KEGG   Colobus angolensis palliatus (Angola colobus): 105510999
Entry
105510999         CDS       T08744                                 
Symbol
PLCB1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
cang  Colobus angolensis palliatus (Angola colobus)
Pathway
cang00562  Inositol phosphate metabolism
cang01100  Metabolic pathways
cang04015  Rap1 signaling pathway
cang04020  Calcium signaling pathway
cang04022  cGMP-PKG signaling pathway
cang04062  Chemokine signaling pathway
cang04070  Phosphatidylinositol signaling system
cang04071  Sphingolipid signaling pathway
cang04072  Phospholipase D signaling pathway
cang04261  Adrenergic signaling in cardiomyocytes
cang04270  Vascular smooth muscle contraction
cang04310  Wnt signaling pathway
cang04371  Apelin signaling pathway
cang04540  Gap junction
cang04611  Platelet activation
cang04613  Neutrophil extracellular trap formation
cang04621  NOD-like receptor signaling pathway
cang04713  Circadian entrainment
cang04720  Long-term potentiation
cang04723  Retrograde endocannabinoid signaling
cang04724  Glutamatergic synapse
cang04725  Cholinergic synapse
cang04726  Serotonergic synapse
cang04728  Dopaminergic synapse
cang04730  Long-term depression
cang04742  Taste transduction
cang04750  Inflammatory mediator regulation of TRP channels
cang04911  Insulin secretion
cang04912  GnRH signaling pathway
cang04915  Estrogen signaling pathway
cang04916  Melanogenesis
cang04918  Thyroid hormone synthesis
cang04919  Thyroid hormone signaling pathway
cang04921  Oxytocin signaling pathway
cang04922  Glucagon signaling pathway
cang04924  Renin secretion
cang04925  Aldosterone synthesis and secretion
cang04926  Relaxin signaling pathway
cang04927  Cortisol synthesis and secretion
cang04928  Parathyroid hormone synthesis, secretion and action
cang04929  GnRH secretion
cang04933  AGE-RAGE signaling pathway in diabetic complications
cang04934  Cushing syndrome
cang04935  Growth hormone synthesis, secretion and action
cang04961  Endocrine and other factor-regulated calcium reabsorption
cang04970  Salivary secretion
cang04971  Gastric acid secretion
cang04972  Pancreatic secretion
cang04973  Carbohydrate digestion and absorption
cang05010  Alzheimer disease
cang05016  Huntington disease
cang05017  Spinocerebellar ataxia
cang05022  Pathways of neurodegeneration - multiple diseases
cang05142  Chagas disease
cang05143  African trypanosomiasis
cang05146  Amoebiasis
cang05163  Human cytomegalovirus infection
cang05200  Pathways in cancer
cang05415  Diabetic cardiomyopathy
cang05417  Lipid and atherosclerosis
Module
cang_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cang00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    105510999 (PLCB1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    105510999 (PLCB1)
   04310 Wnt signaling pathway
    105510999 (PLCB1)
   04371 Apelin signaling pathway
    105510999 (PLCB1)
   04020 Calcium signaling pathway
    105510999 (PLCB1)
   04070 Phosphatidylinositol signaling system
