KEGG   Caenorhabditis elegans (nematode): CELE_F31B12.1
Entry
CELE_F31B12.1     CDS       T00019                                 
Symbol
plc-1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
cel00562  Inositol phosphate metabolism
cel01100  Metabolic pathways
cel04020  Calcium signaling pathway
cel04070  Phosphatidylinositol signaling system
Module
cel_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cel00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    CELE_F31B12.1 (plc-1)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    CELE_F31B12.1 (plc-1)
   04070 Phosphatidylinositol signaling system
    CELE_F31B12.1 (plc-1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cel04131]
    CELE_F31B12.1 (plc-1)
Enzymes [BR:cel01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     CELE_F31B12.1 (plc-1)
Membrane trafficking [BR:cel04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    CELE_F31B12.1 (plc-1)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    CELE_F31B12.1 (plc-1)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RasGEF RA EF-hand_like C2 PH_12
Other DBs
NCBI-GeneID: 181274
NCBI-ProteinID: NP_001024619
WormBase: WBGene00004036
Ensembl: WBGene00004036
UniProt: G5EFI8
Position
X:complement(<10794857..>10838650)
AA seq 1895 aa
MNWDTLKGVLKTRRLTKRTIPAYIHPTSRSDSTSSTQSATAGFILNEEPITLFRLELERL
QYILHFPEEVAFQLSSTEYQLFYSIQPMDYVRYVSCDLTSVPVSENPSPVRNLVKRLSEV
SSWITHVIVSQPTHDDRKVALTAILRIVETCWNIGNFNAAVEVLMGLKSEKLRPFWLSLR
QEEKSQFDSLCETLLPANQALPSQAYINAVQRALRMPQSRVIPFFGIFLRDLYAIVNDLP
NIVVIGQEGETQKLEFMSDPNGEDHFSSRIGVGGLLNADKINLVAIVLDNLELFHRHSRT
MIKLLEEQAVPPIQIPQNEREQKEKEAKTYEPVQVVRGSSHGVALIPLDTLTFDLDVIQR
LQHGTTVIHYEPDSGRSNLCLLRLDPSCGQINWHKISYSVNKDPKEKDVLAKVSVSNLQP
LDSGRGAPSPMPSGRTPGTGGVGVEEGELKLSVVKGVELVDSYDIDIEAIYRRHSMEEMS
VPVSCWKVSHGQLLSDNEFIYFLAPQQIAQFWTNGLQSVVKSLQGQQRYPDRRMLWIKNV
YLSLYEITGESNCGPRPFEALQAFGLSQTNTNATRPNDSSLSSEPGGAKSRLKNLKNAMQ
KKLRGASREGSRSQSPQPHSPLVRPPSIKSQISSQSGPPGPNSPGYLLKPRGEPANSDAG
DIDSIYTPRSRTPTSSSYGGRSVGGRSCKSWRSRGGETPNSGSISSSGQMSIQVSGLSGP
SGKEFQEKPLTLVEFAELFRLFNTRMRKDLRDVFNDVLSTATTPQHCPKRERDRHSPRMQ
SRLASVSNSYNADFLSNDFLTRNTAVTSHHISEKQNKIYNALALASVNSMGGLMDTSRSS
MLTPQMLRAFVNTHQMEQIDEQTAIKLIQDHEPDGICRQKNQMSFEGFTRFLCDPVNFAF
VPETIEPDEEDLRYPLSHYYINSSHNTYLTGHQLKGPSSSEMYRQVLLTGCRCVELDCWD
GDDGLPLIYHGHTLVSKIGFRQVVEIIKKSAFITSDLPVILSIENHCSLQQQAKMAQMFK
TVLGDLLVSNFLFEADFSDSPRLPCPLQMKNKILIKNKKMIVDPPTPLPMIERGAVQRGE
TQLNLHRKQSKNSYESSTVDEVEDDDLDEFLDDEENEEDDQEEVQVRSEKEDSPKTSKRA
EKSARNIKQQDSLCSDHSVEQAKPSTSKTTSKTNDRKTEDEVLYAQLAQNAIRNQQPRKN
NTGVQIAPELSDIVIYMQATKFKGFPPVDGIQSPRIMEEGPASASLSFSSRARTPSNLLN
TPAPPRRQRSSTQLSQELAAEFLGSVRANATATCYQVTSLNENAAKKLMKRHPAKCVSYT
RDHLIRTYPSAKHYDSSNFNPINCWAHGMQMVALNFQTPDVIMAVNQAMFEQSGNCGYQL
KPRCLWDESHLLYNKFLPLSKDIAGHSALLLNLTIISGQHVYPNTHYASLYVEIEVIGIH
NDCVREKSKVVQRNSVNPIWNHTTQLRIACVDLAFLRIAVCDSGQNGRVVAHRVVPVKCI
RPGFRHLPLRTPTNLPIDNAMIFLRTRFEQEEHIYLHDDDSNTYCNLEHTLAYRTDLTPN
LSPTPILKKQIFVLRITGAFADETAITVHSESGSTVKTVMQQALLNAGKNADQVEEYVLI
EESLPAPSGEDPIEQRVLPLNEPIMDAVACWNGSMRRFVLRKKGSDPSSRAWITSIIKSG
TSGSSTSVSPSPLTKDGHVKSASSNQLHGRSLDTDAFGEHLEVTEGKWLNPRARSMGDTF
LVCVHNVSEDQPYAILRAGIHSTAADIIRQVFVKARRSNVDDSEFVLVEETCDDPKLNQG
