KEGG   Burkholderia mallei NCTC 10247: BM44_1649
Entry
BM44_1649         CDS       T03524                                 
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
  KO
K00163  pyruvate dehydrogenase E1 component [EC:1.2.4.1]
Organism
bmaz  Burkholderia mallei NCTC 10247
Pathway
bmaz00010  Glycolysis / Gluconeogenesis
bmaz00020  Citrate cycle (TCA cycle)
bmaz00620  Pyruvate metabolism
bmaz00785  Lipoic acid metabolism
bmaz01100  Metabolic pathways
bmaz01110  Biosynthesis of secondary metabolites
bmaz01120  Microbial metabolism in diverse environments
bmaz01200  Carbon metabolism
bmaz01210  2-Oxocarboxylic acid metabolism
Module
bmaz_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:bmaz00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    BM44_1649 (aceE)
   00020 Citrate cycle (TCA cycle)
    BM44_1649 (aceE)
   00620 Pyruvate metabolism
    BM44_1649 (aceE)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    BM44_1649 (aceE)
Enzymes [BR:bmaz01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     BM44_1649 (aceE)
SSDB
Motif
Pfam: PDH_E1_M Transketolase_N Transketolase_C
Other DBs
NCBI-ProteinID: AIS29486
Position
1:1821893..1824589
AA seq 898 aa
MSAVPNEVMKYVAAERDDDAQETVEWLEALDGVISSVGPGRAHYLIEKQIEFARMHGEHL
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNAIAMVLRAGKHTNVGGHIASFAS
AATLYDVGYNHFWHAPSAEHGGDLVFVQGHSSPGIYSRAFLLGRLTEDQLDNFRQEVGGN
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLQARGIVKTEGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
IWGSRWDALFARDKTGALMRRMMEAVDGEYQTYKSESGAYVREHFFNTPELKALVADWSD
DDIWNLNRGGHDPHKIYAAFHEASNSKGAPTVILAKTIKGYGMGEAGQAMNITHQQKKLP
VEQLKKFRDQFRLPIADDVIADVPYLKFDEGSKELEYMRAHRQALGGYLPQRRQKAQSLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
RQIGIWNQEGQKYVPEDSDQLMFYKESETGQILQEGINEAGGMCDWIAAATSYSTHGEIM
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLMWAASV
PNCVSYDPTFGYELAVIVQDGLRRMVQEQEDVYYYVTVMNENYEHPAIPQGEHVAADIIK
GMYAFRKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
DVERWNLLHPAEARRLSHVQTCLKDTQGPVIASTDYVRALADQIRGQIDRRYVVLGTDGF
GRSDTRGALRHFFEVDRYWVTVAALNALADEGTIERKVVADAIAKYNLDPAKPNPMTV
NT seq 2697 nt   +upstreamnt  +downstreamnt
atgtccgctgtaccgaatgaagtgatgaagtacgtcgcagccgaacgcgacgacgacgcg
caggaaaccgtcgaatggctcgaagcgctcgacggcgtgatttcgtcggtcggccccggc
cgcgcgcactacctgatcgaaaagcagatcgaattcgcgcgcatgcacggcgagcacttg
ccgttctccgcgaacaccccgtacatcaacacgattcccgtcgaagcccaggcgaagatt
ccgggcgaccaggacatcgagcaccggatccgctcgtacacgcgctggaacgcgatcgcg
atggtgctgcgcgcgggcaagcacacgaacgtcggcggccacatcgcgtcgttcgcttcg
gccgcgacgctctatgacgtcggctacaaccacttctggcacgcgccgtccgccgagcac
ggcggcgatctcgtgttcgtgcagggccactcgtcgcccggcatttattcgcgcgcgttc
ctgctcggccgcctgacggaagatcagctcgacaacttccgccaggaagtgggcggcaac
ggcatctcgtcgtatccgcacccgtggctgatgccggatttctggcagttcccgaccgtg
tcgatgggcctcggtcccatcatggcgatctatcaggcgcgcttcatgaagtacctgcag
gcgcgcgggatcgtgaagacggaaggccgcaaggtctgggcgttcctcggcgacggcgag
accgacgagccggaatcgctcggcgcgatcggcatggcgagccgcgagaagctcgataac
ctcgtgttcgtgatcaactgcaacctgcagcgtctcgacggcccggtgcgcggcaacggc
aagatcatccaggagctcgaatcggagttccgcggcgccggctggaacgtgatcaaggtg
atctggggcagccgctgggatgcgctgttcgcgcgcgacaagacgggcgcgctgatgcgc
cggatgatggaagccgtcgacggcgagtatcagacgtacaagtcggagtcgggcgcgtac
gtgcgcgagcacttcttcaacacgccggagctgaaggcgctcgtcgccgactggtccgac
gacgacatctggaacctgaaccgcggcggccacgatccgcacaagatctacgcggcgttc
cacgaggcgagcaattcgaagggcgcgccgacggtgatcctcgcgaagacgatcaagggc
tacgggatgggcgaagccggccaggcgatgaacatcacgcaccagcagaagaagttgccc
gtcgagcaactgaagaagttccgcgaccagttccgcctgccgatcgccgacgacgtgatc
gccgacgtgccgtacctgaagttcgacgaaggctcgaaggaactcgagtacatgcgcgcg
caccgccaggcgctcggcggctatctgccgcagcgccgccagaaggcgcaatcgctgccg
gtgccggcgctcgacgcgttcgagccgctgctcaagggcacgggcgaaggccgcgagatc
tcgacgacgatggcgttcgtgcggatcctgaacatcctgctgaaggacaaggcgctcggc
aagcgcgtcgtgccgatcgtgccggacgaatcgcgcacgttcggcatggagggcctgttc
cgccagatcggcatctggaaccaggaaggccagaagtatgtgccggaagattccgatcaa
ctgatgttctacaaggaatcggaaaccggccagatcctgcaggaaggcatcaacgaagcg
ggcggcatgtgcgactggatcgcggcggcgacgtcgtactcgacgcacggcgagatcatg
gtgccgttctatatcttctattcgatgttcggcttccagcgcatcggcgatctcgcgtgg
gcggcgggcgacatgcgctcgcgcggtttcctgctcggcggcaccgcgggccgcacgacg
ctcaacggcgaaggcctgcagcacgaagacggccactcgctgatgtgggcggcttcggtg
ccgaactgcgtgagctacgatccgacgttcggctacgagctcgccgtcatcgtgcaggac
ggcctgcgccggatggtgcaggagcaggaggacgtctactactacgtgacggtgatgaac
gagaactacgagcacccggcgattccgcagggcgagcacgtggcggccgacatcatcaag
ggcatgtacgcgttcaggaaagccgacgccgacaagaaggcgccgcgcgtgcaactgctc
ggcgcgggcacgatcttcaacgaagtgatcgccgcggcggacctgctgaagaacgactgg
ggcgtcgccgccgatctctggagcgtgccgagcttcaccgagctcgcgcgcgaaggccat
gacgtcgagcgctggaacctgctgcatccggccgaggcgcgccgcctgtcgcacgtgcag
acgtgcctgaaggacacgcagggcccggtgatcgcgtcgaccgactacgtccgcgcgctc
gccgaccagatccgcggccagatcgaccgccgctacgtcgtgctcggcaccgacggcttc
ggccgctcggacacgcgcggcgcgctgcgccacttcttcgaggtggaccgctactgggtc
acggtcgcggcgctcaacgcgctcgccgatgaaggcacgatcgagcgcaaggtcgtcgcc
gacgccatcgcgaagtacaacctcgacccggccaagcccaacccgatgacggtttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

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