KEGG   Castor canadensis (American beaver): 109700897
Entry
109700897         CDS       T04791                                 
Symbol
Tiam1
Name
(RefSeq) T-lymphoma invasion and metastasis-inducing protein 1 isoform X1
  KO
K05731  T-lymphoma invasion and metastasis-inducing protein 1
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan04014  Ras signaling pathway
ccan04015  Rap1 signaling pathway
ccan04024  cAMP signaling pathway
ccan04062  Chemokine signaling pathway
ccan04530  Tight junction
ccan04810  Regulation of actin cytoskeleton
ccan05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    109700897 (Tiam1)
   04015 Rap1 signaling pathway
    109700897 (Tiam1)
   04024 cAMP signaling pathway
    109700897 (Tiam1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    109700897 (Tiam1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    109700897 (Tiam1)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    109700897 (Tiam1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    109700897 (Tiam1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:ccan04990]
    109700897 (Tiam1)
Domain-containing proteins not elsewhere classified [BR:ccan04990]
 Pleckstrin homology (PH) domain-containing proteins
  Dbl-Like RhoGEF family proteins
   109700897 (Tiam1)
SSDB
Motif
Pfam: Tiam_CC_Ex RhoGEF PH RBD PH_9 PDZ PH_11 PDZ_2 RNA_pol_Rpc82 PDZ_6
Other DBs
NCBI-GeneID: 109700897
NCBI-ProteinID: XP_020041835
UniProt: A0A8C0VZ70
Position
Unknown
AA seq 1591 aa
MGNAESQNVEHEFYGAKHASLGRKHTSRSLRLSHKTRRLRHASSGKVIHRDSEVSTRSSS
TPSIPQSLAENGLEPFSQEGTLEDFGSPIWVDRVDMGLRPVSYTDSSVTPSADSSIVLTA
ASVQSMPDSEECRLYGDDATYLAEGGRRQPLSTSNGPTFMETASFKKKRSKSADIWREDS
LEFSLSDLSQEHLTSNEEILGSAEEKDCEEARGMQTQASPRQLSTCQRANSLGDLYAQKN
SETAANGGPRNKFAGYCRNLVSDIPDLANHKMPPAAADENPSYSNYNTLPCRKSHCLSEG
ATNPQISLSNSMQGRRAKTTQDVNAGEGSEFADSGIEGATTDTDLLSRRSNATNSSYSPP
TSRAFVGSDSGSSSTGDAARQGVYENFRRELEMSTTNSESLEEAGSAHSDEHSSGTLSSP
GQSDILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKQYWVSLKGCTLFFYESD
GRCGIDHNSTPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWIT
AIHSACAAAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKKKKTI
LDQIFVWEQNLEQFQMDLFRFRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVS
SFHALVAARTGETGVRRRTQAMSRSTSKRRSRFSSLWGLDTTSKKKQGRPSINQVFGEGT
DAVKKSLEGIFDDIVPDGKREKEVVLPSVHQHNPDCDIWVHEYFTPSWFCLPNNQPALIV
VRPGDTARDTLELICKTHQLDYSAHYLRLKFLIENKMQFYVPQPEEDIYELLYKEIEICP
KVTQNILIEKSDTAADNYGFSLSSVEEDGVRRLYVNNVKEIGLASKTGLKAGAEILEINN
RAAGTLSSSVLKDFLSQPSLGLLVRTHPEPEGGVELLESPPHRVDGPVDLGESPLVFLTS
NPGHSLCSDQGSSAETAPEETEGPDLESSDETDHSSKSTEQVAAFCRSLHEMNPSDMSPS
PQDATGPQLATMRQLSDADKLRKVICELLETERTYVKDLNCLMERYLKPLQKETFLTQDE
LDVLFGNLTEMVEFQVEFLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFK
LYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPRQQHSFTLESYLIKPIQRVLKYPLLL
