KEGG   Caenorhabditis elegans (nematode): CELE_C05E4.9
Entry
CELE_C05E4.9      CDS       T00019                                 
Symbol
icl-1
Name
(RefSeq) Malate synthase
  KO
K01637  isocitrate lyase [EC:4.1.3.1]
K01638  malate synthase [EC:2.3.3.9]
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
cel00620  Pyruvate metabolism
cel00630  Glyoxylate and dicarboxylate metabolism
cel01100  Metabolic pathways
cel01200  Carbon metabolism
Module
cel_M00012  Glyoxylate cycle
Brite
KEGG Orthology (KO) [BR:cel00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CELE_C05E4.9 (icl-1)
   00630 Glyoxylate and dicarboxylate metabolism
    CELE_C05E4.9 (icl-1)
Enzymes [BR:cel01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.9  malate synthase
     CELE_C05E4.9 (icl-1)
 4. Lyases
  4.1  Carbon-carbon lyases
   4.1.3  Oxo-acid-lyases
    4.1.3.1  isocitrate lyase
     CELE_C05E4.9 (icl-1)
SSDB
Motif
Pfam: ICL MS_TIM-barrel MS_C PEP_mutase MS_N HpcH_HpaI Abi_C
Other DBs
NCBI-GeneID: 178583
NCBI-ProteinID: NP_503306
WormBase: WBGene00001564
UniProt: Q10663
Position
V:complement(724332..728004)
AA seq 968 aa
MSSAAKNFYQVVKSAPKGRFKGIKRDYTVEDVLKLRGSIDIDYTLATRGANKLWQLLHTE
PFVPALGAQTGNQAVQMVRAGLKAIYLSGWQVAADANSAGDMYPDQSLYPANSGPELAKR
INRSLRRADQIEACEAEDYLAQRDWYAPIVADAEAGFGGALNCFELMKAYIEAGAAGVHY
EDQLGSEKKCGHMGGKVLIPTAQHIRHLNASRLAADVCGVPTIIVARTDAESSRLLTSDI
DPRDHPYIDYEAGRTIEGFYRLKDSTAIQYCIDRAIQYAPYTDLIWMETSHPTIADAREF
AEGVHKQYPDKMFAYNCSPSFNWKKHLSPSQMEKFQKELGAMGFKYQFITLAGYHANSYS
MFDLARNYKEKGMLAYSGLQEGEFAAEKHGYTAVKHQREVGTGYFDAVSRAVTGGLSSTT
ALSGSTEEAQFQTAVASQDEEILSLTAQNVAGDEKILTPDALRFLHDLNTEFNPRRLRLL
SKRNQVQADINNSLWFPDFNKETEVLRSDQGWKGAEIPRDLQDRRVEITGPTDRKMVINA
MNSGANVFMADFEDSNSPTWRNQLEGQINLYDAVRNNISYTHPTTKKEYTLNEKHAVLKV
RPRGWHLPEKHVLIHNQPTSGSLFDFGLFVFHNAKALIAQGSGPYFYLPKLQSAEEAQLW
ADVFKYTEDKLGLARGTIKCTVLIEHLLASFQLHEIIHALKDNIVGLNCGRWDYIFSYIK
TFQNHRKFLLPDRFQIGMTAPFMRNYSLEVIKACHLRGIHAMGGMAAQIPIKHDQVANDK
AFALVRADKEREATDGHDGTWVAHPGLVPLAKRVFDQMMPKPNQISKNLTRANCTKEDLT
VIPEGTRTEAGFRHNISVTLGYLDSWLRGTGCVPLYNLMEDAATAEISRAQLWQWLHHDA
KLEDGRTIDAGLVKQTIAAETERRLIRAGSVVNRIPEAADLLEKFVTEEKMSDFLTTDAY
DRLVSEGY
NT seq 2907 nt   +upstreamnt  +downstreamnt
atgagttctgcggctaaaaatttttatcaggtagtcaaatcggctccaaaaggccgcttc
aagggcatcaaacgtgactataccgtcgaagatgtgctcaaactccgaggctccatcgac
attgactacacccttgccacacgtggagccaacaaactctggcaactattgcacactgag
ccatttgtgccggctctcggagcccagactggaaaccaagcagttcagatggtcagagcc
ggattgaaggctatctacttgtccggatggcaggtggctgccgacgcaaactccgctgga
gacatgtaccccgatcagtctttatatccagcaaactctggcccggaattggcgaagaga
atcaacagatctttaagaagagcagaccagattgaagcctgtgaagccgaggactacctc
gcccaacgtgattggtacgcgccaatcgttgccgatgcagaagccggattcggtggagcc
ctgaattgcttcgagttgatgaaggcctatatcgaagccggtgcggcaggagttcactac
gaagatcagcttggatcggagaaaaaatgtggtcatatgggaggaaaagtcttgatccca
