KEGG   Corynebacterium diphtheriae VA01: CDVA01_0978
Entry
CDVA01_0978       CDS       T01702                                 
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
  KO
K00052  3-isopropylmalate dehydrogenase [EC:1.1.1.85]
Organism
cdv  Corynebacterium diphtheriae VA01
Pathway
cdv00290  Valine, leucine and isoleucine biosynthesis
cdv00660  C5-Branched dibasic acid metabolism
cdv01100  Metabolic pathways
cdv01110  Biosynthesis of secondary metabolites
cdv01210  2-Oxocarboxylic acid metabolism
cdv01230  Biosynthesis of amino acids
Module
cdv_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:cdv00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    CDVA01_0978 (leuB)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CDVA01_0978 (leuB)
Enzymes [BR:cdv01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.85  3-isopropylmalate dehydrogenase
     CDVA01_0978 (leuB)
SSDB
Motif
Pfam: Iso_dh
Other DBs
NCBI-ProteinID: AEX83247
Position
1032124..1033143
AA seq 339 aa
MKLAVIGGDGIGPEVTAEALKVLNAVRDDIEVTDYDLGARRYLRNGELLADADLVSLREH
DAILLGAIGAPGEVPPGVLERGLLLKMRFALDHHVNLRPSKLYPTATSPLANPGDIDFVV
VREGTEGLYCGNGGTLREGTPHEIASEVSQNTRYGVERVVRDAFERAQNRKKHLTLVHKT
NVLVNAGGLWQRTVNEIATEYPEVTVDYNHIDAATIYMVTDPSRYDVIVTDNLFGDILTD
LAGAVTGGIGLAASGNIDATGVNPSMFEPVHGSAPDIAGQGIADPTAAILSAAMLLRHVG
DESNAQRIEAAVTYDVAERPAGPVKTVEVGDRIVAALQR
NT seq 1020 nt   +upstreamnt  +downstreamnt
atgaaactagctgttattggtggcgatggcattggcccagaggttactgcagaagctctg
aaggtgctcaatgcggtacgcgatgacattgaagtcaccgattatgacctcggcgcacgc
cgttacctgcgcaacggtgaacttctcgcagatgctgatttggtatctttgcgcgaacat
gatgctattttgctgggggcaatcggggcaccaggcgaggttccaccaggagtgttggag
cgtggattgctgttgaaaatgcgcttcgcattggatcatcatgtgaatctgcgaccttct
aagctgtatcccacagcgacgtcgccgttggctaatcctggcgatatcgattttgtggtg
gtccgtgagggtactgagggtctttattgtggcaatggcggtactttgcgtgaggggacg
ccgcatgaaatagcgtcggaggtttcccaaaacactcgctacggtgtggaacgagttgtg
cgcgatgcttttgagcgcgctcaaaaccgcaaaaagcaccttacgctggtgcataaaacc
aatgttcttgttaatgctggtggtttgtggcagcgtaccgtcaatgagattgccactgag
tatccagaggttacagtcgattacaaccacattgatgctgcaactatttatatggtcacg
gaccccagtcgctatgacgttattgtgaccgataatttgtttggagacatcctcaccgac
cttgctggtgcggtaacgggtggtatcggtttagcggcttcgggcaacattgatgccact
ggtgtgaatccttcaatgtttgagcctgttcatggttcggccccagacattgcgggtcag
gggattgctgatcctactgctgctattttgtcggcggcgatgttactgcgtcatgtgggc
gatgagtctaatgcccagcgcattgaagcggcggtaacctatgatgttgcagagcggcct
gctggaccggttaagactgtcgaggtgggtgatcggatcgttgctgcattgcaacggtaa

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