KEGG   Bos taurus (cow): 537960
Entry
537960            CDS       T01008                                 
Symbol
ATP1A4
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-4
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
bta  Bos taurus (cow)
Pathway
bta04022  cGMP-PKG signaling pathway
bta04024  cAMP signaling pathway
bta04260  Cardiac muscle contraction
bta04261  Adrenergic signaling in cardiomyocytes
bta04820  Cytoskeleton in muscle cells
bta04911  Insulin secretion
bta04918  Thyroid hormone synthesis
bta04919  Thyroid hormone signaling pathway
bta04925  Aldosterone synthesis and secretion
bta04960  Aldosterone-regulated sodium reabsorption
bta04961  Endocrine and other factor-regulated calcium reabsorption
bta04964  Proximal tubule bicarbonate reclamation
bta04970  Salivary secretion
bta04971  Gastric acid secretion
bta04972  Pancreatic secretion
bta04973  Carbohydrate digestion and absorption
bta04974  Protein digestion and absorption
bta04976  Bile secretion
bta04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:bta00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    537960 (ATP1A4)
   04022 cGMP-PKG signaling pathway
    537960 (ATP1A4)
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    537960 (ATP1A4)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    537960 (ATP1A4)
   04918 Thyroid hormone synthesis
    537960 (ATP1A4)
   04919 Thyroid hormone signaling pathway
    537960 (ATP1A4)
   04925 Aldosterone synthesis and secretion
    537960 (ATP1A4)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    537960 (ATP1A4)
   04261 Adrenergic signaling in cardiomyocytes
    537960 (ATP1A4)
  09154 Digestive system
   04970 Salivary secretion
    537960 (ATP1A4)
   04971 Gastric acid secretion
    537960 (ATP1A4)
   04972 Pancreatic secretion
    537960 (ATP1A4)
   04976 Bile secretion
    537960 (ATP1A4)
   04973 Carbohydrate digestion and absorption
    537960 (ATP1A4)
   04974 Protein digestion and absorption
    537960 (ATP1A4)
   04978 Mineral absorption
    537960 (ATP1A4)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    537960 (ATP1A4)
   04961 Endocrine and other factor-regulated calcium reabsorption
    537960 (ATP1A4)
   04964 Proximal tubule bicarbonate reclamation
    537960 (ATP1A4)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:bta04147]
    537960 (ATP1A4)
Enzymes [BR:bta01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     537960 (ATP1A4)
Exosome [BR:bta04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   537960 (ATP1A4)
  Exosomal proteins of other body fluids (saliva and urine)
   537960 (ATP1A4)
  Exosomal proteins of colorectal cancer cells
   537960 (ATP1A4)
  Exosomal proteins of bladder cancer cells
   537960 (ATP1A4)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Hydrolase Cation_ATPase_N Hydrolase_3 HAD
Other DBs
NCBI-GeneID: 537960
NCBI-ProteinID: NP_001137575
BGD-bta: BT27450
Ensembl: ENSBTAG00000038523
VGNC: 26284
UniProt: E1B8N5
Position
3:complement(9487986..9520838)
AA seq 1030 aa
MGLGGKKGAVTPHERNPNPGPTNSPKMSKKKMKRKKKKKDIEELKKEVVMDDHKLTLDEL
SAKYSVDLTRGHSPEKAQEILTRDGPNALTPPSTTPEWVKFCKQLFGGFSLLLWTGAILC
FVAFGIQLYFNEDTTKDNLYLGIVLTVVVIITGCFSYYQEAKSSKIMESFKNMVPQQALV
IRGGEKFQIPVYEVVVGDLVEVKGGDRIPADIRLISSQGCKVDNSSLTGESEPQSRSTEF
TNENPLETQNICFFSTNCVEGSAQGIVIATGDSTVMGRIASLTSGLAVGKTPIAIELEHF
IHLITGVAVFLGVTFFGLSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRM
ARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHLWFDKTIYEADTTEEQTGNPF
AKGSDTWFILARIAGLCNRADFKANEESLPIAKRATTGDASESALLKFIEQSYSSVNEMR
EKSPKVAEIPFNSTNKYQVSIHLREDSSQAHVLMMKGAPERILEFCSTYLLKGQEYPIDD
EMKDAFQNAYLDLGGLGERVLGFCFLNLPNTYPKGFKFNTDEINFPINNLCFVGLISMID
PPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGSETAEDIAARLKIPVS
KVNPRDAQAIVVHGSELKNMNSEQLDEILQNHTEIVFARTSPQQKLIIVEGCQRLGAIVA
VTGDGVNDSPALKKADIGIAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLK
