KEGG   Caenorhabditis elegans (nematode): CELE_T05H10.6
Entry
CELE_T05H10.6     CDS       T00019                                 
Symbol
pdha-1
Name
(RefSeq) Pyruvate dehydrogenase E1 component subunit alpha
  KO
K00161  pyruvate dehydrogenase E1 component subunit alpha [EC:1.2.4.1]
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
cel00010  Glycolysis / Gluconeogenesis
cel00020  Citrate cycle (TCA cycle)
cel00620  Pyruvate metabolism
cel00785  Lipoic acid metabolism
cel01100  Metabolic pathways
cel01200  Carbon metabolism
cel01210  2-Oxocarboxylic acid metabolism
Module
cel_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:cel00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    CELE_T05H10.6 (pdha-1)
   00020 Citrate cycle (TCA cycle)
    CELE_T05H10.6 (pdha-1)
   00620 Pyruvate metabolism
    CELE_T05H10.6 (pdha-1)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    CELE_T05H10.6 (pdha-1)
Enzymes [BR:cel01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.1  pyruvate dehydrogenase (acetyl-transferring)
     CELE_T05H10.6 (pdha-1)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C
Other DBs
NCBI-GeneID: 3565996
NCBI-ProteinID: NP_871953
WormBase: WBGene00011510
Ensembl: WBGene00011510
UniProt: Q8I111
Position
II:8066287..>8068184
AA seq 414 aa
MTKFLSLVHLERIWSTAMSLFARQLQSLTASGIRTQQVRLASTEVSFHTKPCKLHKLDNG
PNTSVTLNREDALKYYRDMQVIRRMESAAGNLYKEKKIRGFCHLYSGQEACAVGMKAAMT
EGDAVITAYRCHGWTWLLGATVTEVLAELTGRVAGNVHGKGGSMHMYTKNFYGGNGIVGA
QQPLGAGVALAMKYREQKNVCVTLYGDGAANQGQLFEATNMAKLWDLPVLFVCENNGFGM
GTTAERSSASTEYYTRGDYVPGIWVDGMDILAVREATKWAKEYCDSGKGPLMMEMATYRY
HGHSMSDPGTSYRTREEIQEVRKTRDPITGFKDRIITSSLATEEELKAIDKEVRKEVDEA
LKIATSDGVLPPEALYADIYHNTPAQEIRGATIDETIVQPFKTSADVLKSIGRA
NT seq 1245 nt   +upstreamnt  +downstreamnt
atgactaaatttcttagcttggtacatctggaacgtatttggtcgacggcaatgtcttta
ttcgcgagacaacttcaatccttgactgccagtggaatccgcacacagcaagttcgtctt
gcgagcacggaagtatcattccacacaaagccatgcaaacttcataaacttgacaatgga
ccaaacacctctgtcaccttgaacagagaagatgctctcaagtactaccgtgacatgcag
gtcattcgtcgcatggagtctgctgctggaaacttgtacaaggagaagaaaatccgcggt
ttctgtcatctctactctggtcaagaagcttgtgccgtcggaatgaaggctgcaatgaca
gaaggagatgccgtcatcactgcttaccgttgtcacggatggacctggcttcttggagct
accgtaaccgaggttcttgctgaattgaccggtagagttgccggaaatgttcacggaaaa
ggaggatccatgcatatgtacacaaagaatttctatggaggaaacggaattgttggagca
caacagccacttggagctggagttgcattggccatgaaataccgtgaacaaaagaatgta
tgtgttactttgtatggtgatggtgccgctaatcaaggacaacttttcgaggcgactaac
atggctaaactttgggatcttcctgttctgttcgtttgcgaaaacaatggattcggaatg
ggaactactgctgaacgttcatctgcttctaccgagtattatactagaggagactatgtt
cctggaatctgggttgatggtatggacattctcgctgttcgcgaggctaccaagtgggct
aaggaatattgtgacagtggtaaaggaccacttatgatggaaatggccacctatagatac
catggacactctatgtctgacccaggaaccagctaccgtacccgtgaagagattcaagaa
gttcgtaaaacaagagacccaattactggattcaaggaccgtatcattacatcttcattg
gccacagaggaagaacttaaggctattgacaaggaagttcgcaaagaggtcgatgaagcg
ttgaagattgctacatcagacggtgttctcccaccagaagctctctacgccgatatttat
cacaacaccccagctcaagagattcgcggagccactattgatgaaactatcgtccagcca
ttcaaaacttctgctgatgtactgaagtctattggaagagcttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (7)   
   KEGG MODULE (1)   
Chemical substance (11)   
   KEGG COMPOUND (11)   
Chemical reaction (5)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (130)   
   KEGG ORTHOLOGY (1)   
   RefGene (124)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   WORMBASE (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (3)   
   Pfam (3)   
All databases (165)   

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