KEGG   Bos mutus (wild yak): 102276849
Entry
102276849         CDS       T02919                                 
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5
  KO
K04426  mitogen-activated protein kinase kinase kinase 5 [EC:2.7.11.25]
Organism
bom  Bos mutus (wild yak)
Pathway
bom01524  Platinum drug resistance
bom04010  MAPK signaling pathway
bom04071  Sphingolipid signaling pathway
bom04141  Protein processing in endoplasmic reticulum
bom04210  Apoptosis
bom04530  Tight junction
bom04668  TNF signaling pathway
bom04714  Thermogenesis
bom04722  Neurotrophin signaling pathway
bom04932  Non-alcoholic fatty liver disease
bom04936  Alcoholic liver disease
bom05010  Alzheimer disease
bom05012  Parkinson disease
bom05014  Amyotrophic lateral sclerosis
bom05016  Huntington disease
bom05017  Spinocerebellar ataxia
bom05022  Pathways of neurodegeneration - multiple diseases
bom05208  Chemical carcinogenesis - reactive oxygen species
bom05417  Lipid and atherosclerosis
bom05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bom00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    102276849 (MAP3K5)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    102276849 (MAP3K5)
   04668 TNF signaling pathway
    102276849 (MAP3K5)
   04071 Sphingolipid signaling pathway
    102276849 (MAP3K5)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    102276849 (MAP3K5)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    102276849 (MAP3K5)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    102276849 (MAP3K5)
  09159 Environmental adaptation
   04714 Thermogenesis
    102276849 (MAP3K5)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    102276849 (MAP3K5)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    102276849 (MAP3K5)
   05012 Parkinson disease
    102276849 (MAP3K5)
   05014 Amyotrophic lateral sclerosis
    102276849 (MAP3K5)
   05016 Huntington disease
    102276849 (MAP3K5)
   05017 Spinocerebellar ataxia
    102276849 (MAP3K5)
   05022 Pathways of neurodegeneration - multiple diseases
    102276849 (MAP3K5)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    102276849 (MAP3K5)
   05418 Fluid shear stress and atherosclerosis
    102276849 (MAP3K5)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    102276849 (MAP3K5)
   04932 Non-alcoholic fatty liver disease
    102276849 (MAP3K5)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    102276849 (MAP3K5)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:bom01001]
    102276849 (MAP3K5)
Enzymes [BR:bom01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     102276849 (MAP3K5)
Protein kinases [BR:bom01001]
 Serine/threonine kinases: STE group
  STE11 family
   102276849 (MAP3K5)
SSDB
Motif
Pfam: MAP3K_TRAF_bd Pkinase HisK-N-like PK_Tyr_Ser-Thr ASK_PH TPR-S DRHyd-ASK FPP Kinase-like Pkinase_fungal
Other DBs
NCBI-GeneID: 102276849
NCBI-ProteinID: XP_005899163
Position
Un
AA seq 1438 aa
MGPDSIAELGRHRPEEGAVVTGNVARASWRWLRRPEYSQERLFLGPSYSRVRSGLLPTPG
YLGWGAQWVTEENLGLARCSGLGCGPGAATRSVSSGLELPSSALPRGGPRLSVPRRVGGK
KPVADLPGAGCPSATSGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVVAESEALQCL
REACETVGAALETLHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFS
MANNIILYCDTNSDSLQSLKEIICQKNTMCTGNYTFIPYMITPHSKVYCCDSSFMKGLTE
LMQPNFELLLGPICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAEL
ARIRQRVDNIEVLTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYA
FALNRRNLPGDRAKALDIMIPLVQNEEQVASDMYCLVGRIYKDMFLDSNFMDTESRDHGA
SWFKKAFESEPTLQSGINYAVLLLASGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYW
EVGFFLGASVLANDHLRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTSEQPVAKQ
ELVDFWMDFLVEATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDK
KGIHEWNFSASSVRGVSVSKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEE
KGKNTEEGDCEGDSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDS
RYSQPLHEEIALHKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDN
EQTIGFYTKQILEGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCT
ETFTGTLQYMAPEIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGM
FKVHPEIPESMSAEAKAFILKCFEPDPDKRDCANDLLMDEFLKVSSKKKKTQPKLSALSA
GSNEYLRSISLPVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGEKDVKGIRTL
FLGIPDENFEDHSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQG
AEEPKLKWEHITTLVASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQD
AVNKVLRNHNIKPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEG
DHDERPSNQTVRRPHAVLEDAVATSGVSTLSSTVSHDSQSAHRSLNVQLGRMKIETNRLL
EELVQKEKELQALLHQAIEEKDQEIKHLKLKSQPIDVPGLPGCHSSSPGTNTEDSELTDW
LRENGADEDTISRFLAEDYSLMDVLYYVTRDDLKCLRLRGGMLCTLWKAITDFRDKQA
NT seq 4317 nt   +upstreamnt  +downstreamnt
atgggacccgacagcatcgcggagctaggccggcaccggccggaggagggcgccgtggtt
acggggaacgtggcgcgtgcctcctggcgctggctgagaagacccgagtattcgcaagag
agactttttttggggccatcctatagtcgcgtgcgctccgggcttttgcctactccaggt
tatcttgggtggggagcccagtgggtgacggaggagaaccttggcctcgcgcggtgctcc
gggctgggctgcggtccgggagccgcgacgcggtcggtttcgtccggactcgagcttccc
agcagcgccctcccccggggcgggcccagactttcagtgccgcgacgagtgggcggcaaa
aagccggtggcggacctgcccggcgccgggtgtcccagtgccacctccgggagcagcgcc
acccggtgccggggcaactctgggggcggaggcggccgacggaccacggtggcctatgtc
atcaacgaggcgagccaggggcagctggtggtggccgagagcgaggccctgcagtgcctg
cgggaggcgtgcgagacggtgggcgccgccctggagaccctgcattttgggaaactggac
tttggggaaactgcggtgctggaccgattttacaatgcagatatcgccgtggtggagatg
agtgatgccttccgacaaccatccttattttaccaccttggagtgagagaaagtttcagc
atggccaacaacatcatcctctactgtgatactaattcagactctctgcagtcgctgaag
gagatcatttgccagaagaatactatgtgcactggaaactacacgtttatcccttacatg
ataacgccgcacagcaaggtctactgctgtgacagcagcttcatgaagggcttgactgag
ctcatgcagccaaactttgagctgcttctgggacccatctgcttacctctcgtggatcgt
ttcattcagcttttgaaggtggcacaagcaagttccagccagtatttccgggagtctata
ctcaacgatatcaggaaagctcgtaacttatatactggcaaagaattggcagctgaattg
gcaagaattcgacagcgagtggataatattgaagtcttgacagcagatattgtcataaat
ctgttactttcatatagagatatccaggactatgattctattgtgaagctggtagagact
ttagaaaagcttccaacgtttgatttggcctcccatcaccatgtgaagtttcattatgcc
tttgcactgaataggagaaacctccctggagatagagcaaaagctcttgacattatgatt
cccctggtgcaaaatgaagagcaggttgcttcagatatgtattgcctcgttggtcgaatc
tacaaagatatgtttttggactctaatttcatggacactgaaagcagagaccatggagct
tcttggttcaaaaaggcatttgaatcagagccaacactacagtcaggaattaattatgcg