    105510999 (PLCB1)
   04072 Phospholipase D signaling pathway
    105510999 (PLCB1)
   04071 Sphingolipid signaling pathway
    105510999 (PLCB1)
   04022 cGMP-PKG signaling pathway
    105510999 (PLCB1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    105510999 (PLCB1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    105510999 (PLCB1)
   04613 Neutrophil extracellular trap formation
    105510999 (PLCB1)
   04621 NOD-like receptor signaling pathway
    105510999 (PLCB1)
   04062 Chemokine signaling pathway
    105510999 (PLCB1)
  09152 Endocrine system
   04911 Insulin secretion
    105510999 (PLCB1)
   04922 Glucagon signaling pathway
    105510999 (PLCB1)
   04929 GnRH secretion
    105510999 (PLCB1)
   04912 GnRH signaling pathway
    105510999 (PLCB1)
   04915 Estrogen signaling pathway
    105510999 (PLCB1)
   04921 Oxytocin signaling pathway
    105510999 (PLCB1)
   04926 Relaxin signaling pathway
    105510999 (PLCB1)
   04935 Growth hormone synthesis, secretion and action
    105510999 (PLCB1)
   04918 Thyroid hormone synthesis
    105510999 (PLCB1)
   04919 Thyroid hormone signaling pathway
    105510999 (PLCB1)
   04928 Parathyroid hormone synthesis, secretion and action
    105510999 (PLCB1)
   04916 Melanogenesis
    105510999 (PLCB1)
   04924 Renin secretion
    105510999 (PLCB1)
   04925 Aldosterone synthesis and secretion
    105510999 (PLCB1)
   04927 Cortisol synthesis and secretion
    105510999 (PLCB1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    105510999 (PLCB1)
   04270 Vascular smooth muscle contraction
    105510999 (PLCB1)
  09154 Digestive system
   04970 Salivary secretion
    105510999 (PLCB1)
   04971 Gastric acid secretion
    105510999 (PLCB1)
   04972 Pancreatic secretion
    105510999 (PLCB1)
   04973 Carbohydrate digestion and absorption
    105510999 (PLCB1)
  09155 Excretory system
   04961 Endocrine and other factor-regulated calcium reabsorption
    105510999 (PLCB1)
  09156 Nervous system
   04724 Glutamatergic synapse
    105510999 (PLCB1)
   04725 Cholinergic synapse
    105510999 (PLCB1)
   04728 Dopaminergic synapse
    105510999 (PLCB1)
   04726 Serotonergic synapse
    105510999 (PLCB1)
   04720 Long-term potentiation
    105510999 (PLCB1)
   04730 Long-term depression
    105510999 (PLCB1)
   04723 Retrograde endocannabinoid signaling
    105510999 (PLCB1)
  09157 Sensory system
   04742 Taste transduction
    105510999 (PLCB1)
   04750 Inflammatory mediator regulation of TRP channels
    105510999 (PLCB1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    105510999 (PLCB1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105510999 (PLCB1)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    105510999 (PLCB1)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    105510999 (PLCB1)
   05142 Chagas disease
    105510999 (PLCB1)
   05143 African trypanosomiasis
    105510999 (PLCB1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    105510999 (PLCB1)