KSIAYTLTSNIPEITPFLMFIILGIPLPLGTITILCIDLGTDMVPAISLAYESAESDIMK
RAPRNSKTDKLVNHRLIGMAYGQIGMIQALAGFFTYFVILAENGFKPPDLLGIRVNWENR
YINDLEDSYGQQWTYEQRKVLEFTCQTAFFVSIVIVQWADLIICKTRRNSIFQQGMKNKI
LIFGILEETILAAFLSYTPGMDVALRMYPLKITWWFCATPYSLLIFVYDEIRRLIIRRYP
GGWVEKETYY
NT seq 3093 nt   +upstreamnt  +downstreamnt
atggggcttggagggaaaaaaggggccgtgacacctcatgagcggaatccaaacccagga
cctacaaacagtcctaagatgagtaaaaaaaaaatgaagaggaaaaaaaagaagaaagat
atagaggagctgaagaaggaagtagtcatggatgatcacaaattaaccttggatgagctg
agcgccaagtactctgtggacctgaccaggggccatagccctgaaaaggcgcaggaaatc
ctgactcgagatggacccaatgcactgacccctccctctaccactccagaatgggtcaaa
ttctgcaagcagcttttcggcggcttctccctcctgctgtggactggtgccattctttgc
ttcgtggccttcggcatccagttgtatttcaatgaggacaccaccaaagacaacctgtac
ctgggcattgtactaactgtcgtggtcatcatcactggctgcttctcctattatcaggaa
gccaagagctccaagatcatggaatcttttaagaacatggtacctcagcaagctctggtc
attcgaggtggagagaagtttcagatccctgtatacgaagtggtggtaggcgacctggta
gaagtgaagggtggggatcggattcccgctgacatccggcttatctcttcacaaggatgt
aaggtggacaactcatccttgacaggagagtcagagccccagtcccgctccactgagttc
accaatgagaaccctctggagacccaaaatatctgcttcttctccaccaactgtgtggaa
ggctcagcccaaggtattgtgattgccaccggagactccaccgtgatgggccgtatagcc
tcactgacctccggtctggcagtgggcaagacccccattgctattgagcttgaacacttc
atccatctgatcacaggggtggccgtcttcctgggtgtcactttctttgggctctcgctt
atcttgggctacacctggctggaggctgtcattttccttatcggcatcattgtggccaac
gtgcctgagggactgctggccaccgtcacagtatgcctgaccctgacagccaagcgcatg
gctcggaagaactgcctggtgaagaacctggaggcggtggagactctgggctccacctcc
accatctgctctgacaagacgggcaccctcacccagaaccgcatgaccgtcgcccacctg
tggttcgacaagaccatctacgaggcggacaccactgaagaacagactgggaatccattt
gccaagggctctgacacctggtttatcctggcccgaatcgctggcctctgcaaccgggct
gattttaaggcgaatgaggagagccttcccatagctaagcgggcaacaacaggagatgct
tcggagtcagcgctcctcaagttcatcgagcagtcctacagctctgtgaacgagatgaga
gagaaaagccccaaggtggcagagattccctttaattctaccaacaagtaccaggtgtcc
atccacctgagggaagacagctcccaggcccacgtcctgatgatgaagggggcgcccgag
aggatcttagaattttgctctacttaccttctgaaagggcaggagtacccaatagacgat
gaaatgaaggacgccttccaaaacgcctacttggatctgggaggtctgggggagcgtgtg
ctagggttctgcttcttgaatctgcctaacacttaccccaagggattcaagtttaacacc
gatgaaatcaactttcccataaataacctctgtttcgtggggctcatctccatgattgac
cctccccgagctgccgtgcccgatgctgtgggcaagtgccggagtgctgggattaaggtg
attatggtaacaggggatcatcccatcacagccaaggccattgccaagggtgtgggcatc
atctcagagggctctgagacagcagaggacattgctgcccggctcaagatccctgtcagc
aaggtcaatcctagggacgcccaagccattgtggtgcatggctcagaactaaagaatatg
aactctgagcagcttgatgagatcctccaaaaccacactgagatcgtgttcgctcggacc
tcaccccagcagaagctcatcattgtagagggatgtcagaggctgggagccattgtggca
gtgacaggggatggggtgaacgactccccggcactgaagaaggcggacatcggcatcgcc
atgggcatcgccggctccgacgtgtctaagcaggccgctgacatgatcctactggatgac
aactttgcttccattgtcacgggtgtggaggagggccgcctgatctttgacaacctgaag
aaatccatcgcctacaccctgaccagcaacatccccgagatcacccccttcctgatgttc
atcatcctcggcatccccctgcctctgggcaccataaccatcctctgcattgacctgggc
actgacatggtccctgctatctccctggcttatgagtcagctgagagtgacatcatgaag
agggctccacggaactcaaagactgataagctagtgaatcaccgtctcattggcatggcc
tacggacagatagggatgatccaggctctggcaggattcttcacctactttgtgatcttg
gctgagaatggttttaagcctcctgatctgctgggcatccgcgtcaactgggaaaatcga
tacatcaatgacctggaggacagctatggacagcagtggacctatgagcagcggaaggtg
ctggagttcacgtgccaaacggccttcttcgtcagcatcgtgatcgtgcagtgggctgac
ctcatcatctgtaagacccgtcgcaactcaatcttccagcagggcatgaaaaacaagatc
ctcatatttgggatcctggaggagacaatcctggccgcttttctgtcctacacgccaggc
atggatgtagctctgcgaatgtacccactcaagataacctggtggttctgtgccaccccc
tacagcctcctcatctttgtgtatgatgaaataagaagactcatcattcgtcgttatccc
ggtggctgggtggagaaggagacctactactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (19)   
   KEGG PATHWAY (19)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (42)   
   KEGG ORTHOLOGY (1)   
   RefGene (35)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (7)   
   UniProt (1)   
   RefSeq(pep) (6)   
DNA sequence (8)   
   RefSeq(nuc) (6)   
   GenBank (1)   
   EMBL (1)   
Protein domain (7)   
   Pfam (7)   
All databases (88)   

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