KELFALTDAESEEHYHLDVAIKTMNKVASHINEMQKIHEEFGAVFDQLIAEQTGEKKEVA
DLSMGDLLLHTNVIWLNPPASLGKWKKEPELAAFVFKTAVVLVYKDGSKQKKKLVGSHRL
SIYEEWDPFRFRHMIPTEALQVRALASADAEANAVCEIVHVKSESEGRPERVFHLCCSSP
ESRKDFLKAVHSILRDKHRRQLLKTESLPSSQQYVPFGGKRLCALKGARPAMSRAVSAPS
KSLGRRRRRLARNRFTIDSDAISASSPEKEPQQPPGGGDTDRWVEEQFDLAQYEEQDDIK
ETDILSDDEEFCESAKDASVPADLQERLQAASISPRDRGRRGLDSHASRMGQLKKQAALS
GINGRLESASEEVIWVRREDFAPSRKLNTEI
NT seq 4776 nt   +upstreamnt  +downstreamnt
atgggaaacgcagaaagccaaaatgtagagcatgagttttatggggcgaagcatgccagc
ctggggcgcaagcacacttcgcgctccctgcgcttgtcgcacaagacgcggcggctgcgc
cacgcctcctctgggaaggtgatccacagggactccgaagtgagcacgcggtccagcagc
acccccagcatcccccagtccctggccgaaaatggcctggagcccttctcccaggaaggc
accctagaggacttcgggagtcccatttgggtggaccgggtagatatgggtttgagaccc
gtgtcctatacggattcctccgtcactcccagcgcagacagcagcatcgtcctcactgca
gcctctgtgcagagcatgccagactcggaggagtgcaggctttacggggatgacgctacc
tatttggcagagggaggcaggaggcagcctctctctacatccaacgggcccaccttcatg
gagaccgcgagctttaagaagaaacgctccaaatctgcagacatctggcgggaggacagc
ctggaattctcactctccgatctgagccaagaacatttaaccagcaacgaagaaatcttg
ggttccgcggaagagaaggactgtgaggaagctcgggggatgcaaacacaggcgagtccg
cggcagctcagcacctgtcagcgggccaactccctgggtgacttgtatgctcagaaaaac
tctgagacggctgcaaacggaggaccaaggaacaaatttgcaggctactgtcggaatttg
gtgtctgatattcctgatcttgcaaaccataaaatgccaccagctgctgccgacgaaaat
ccttcatacagtaattataacacacttccctgtaggaaatctcactgtctttccgaaggt
gccaccaacccacaaattagccttagcaacagcatgcaaggcagaagagcaaaaacaact
caggatgttaatgcaggcgagggcagcgagtttgcagacagtgggattgaaggggccacc
accgacacggacctcctgtccaggcgatccaatgccaccaactccagctactcacccccc
accagccgggcctttgtgggcagcgacagtggcagcagctccaccggggatgcggctcgc
cagggggtgtacgagaacttcaggcgggagctggagatgagcaccaccaacagcgagagc
ctggaggaggcgggctccgcgcacagcgacgagcacagcagtggcaccctgagctcgccg
ggccagtcggacatcctgctgaccgccgcgcagggcaccgtgcgcaaggcgggcgcgctg
gcggtcaagaacttcctggtgcacaagaagaacaagaaggtggagtcggccacccgccgg
aagtggaagcagtactgggtgtccctgaaaggatgcacgctcttcttctacgaaagtgat
ggcaggtgtggaatagaccacaacagcacccccaagcacgctgtctgggtggagaacagt
attgtgcaggctgtgcctgagcaccccaagaaggactttgtcttctgcctcagcaattcc
ttgggtgacgccttcctctttcagaccaccagccagacagagctggaaaactggatcacc
gccatccattctgcctgtgcagctgctgttgcaagacaccaccacaaagaagacacactc
cggctcctcaagtcagaaatcaaaaagctggaacagaagatcgacatggatgaaaagatg
aagaaaatgggtgaaatgcagctgtcttcagtcactgactcaaagaagaagaaaactata
ttagatcagatctttgtttgggagcaaaatcttgaacagttccaaatggacctgttccgt
ttccgctgttacttagccagcctccaaggtggagagctgccaaaccccaaaaggctactt
gcttttgcaagccgaccaacaaaagtggcaatgggccgccttggaatcttctctgtgtca
tcttttcatgccctggtggcagcacgcactggcgaaactggagtgagaagacgtactcag
gccatgtccagatccacaagcaagcgaaggagcaggttttcttcactttggggtctggac
actacctccaaaaagaagcagggacgtccaagcatcaatcaggtgtttggagaaggaact
gacgctgtaaagaaatctctagagggcatatttgatgacattgttccagatggcaagagg
gagaaagaagtggtcttacctagtgtccaccagcataatcctgattgtgacatttgggtc