   05016 Huntington disease
    105510999 (PLCB1)
   05017 Spinocerebellar ataxia
    105510999 (PLCB1)
   05022 Pathways of neurodegeneration - multiple diseases
    105510999 (PLCB1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    105510999 (PLCB1)
   05415 Diabetic cardiomyopathy
    105510999 (PLCB1)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    105510999 (PLCB1)
   04934 Cushing syndrome
    105510999 (PLCB1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cang04131]
    105510999 (PLCB1)
Enzymes [BR:cang01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     105510999 (PLCB1)
Membrane trafficking [BR:cang04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    105510999 (PLCB1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    105510999 (PLCB1)
SSDB
Motif
Pfam: PI-PLC-X PH_14 PI-PLC-Y PLC-beta_C EF-hand_like DUF1154
Other DBs
NCBI-GeneID: 105510999
NCBI-ProteinID: XP_011796392
Ensembl: ENSCANG00000041852
UniProt: A0A2K5K5U0
Position
Unknown
AA seq 1173 aa
MAGAQPGVHALQLKPVCVSDSLKKGTKFVKWDDDSTIVTPIILRTDPQGFFFYWTDQNKE
TELLDLSLVKDARCGRHAKAPKDPKLRELLDVGNIGRLEQRMITVVYGPDLVNISHLNLV
AFQEEVAKEWTNEVFSLATNLLAQNMSRDAFLEKAYTKLKLQVTPEGRIPLKNIYRLFSA
DRKRVETALEACSLPSSRNDSIPQEDFTPEVYRVFLNNLCPRPEIDNIFSEFGAKSKPYL
TVDQMMDFINLKQRDPRLNEILYPPLKQEQVQVLIEKYEPNNSLAKKGQISVDGFMRYLS
GEENGVVSPEKLDLNEDMSQPLSHYFINSSHNTYLTAGQLAGNSSVEMYRQVLLSGCRCV
ELDCWKGRTAEEEPVITHGFTMTTEISFKEVIEAIAECAFKTSPFPILLSFENHVDSPKQ
QAKMAEYCRLIFGDALLMEPLEKYPLESGVPLPSPMDLMYKILVKNKKKSHKSSEGSGKK
KLSEQASNTCSDSSSMFEPSSPGAGEADTESDDDDDDDDCKKSSMDEGTAGSEAMATEEM
SNLVNYIQPVKFESFEISKKRNKSFEMSSFVETKGLEQLTKSPVEFVEYNKMQLSRIYPK
GTRVDSSNYMPQLFWNAGCQMVALNFQTMDLAMQINMGMYEYNGKSGYRLKPEFMRRPDK
HFDPFTEGIVDGIVANTLSVKIISGQFLSDKKVGTYVEVDMFGLPVDTRRKAFKTKTSQG
NAVNPVWEEEPIVFKKVVLPTLACLRVAVYEEGGKFIGHRILPVQAIRPGYHYICLRNER
NQPLTLPAVFVYIEVKDYVPDTYADVIEALSNPIRYVNLMEQRAKQLAALTLEDEEDVKK
EADPGETPSETPSEVRTTPAENGVNHTTSLTPKPPSQALHSQPAPGSVKAPAKTEDLIQS
VLTEVEAQTIEELKQQKSFVKLQKKHYKEMKDLVKRHHKKTTDLIKEHTTKYNEIQNDYL
RRRAALEKSAKKDSKKKSEPSSPDHGSSTIEQDLAALDAEMTQKLIDLKDKQQQQLLNLR
QEQYYSEKYQKREHIKLLIQKLTDVAEECQNNQLKKLKEICEKEKKELKKKMDKKRQEKI
TEAKSKDKSQMEEEKTEMIRSYIQEVVQYIKRLEEAQSKRQEKLVEKHKEIRQQILDEKP
KGEGSSSFLSETCHEDPSVSPNFTPPNPQALKW
NT seq 3522 nt   +upstreamnt  +downstreamnt
atggccggggctcaacccggagtgcacgccttgcaactcaagcccgtgtgcgtgtccgac
agcctcaagaagggcaccaaattcgtcaagtgggatgatgactcaactattgttactcca
attattttgaggactgaccctcagggatttttcttttactggacagatcaaaacaaggag
acggagctactggatctcagccttgtcaaagatgccagatgtgggagacacgccaaagct
cccaaggaccccaaattacgtgaacttttggatgtggggaacattgggcgcctggagcag
cgcatgatcacagtggtgtatggacctgacctcgtgaacatctcccatttgaatctcgtg
gctttccaagaagaagtggccaaggaatggacaaacgaggttttcagtttggcaacaaac
ctgctggcccaaaacatgtccagggatgcatttctggaaaaagcctatactaaacttaag
ctgcaagtcactccagaagggcgtattcctctcaaaaacatatatcgcttgttttcagca
gaccggaagagagttgaaactgctttagaggcttgtagtcttccatcttcaaggaatgat
tcaatacctcaagaagatttcacgccagaagtgtacagagttttcctcaacaacctttgc
cctcgacctgaaattgataacatcttttcagaatttggtgccaaaagcaaaccatatctt
accgttgaccagatgatggattttatcaaccttaagcagcgagatcctcggcttaatgaa
