbv00620  Pyruvate metabolism
bbv01100  Metabolic pathways
bbv01110  Biosynthesis of secondary metabolites
bbv01210  2-Oxocarboxylic acid metabolism
bbv01230  Biosynthesis of amino acids
Module
bbv_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:bbv00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    HMPREF9228_0185 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    HMPREF9228_0185 (leuA)
Enzymes [BR:bbv01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     HMPREF9228_0185 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer CATIP_N DUF4953
Other DBs
NCBI-ProteinID: AEF26581
Position
230777..232693
AA seq 638 aa
MGQDQSSVFDLAAVAAASNGGNNDPLLPPARFIGDSQKPSRMPYNKYASYSEQIPFDYPE
RTWPGKRLQRAPRWCSVDLRDGNQALVNPMDSERKLRFWNLLVSMGFKEIEVGFPSASET
DFDFIRMLIERELIPDDVTIVVLTQCREHLIRRTYEALKGAKRAIVHFYNSVSVLQREVV
FKKNKEEIKKLATDAAELCKDLESEAKGIDLYYEYSPESFTGTEPEYAVEVCNAVIGVIK
PTPEHPMIINLPATVEMTTPNVFADEVEYVSTHLDDRDSVVLSLHPHNDEGMGVAATELA
VLAGADRVEGCLLGNGERTGNVDLVTLGLNWLTQGIDPQLDLSNVPEIRKTVEYCNQIKI
SERHPYAGNFVFTAFSGSHQDAIKKGLEARQVAAERAGADLDSFVWLVPYLPIDPKDIGR
TYEAIIRVNSQSGKGGMAYLLKTNHNLDLPKRLQIEFDKIVQNFADTTKKEVKDEDIWRL
FKDEYLPVEQSGMTAAGVVVGDTHDASLAPWGRLKLLKVSVSSGEDGSDTVLKARLLDRG
VNVGGEQPVEREVSGIGNGPIAAFLNAISNFGVDASIMDYVEHTMSVGTDAMAASYVECQ
VGEADDAQIVWGVGIDSSITTSALKAIISAINRSQRNR
NT seq 1917 nt   +upstreamnt  +downstreamnt
atgggtcaggatcaatcgtccgtgtttgatctcgcggccgtggccgcggcgtccaatggg
gggaacaacgacccgctgctgcctccggcacgattcatcggcgattcgcagaagcccagc
cgtatgccgtacaacaagtacgcctcatacagcgagcagatcccgtttgattacccggag
cgcacgtggccgggtaagcgactgcagcgcgcaccgcgctggtgctccgtcgatcttcgc
gacggcaaccaggccctcgtcaacccgatggattccgagcgcaagctgcgcttctggaac
ctgctcgtctccatgggattcaaggagatcgaggtgggcttcccgtccgcatccgaaacc
gatttcgacttcatccgcatgctcatcgagcgcgagctcatcccggacgatgtgactatc
gtggtgctcacccagtgccgcgagcacctcatccgccgcacctacgaggcgctcaagggc
gccaagcgcgccatcgtgcacttctacaactccgtgtccgtgctgcagcgcgaagtggtg
ttcaagaagaacaaggaagagatcaagaaactcgccaccgatgccgctgaactatgcaag
gacctcgaatccgaggccaagggcatcgacctgtactacgagtactcgccggaatccttc
accggaaccgagccggagtacgccgtcgaggtgtgcaacgccgtgatcggcgtcatcaag
cccacccccgagcatccgatgatcatcaatctgcccgccaccgtggaaatgaccacgccg
aacgtgttcgccgacgaagtggagtacgtctccacccacctcgacgaccgtgattccgtg
gtgctctccctccacccgcacaacgacgaaggcatgggcgtggccgccaccgagctggcc
gtgctggccggcgccgaccgcgtggaaggctgcctgctgggcaacggtgagcgcaccggc
aacgttgacctggtcacgctgggcctcaactggctcacccagggcatcgacccgcaactc
gacctgtccaacgtacctgagatccgcaagacggttgagtactgcaaccagatcaagatt
tccgagcgccatccgtacgccggcaacttcgtgttcaccgcgttctccggctcgcatcag
gacgccatcaagaagggtctcgaggcccgtcaggtggccgccgagcgcgccggcgccgat
ctcgacagcttcgtctggctcgtgccctacctgccgatcgatccgaaggacatcggccgc
acctacgaggccatcatccgcgtcaactcgcagtccggcaagggcggcatggcatacctg
ctcaagaccaaccacaaccttgacctgccgaagcgcctgcagatcgaattcgacaagatc
gttcagaacttcgccgacaccaccaagaaggaagtcaaggacgaggacatctggcgcttg
ttcaaggatgagtacctgccggtcgaacagtctggcatgaccgccgccggcgtggttgtg
ggcgatacccacgacgcttcgcttgcgccttggggccgcctgaagctgctcaaggtgtcc
gtcagctccggtgaggacggttccgacaccgtgctcaaggctcgcctgctcgaccgcggc
gtgaacgttgggggcgagcagcccgtggagcgcgaggtgtccggcatcggcaacggtccg
atcgccgccttcctcaacgccatctccaacttcggcgtggacgcctcgattatggactat
gtggagcacaccatgtccgtgggtaccgacgccatggccgcctcctatgtggaatgccag
gtcggtgaggctgacgacgcgcagatcgtgtggggcgtgggcattgactcgtccattacc
accagcgcgctgaaggcgattatctccgccatcaaccgttcccagcgcaaccgctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (4)   
   Pfam (4)   
All databases (24)   

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