accgcccaacacattcgtcacttgaatgcgtctcgtttggctgctgatgtctgcggagtt
cctacaatcattgtcgcaagaaccgacgcagagtcctctagacttttgacatctgacatt
gatccaagagatcatccatacattgactacgaggctggaagaacgattgaaggattctac
agactcaaggattccactgcaattcagtattgtatcgatcgtgccatccaatatgctcca
tacaccgatctcatctggatggagacctctcacccaacgatcgccgacgcccgtgaattc
gctgaaggtgtccacaagcagtacccagacaagatgttcgcctacaactgctctccatcc
ttcaactggaagaagcatctgtccccatcgcagatggagaagttccagaaggagttggga
gctatgggattcaaatatcagtttatcacgcttgccggataccatgccaacagttatagc
atgtttgacttggccagaaactacaaggagaagggtatgctcgcctattccgggctccag
gaaggagagtttgctgctgagaagcatggatatacggcagtaaagcatcagagagaagtg
ggaaccggatacttcgacgctgtcagtcgtgcggttaccggaggactctcttcgactact
gccttgtcaggatccactgaagaagctcaattccagactgctgttgcttcgcaggatgag
gaaatcctttcgctcaccgcccaaaacgttgctggagacgagaagatcctcacaccagat
gctcttcgcttcctccacgacctcaacaccgaattcaaccctcgccgtttgagacttctc
tccaagcgcaaccaagttcaggctgatatcaacaactccctctggttcccagatttcaac
aaggagaccgaggtgctccgtagtgatcaaggatggaagggagccgagattccaagggat
ttgcaagatcgtagagttgagatcactggaccaaccgatcgtaagatggttattaatgct
atgaactctggagccaatgtatttatggctgacttcgaagattccaactccccaacatgg
agaaaccagcttgaaggacagatcaacttatatgatgctgtaagaaataacatctcctac
acccacccaactactaagaaggagtacacactgaatgagaaacacgccgttctgaaggtc
cgtccacgtggatggcaccttccagagaagcatgtcctcatccacaaccagccaacttca
ggatctctctttgatttcggactcttcgttttccacaatgccaaggccctcatcgcccag
ggctccggtccatatttctatcttccaaagcttcaaagcgccgaggaggctcaactctgg
gctgacgttttcaagtacaccgaggacaagctaggcctcgcccgtggaaccatcaagtgt
accgtgctcattgagcatttgctcgccagcttccaactccacgagatcatccatgccctc
aaggacaacattgtcggactcaactgcggacgttgggattacatcttctcctacatcaag
acgttccagaaccatcgcaagttccttctcccagaccgattccaaattggaatgaccgct
ccattcatgagaaactactccttggaagtcatcaaggcctgccatctccgtggtatccat
gccatgggaggtatggctgcccagattccaatcaagcacgaccaggtcgccaatgacaag
gcatttgccctagtcagagctgacaaggaacgagaggccactgacggacacgatggaaca
tgggttgctcatccaggattggtgccattggctaagagagttttcgatcaaatgatgcca
aagccaaaccagatcagcaagaatctcacccgcgccaattgcaccaaggaagacctcact
gtgatcccagagggaacccgcactgaagctggattccgccataatatctctgtaactctt
ggatacctcgactcttggctcagaggaaccggatgcgtgccactctacaacttgatggag
gacgctgccaccgccgaaatctcgcgtgctcagctctggcaatggctccatcatgatgct
aagcttgaggacggtcgcactattgacgccggacttgtcaagcaaacgattgccgccgag
accgagcgtcgtctcatccgagccggatcagttgtcaaccgaatcccagaggctgccgac
ttgctcgagaagtttgtcaccgaggagaagatgagcgacttcttgaccaccgacgcttac
gacaggcttgtctctgaaggatattag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (4)   
   KEGG ENZYME (2)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (16)   
   KEGG ORTHOLOGY (2)   
   RefGene (10)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   WORMBASE (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (7)   
   Pfam (7)   
All databases (48)   

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