atactttatccacctctaaaacaagagcaagtccaagtattgattgagaagtatgaaccc
aacaacagcctcgccaaaaaaggacaaatatcagtggatgggttcatgcgctatctgagt
ggagaagaaaacggagtcgtttcacctgagaaactggatttgaatgaagacatgtctcag
cccctttctcactatttcattaattcctcgcacaacacctacctcacagctggccaactg
gctggaaactcctctgttgagatgtatcgccaagtgcttctgtctggttgtcgctgtgtg
gagctggactgctggaagggacgaactgcagaagaggaacctgtcatcacccatggcttc
accatgacaactgaaatatctttcaaggaagtgatagaagcaatagcggagtgtgcattt
aagacttcaccatttccaattctcctttcatttgagaaccatgtggattccccaaagcag
caagccaagatggcggagtactgccgactgatctttggggatgcccttctcatggagccc
ctggaaaaatatccactggaatctggagttcctcttccaagccctatggatttaatgtat
aaaattttggtgaaaaataagaagaaatcacacaagtcatcagaaggaagtggcaaaaag
aagctctcagaacaagcctccaacacctgcagcgactcctccagcatgttcgagccttca
tccccaggagccggagaagctgatacggaaagtgacgacgatgatgatgatgatgactgt
aaaaaatcttcaatggatgaggggaccgctggaagtgaggctatggccacagaagaaatg
tctaacctggtgaactacattcagccggtcaagtttgagtcatttgaaatttcaaaaaaa
agaaataaaagttttgaaatgtcttccttcgtggaaaccaaaggacttgaacaactcacc
aagtctccggtggaatttgtagaatataacaaaatgcagcttagcaggatatatccaaaa
ggaacacgtgtggattcatccaactatatgcctcagctcttctggaatgcaggttgtcag
atggtggcacttaatttccagacaatggacctggctatgcaaataaatatggggatgtat
gaatacaacggaaagagtggctatagattgaagccagagttcatgaggaggcctgacaag
cattttgatccatttactgaaggcatcgtagatgggatagtggcaaacactttgtctgtt
aagattatttcaggtcagtttctttctgataagaaagtcgggacttacgtggaagtggat
atgtttggcttgcctgtggatacaaggaggaaggcatttaagaccaagacatcccaagga
aatgctgtgaatcctgtctgggaagaagaacctattgtgttcaaaaaggtggttcttcct
actctggcctgtttgagagtagcagtttatgaagaaggaggtaaattcattggccaccgt
atcttgccagtgcaagccattcggccaggctatcactatatatgtctaaggaatgaaagg
aaccagcctctgacgctgcctgctgtctttgtctacatagaagtgaaagactatgtgcca
gacacatatgcagatgtcattgaagctttatcaaacccaatccggtatgtgaacctgatg
gagcagagagctaagcaattggctgctttgacactggaagatgaagaagacgtaaagaaa
gaggctgatcctggagaaacaccatcagagactccaagtgaagtgagaacaactccagcc
gaaaacggggtgaatcacactacatccctgacacccaagccaccctcccaggctctccac
agccagccagctccaggttctgtaaaggcacctgccaaaacagaagatcttattcagagt
gtcttaacagaagtggaagcacagaccatcgaagagctaaagcaacagaaatcgtttgtg
aaacttcaaaagaagcactacaaagaaatgaaagacctggttaagagacaccacaagaaa
accactgaccttatcaaagaacacactaccaagtataatgaaattcagaatgactacttg
agaaggagagcagctttggaaaagtccgccaaaaaggacagtaagaaaaaatcggaaccc
agcagccctgatcatggttcatcaacgattgagcaagacctcgctgccctggatgctgaa
atgacccaaaaattaatagacttgaaggacaaacaacagcagcagctgcttaatcttcga
caagaacagtattatagtgaaaaataccagaagcgagaacatattaaactgcttattcaa
aagttgacggatgtcgcagaagagtgtcagaacaatcagttaaagaagctcaaagaaatc
tgtgagaaagaaaagaaagaattaaagaagaaaatggataaaaagaggcaggagaagata
acagaagctaaatctaaagacaaaagtcagatggaagaggagaagacagagatgatccgg
tcatatatccaggaagtggtgcagtacatcaagaggctagaagaggcgcaaagtaaacgg
caagaaaaactcgtagagaaacacaaggaaatacgtcagcagatcctggatgaaaagccc
aagggggaaggttcctcctcattcttgtcggaaacttgccatgaggatccctctgtttcc
cccaactttactccccccaaccctcaagctctcaagtggtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (61)   
   KEGG PATHWAY (60)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (90)   

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