KEGG   Bos taurus (cow): 338049
Entry
338049            CDS       T01008                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA
  KO
K04513  Ras homolog gene family, member A
Organism
bta  Bos taurus (cow)
Pathway
bta04014  Ras signaling pathway
bta04015  Rap1 signaling pathway
bta04022  cGMP-PKG signaling pathway
bta04024  cAMP signaling pathway
bta04062  Chemokine signaling pathway
bta04071  Sphingolipid signaling pathway
bta04072  Phospholipase D signaling pathway
bta04144  Endocytosis
bta04150  mTOR signaling pathway
bta04270  Vascular smooth muscle contraction
bta04310  Wnt signaling pathway
bta04350  TGF-beta signaling pathway
bta04360  Axon guidance
bta04510  Focal adhesion
bta04520  Adherens junction
bta04530  Tight junction
bta04611  Platelet activation
bta04621  NOD-like receptor signaling pathway
bta04625  C-type lectin receptor signaling pathway
bta04660  T cell receptor signaling pathway
bta04670  Leukocyte transendothelial migration
bta04722  Neurotrophin signaling pathway
bta04810  Regulation of actin cytoskeleton
bta04921  Oxytocin signaling pathway
bta04928  Parathyroid hormone synthesis, secretion and action
bta04972  Pancreatic secretion
bta05100  Bacterial invasion of epithelial cells
bta05132  Salmonella infection
bta05133  Pertussis
bta05135  Yersinia infection
bta05152  Tuberculosis
bta05163  Human cytomegalovirus infection
bta05200  Pathways in cancer
bta05203  Viral carcinogenesis
bta05205  Proteoglycans in cancer
bta05206  MicroRNAs in cancer
bta05210  Colorectal cancer
bta05417  Lipid and atherosclerosis
bta05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    338049 (RHOA)
   04015 Rap1 signaling pathway
    338049 (RHOA)
   04310 Wnt signaling pathway
    338049 (RHOA)
   04350 TGF-beta signaling pathway
    338049 (RHOA)
   04072 Phospholipase D signaling pathway
    338049 (RHOA)
   04071 Sphingolipid signaling pathway
    338049 (RHOA)
   04024 cAMP signaling pathway
    338049 (RHOA)
   04022 cGMP-PKG signaling pathway
    338049 (RHOA)
   04150 mTOR signaling pathway
    338049 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    338049 (RHOA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    338049 (RHOA)
   04520 Adherens junction
    338049 (RHOA)
   04530 Tight junction
    338049 (RHOA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    338049 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    338049 (RHOA)
   04621 NOD-like receptor signaling pathway
    338049 (RHOA)
   04625 C-type lectin receptor signaling pathway
    338049 (RHOA)
   04660 T cell receptor signaling pathway
    338049 (RHOA)
   04670 Leukocyte transendothelial migration
    338049 (RHOA)
   04062 Chemokine signaling pathway
    338049 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    338049 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    338049 (RHOA)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    338049 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    338049 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    338049 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    338049 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    338049 (RHOA)
   05206 MicroRNAs in cancer
    338049 (RHOA)
   05205 Proteoglycans in cancer
    338049 (RHOA)
   05203 Viral carcinogenesis
    338049 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    338049 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    338049 (RHOA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    338049 (RHOA)
   05135 Yersinia infection
    338049 (RHOA)
   05133 Pertussis
    338049 (RHOA)
   05152 Tuberculosis
    338049 (RHOA)
   05100 Bacterial invasion of epithelial cells
    338049 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    338049 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    338049 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:bta04131]
    338049 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bta04147]
    338049 (RHOA)
   04031 GTP-binding proteins [BR:bta04031]
    338049 (RHOA)
Membrane trafficking [BR:bta04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    338049 (RHOA)
Exosome [BR:bta04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   338049 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   338049 (RHOA)
  Exosomal proteins of colorectal cancer cells
   338049 (RHOA)
  Exosomal proteins of bladder cancer cells
   338049 (RHOA)
GTP-binding proteins [BR:bta04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    338049 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 338049
NCBI-ProteinID: NP_788818
BGD-bta: BT11858
Ensembl: ENSBTAG00000004279
VGNC: 33943
UniProt: P61585
Position
22:50701226..50751133
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatccggaagaaactggtgattgttggagatggagcctgtggcaagacttgc
ttgcttattgtctttagcaaggaccagttcccagaggtgtatgtccctacggtgtttgag
aactatgtggcagatattgaagtggatggaaagcaggtagagttggctttatgggacaca
gctgggcaggaagattatgatcgcttgaggcctctctcctacccggataccgacgttata
ctgatgtgtttctccattgatagccctgatagtttagaaaacataccagaaaaatggact
ccggaagtcaagcatttctgtcccaacgtgcccatcatcctggttgggaacaagaaggat
cttcgaaacgacgagcacacaaggcgggagctggccaagatgaagcaggagccagtaaaa
cccgaagaaggcagagatatggcaaacaggattggtgcttttgggtacatggagtgttca
gcaaagaccaaagatggagtgagggaggtttttgaaatggccacgagagctgctctgcaa
gccagacgtgggaagaaaaaatctgggtgccttgtcttgtga

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