gtcctcctcctggcatctgggcaccagtttgaatcttcctttgagctccgaaaagttggg
gtgaagctaagcagtcttcttggtaaaaagggaaacttggaaaaactccagagctactgg
gaagttggatttttcctgggggccagtgtcctggccaatgaccacttgagagtcattcaa
gcatctgaaaagctttttaaactgaagacacctgcatggtacctcaagtctatcgtagag
acaattttgatatataagcattttgtgaaactgacttcggaacagcctgtggccaaacag
gaacttgtggacttctggatggatttcctggtcgaggccacaaagacagatgtcactgta
gttaggtttccagtattaatattagaaccaaccaaaatctatcaaccttcgtatttgtct
atcaacaatgaagttgaggagaagacaatatctatttggcacgtgcttcctgatgacaag
aaaggtatacatgagtggaattttagtgcttcttctgtcaggggtgtgagtgtttctaaa
tttgaagaacgatgctgttttctgtatgtgcttcacaattctgacgatttccaaatctac
ttctgtacagaacttcactgtaaaaagttttttgaaatggtgaacaccattactgaagag
aaggggaaaaacacagaggaaggagattgtgaaggtgactccctggagtatgactatgaa
tacgatgaaaatggtgacagagtcgtattaggaaaaggcacttatgggatagtttatgca
ggtcgagatctgagcaaccaagtcagaatcgccattaaggaaatcccagagagagacagc
agatactcccagcccctgcatgaagaaatagccttgcataagcatctgaagcacaaaaat
attgtccagtatctgggctctttcagtgaaaacggtttcattaaaatcttcatggagcag
gtcccaggaggaagtctttctgctctccttcgttccaaatggggcccactgaaagacaat
gagcaaacaattggcttttatacaaagcaaatactggaaggattaaaatacctccatgat
aatcagatagttcaccgggatataaagggtgacaatgtgttgattaatacctacagcggt
gttctcaagatttctgatttcggaacatcaaagaggcttgctggcataaatccatgtact
gaaacttttactggtaccctccagtatatggcaccagaaataatagataaaggaccaaga
ggctatggaaaggcagcagacatttggtctctgggctgcacgatcattgaaatggccact
ggaaaaccacccttttatgaactgggggaaccacaagcagctatgttcaaggtggggatg
tttaaagtccacccagagatcccagagtccatgtcagcagaggccaaggcgttcatattg
aagtgttttgaaccagaccctgacaagagagactgtgctaacgacttgcttatggatgag
ttcttaaaagtttcaagcaaaaagaaaaagacacaacctaagctttcagctctttcagct
ggatcgaatgagtacctcaggagtatctccttgccagtgccagtcctggtggaggacacg
agcagcagcagcgagtacggctcagtttcccctgacacagagttgaaggtggaccccttc
tctttcaaaacaagagccaagtcctgtggagaaaaggatgtcaaaggcatccggacgctg
tttctgggcatccctgatgaaaattttgaagaccacagtgctccaccttctccagaagaa
aaagattccggattctttatgctgaggaaggacagtgagagacgggccacgcttcacagg
attctgacggaagaccaagacaaagttgtgagaaacttaatggaatccttggctcagggg
gctgaagaacctaaactgaaatgggaacacatcacaactctggtcgcaagcctcagagaa
tttgtgaggtccacggaccggaagatcatagccaccaccctgtccaagctgaagctggag
ctggacttcgacagccacgggatcagtcaggtccaggtggtgctctttggtttccaagat
gctgtcaataaagttcttcggaatcataacatcaagccacactggatgtttgccttagac
agtatcatccgaaaggcggtacagacagctattaccattctggttccagaactgaggccg
catttcagccttgcatctgagagtgatactgccgatcaagaagacttggatgcagaaggt
gaccatgacgaacggccttcaaatcaaactgtccgaagacctcatgccgtccttgaagac
gcggtggccacctcaggggtgagcacgctcagttctactgtatcccatgactcccagagt
gctcaccgatcactgaatgtacagcttggaaggatgaaaatagaaacaaatagattactg
gaagaattggttcagaaagagaaagaattacaagcactccttcatcaagctattgaagag
aaagaccaagaaattaaacacctgaagcttaagtcccaaccaatagatgttcctgggttg
cctgggtgtcactccagttctcctggcacaaacactgaagattcggaacttactgactgg
ctgagagagaacggagccgatgaagacactataagtcggtttttggctgaggattattca
ttaatggatgttctctactatgttacacgtgatgatttaaaatgcctgagactaaggggc
gggatgctgtgcacactgtggaaagccatcactgacttccgagacaaacaggcttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (20)   
   KEGG PATHWAY (20)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (41)   

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