KEGG   Castor canadensis (American beaver): 109686786
Entry
109686786         CDS       T04791                                 
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
  KO
K01930  folylpolyglutamate synthase [EC:6.3.2.17]
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan00790  Folate biosynthesis
ccan01100  Metabolic pathways
ccan01240  Biosynthesis of cofactors
ccan01523  Antifolate resistance
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    109686786 (Fpgs)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    109686786 (Fpgs)
Enzymes [BR:ccan01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.17  tetrahydrofolate synthase
     109686786 (Fpgs)
SSDB
Motif
Pfam: Mur_ligase_M Mur_ligase_C
Other DBs
NCBI-GeneID: 109686786
NCBI-ProteinID: XP_020019864
UniProt: A0A8B7ULS5
Position
Unknown
AA seq 587 aa
MWWAQRHLRAALSLAAVSARSATTEVAARRGLSAWPAPQEPGMEYQDAVRMLNTLQTNAS
YLEQVKRQRSDPQSQLEAMERYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTEHILRN
YGLKTGFFSSPHLVQVRERIRINGQPISPELFTKHFWRLYHRLEETKDSSCVSMPAYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTMEKIA
WQKGGIFKHGIPAFTVLQPEGPLAVLRDRAQQISCPLYLCPPLEALEEGAPPLILGLEGE
HQRSNAALALQLAHCWLQHHNNQDIQELKMSRPSVRWQLPLAPVFQPTSHMRHGLRDTEW
PGRTQVLLRGPLTWYLDGAHTTSSIQACVRWYRQALQRRERPSGGPEVRVLLFNSTGDRD
PAALLKLLQPCRFDYAVFCPNLTEVSSTGSADQQNFTVTLDQVLLRCLQHQQHWNCLGEE
QDSSDLWSSPNLEPSGPTSLLLAPHSPHPCSASSLVFSCISHALQWISQGRDPIFQPPSP
PRGLLAHPVANSGATVLREAAAIQVLVTGSLHLVGGVLKLLEPSMSQ
NT seq 1764 nt   +upstreamnt  +downstreamnt
atgtggtgggcgcagcgccatctgcgcgcagctctgtctctagcagccgtttctgctcgt
agtgcaacaaccgaggtcgcggcgcggcgggggttgagcgcgtggccggcgccgcaggag
cccggcatggagtatcaggatgccgtgcggatgctcaacaccctgcagaccaacgccagc
tacctggagcaggtgaagcgccaacggagtgacccccagtcacagttggaagccatggaa
cggtaccttgcacggagtgggctgcaggtggaggacctggaccggctgaacatcatccat
gtcactgggaccaaggggaagggctccacttgtgcctttactgagcatatcttgcggaat
tatggcctgaagacgggattctttagctctccccacctggtgcaggtgcgtgagcggatt
cgcatcaatgggcaacccatcagccccgagctcttcaccaagcacttctggcgcctctac
caccgactagaggagaccaaggacagcagctgtgtctccatgcctgcctacttccgcttc
cttacactcatggccttccatgtcttcctccaagaaaaggtcgacctggcagtggtagaa
gtgggcatcggcggggcttatgactgtacaaacatcatcaggaagcctgtggtgtgtgga
gtatcttctcttggcattgatcacaccagtcttctgggagacacaatggagaagatagcc
tggcagaaagggggcatctttaagcatggcatccctgccttcaccgtgctccagccagaa
ggtcccctggccgtgctgagggatcgagcccagcagatctcatgtcctctctacctgtgc
ccaccactggaagctctggaggaaggggcgccaccactgatcctgggcctggagggagag
caccagagatccaatgcagccttggccttgcagctggcccactgctggctccagcaccac
aacaaccaggacatccaggagctgaagatgtccaggccaagcgtccggtggcagctgccc
ctggcacctgtgttccagcccacatcccatatgcggcatgggcttcgagacacagagtgg
cctggccggacgcaggtgttactgcgtgggcccctcacttggtacttggatggcgcacat
accaccagcagcatccaggcctgtgtgcgctggtaccgccaggcgctgcagcgcagggag
aggccgagtggagggcccgaggtgcgtgtcttgctcttcaactccactggagacagagac
cctgccgccctgctgaagctactgcagccttgccggtttgactatgctgtcttctgtccc
aacctgacagaggtgtcatccacaggcagcgcagaccagcagaacttcactgtgacattg
gaccaggtgcttctccgttgcctccaacaccagcagcactggaactgcctgggtgaggag
caagatagctccgatctctggagttccccaaacctggagcctagtggacccacatccttg
ctgttggcaccccactcaccccatccctgcagtgccagctcccttgtcttcagctgcatc
tcccatgccttacagtggatcagccaaggccgggaccccatctttcagccacccagtccc
ccaaggggcctccttgcccaccccgtggccaacagtggggccactgttctccgtgaggct
gcagcaatccaagtgctggtcacgggcagcctgcatctggtgggcggtgtcctgaagctg
cttgagccctccatgtcccagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical substance (9)   
   KEGG COMPOUND (9)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (28)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (61)   

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