cacgagtatttcacgccatcctggttctgtctgcccaataatcagccagccctgatagtc
gtccgaccaggggacactgcacgggacaccctggagctgatttgcaagacacatcaactg
gattattctgctcattacctacgtctgaaatttctaatagaaaacaaaatgcagttctac
gttccacagcctgaagaggacatttatgagctgctgtataaagaaattgagatttgtccc
aaagtcactcagaacatcctcattgagaaatcagatacagctgctgataattacgggttt
tctctttcttctgtggaagaagatggtgttcgaaggctctatgtgaacaatgtgaaggaa
attggcttagcttccaagacaggcttgaaggcgggtgctgaaattcttgagatcaataat
cgagctgctggcaccctgagctcctctgtgctcaaagacttcctctcacagccctccctg
ggcctcctggtgaggacccacccagagccggagggaggagtggagctgctggagagccca
ccccaccgagtggacggccctgtggacctcggcgagagcccccttgtctttctcaccagc
aacccagggcacagtctctgcagcgaccagggcagtagtgctgagaccgctccagaagag
actgaggggccagacttggagtcctccgatgagacagatcacagcagcaagagcacagag
caggtggctgcattttgccgaagtttgcacgagatgaacccttcagatatgagcccatct
cctcaggacgccacagggcctcagctggccaccatgagacagctgtcggacgctgataag
ctgcgcaaggtcatctgtgagctgctggagacagagcgcacctatgtgaaagacttaaac
tgtctcatggagagatacctgaaacctcttcaaaaggagacttttctcacccaagatgag
cttgatgtgctctttggaaatttaaccgaaatggtagagtttcaagtagaattccttaaa
actctagaagatggagtgagactggttcctgacttggaaaagcttgagaaagtcgaccaa
tttaagaaagtgctcttctctctgggaggatcctttctgtactatgccgaccgcttcaag
ctctacagtgccttctgcgccagccacacaaaggtccccaaggtcctggtgaaggccaag
actgacacagccttcaaggcattcttggacgcccagaatccgcggcagcagcactcattc
actctggagtcttacctcatcaagcctatccagagggtcctcaagtatccacttctgctc
aaggagctgtttgccctgaccgatgcagagagcgaggagcactaccacctggatgtggcc
atcaagacaatgaacaaggttgccagtcatatcaacgagatgcagaaaattcacgaagaa
tttggggctgtctttgaccagctgattgctgagcagaccggtgagaagaaagaggtggca
gatctgagcatgggggatctgcttttgcacaccaatgtcatctggctaaacccgccggcc
tcactgggaaagtggaagaaagagccagagttggcagccttcgtcttcaaaactgctgtg
gtccttgtatataaagatggttccaaacagaagaagaaacttgtagggtcccacaggctt
tccatctacgaggagtgggaccccttccggtttcgacacatgatccctactgaggctctg
caggttcgagctttggcgagtgcagatgcagaggcaaatgccgtgtgtgaaattgtccat
gtgaaatcagagtcagaaggcaggccggagagggtcttccacctgtgctgcagctctcca
gaaagccggaaggatttcctgaaggctgtgcactccatcttgcgagataagcacagaaga
cagctccttaagactgaaagccttccctcatctcagcaatatgtcccttttggaggcaag
agattatgtgctctgaaaggcgccaggccagccatgagcagggcagtgtccgccccaagc
aagtcccttgggaggaggaggcggcgactggctcgcaacaggtttaccattgattccgat
gcgatctctgccagcagcccggagaaagagccccagcagccccccggtggcggggacact
gaccgatgggtagaggaacagtttgatcttgctcagtatgaggagcaagatgacatcaag
gagacagacatcctcagtgacgatgaggagttctgtgagtcggcgaaggacgcctcggtg
cctgcagacctgcaggagcggcttcaggctgcctccatcagtccacgcgacagaggccgg
aggggcctggacagccacgcgtcccgcatggggcagctcaagaagcaggccgccctgtcg
ggcatcaatgggcgtctggagagtgcaagtgaggaagtcatttgggttaggcgggaagac
tttgctccctccaggaaactgaacactgagatttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (7)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (10)   
   Pfam (10)   
All databases (44)   

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