QMTPKYPNNRTTSRVLGQNENVWKAQSRWKSMGRFVLENRKDTVHATLEKGRRVESTTSS
STTTRKISLSSVRSIGLPRKFSKFGKSLTMDAGPK
NT seq 5688 nt   +upstreamnt  +downstreamnt
atgaactgggacactctgaaaggcgtgctgaaaacaaggcgtttgacaaaacgtacgatt
ccagcgtatattcatccaacatcacgtagtgactcaacctcttcaacgcaatcagccaca
gctggattcattctcaatgaagaaccaatcacactgttccgacttgaactcgaacgactt
caatatattcttcatttccctgaagaagttgcattccaactatcttctactgagtatcag
cttttctactcaatacaacccatggattatgttcgttacgtcagttgcgatctcacatct
gttccagtgtcagaaaatccaagtccagtgcgaaatcttgtgaaaaggctatcagaggta
tcatcctggataacacatgttattgtcagtcagccaacacatgacgatcgaaaggttgct
cttactgcaattttgagaattgtggaaacttgctggaatattggaaactttaatgcagct
gttgaggttcttatgggtttaaagagtgaaaaactcagaccattctggctttctttgcga
caagaggaaaagtctcagtttgattcgctttgcgaaaccttgcttcctgcaaaccaagct
ctcccatctcaagcttacatcaacgcggtccaacgagcactgagaatgccacaatctcgt
gtgattccattttttggaatatttcttcgtgatctctacgcaattgtgaatgacttgccg
aatatcgttgtgattggacaagaaggtgaaacccaaaagctggaattcatgagcgatccc
aatggcgaagatcatttttcgtcgagaattggagtgggtgggctgttgaatgctgataaa
atcaacttggtggcaattgttttggacaacttggaattattccatcgtcacagcaggaca
atgatcaaattgttagaagagcaagcagtcccaccaattcaaattcctcagaacgagcgg
gagcaaaaagaaaaggaagcaaaaacatatgaaccagtacaagtggttcgcggctcttct
catggagtggctctcatccctcttgataccctaacattcgatcttgatgttatccaacga
ctccagcacggaacaacagtgatccattacgaacctgattcgggaagaagcaatttgtgt
ctgctgcggttagaccctagttgcggtcaaataaactggcataagatttcatattcagtt
aacaaagatcccaaagaaaaggatgtgctcgccaaagtatccgtttcaaatctgcagccg
ctagactctggccgaggggctccgtcaccaatgccatctggaagaacaccaggaactgga
ggagttggagtagaggagggagaactcaaattaagtgttgtgaaaggagtcgaactagtt
gatagttatgatattgatattgaggcaatttaccgtcgtcattctatggaagagatgtca
gttcctgttagctgttggaaagttagtcatggtcagttgttatcggataatgagttcatc
tactttttggcccctcaacaaattgctcaattttggaccaacgggttgcaatctgtagtt
aaaagtctccaaggacagcaaaggtaccctgatcggcgaatgttatggatcaaaaatgtc
tacttatcactttacgagataacgggcgaatcaaactgtggaccacggccatttgaagca
cttcaggcatttgggctgagtcaaacaaatactaacgcaacacgacccaatgactcgtcg
ctgtccagtgagccaggaggagctaaaagcagactgaagaaccttaaaaatgctatgcaa
aagaagcttcgtggtgcatcgcgcgaaggaagcagatctcagtcacctcaacctcattct
cctcttgtccgaccaccatcaataaaatcgcaaatatcgtcacaatctggtccgccgggt
ccgaactctccaggctatttgctgaaaccacgtggagaacctgccaatagtgatgcagga
gacattgatagcatttatacacctcgatcaagaactccaacaagcagctcctatggaggg
cgatccgttggagggagatcatgtaaatcgtggagatcaagaggaggagagacaccaaat
tcgggttccataagcagctcgggtcagatgtcaattcaagtgtctggtctgagtggacca
tcgggaaaagagtttcaggaaaaaccattaacacttgtagagttcgctgaactttttcga
ttgttcaatacaagaatgagaaaagatttgagagatgtgttcaatgatgtcctgtctacg
gcaactactcctcagcattgtcctaaaagagaacgtgatcgccacagtccgagaatgcag
tcaaggctggcgagtgtctccaactcgtacaatgcagattttctgtctaacgatttcttg
actcggaatacggcagtaacgtcccatcatatcagtgaaaagcaaaacaaaatctacaat
gcattggcacttgcgagtgttaatagcatgggcggactcatggacacttcccggtcgtcg
atgctgacgccgcaaatgctgcgcgcttttgtcaacactcatcagatggagcagattgac
gagcaaacggcgattaagcttattcaggatcatgaacctgatggtatctgtcgacaaaag
aatcaaatgtcattcgaaggattcactagattcctttgcgatcctgtcaactttgcattc
gtaccggaaacaattgaaccagatgaagaggacctacggtacccgttgtctcattattac
atcaattcaagtcacaacacctatttgacgggacatcaactcaagggacccagtagctcg
gagatgtacagacaggttctcctcaccgggtgtcggtgtgtcgagcttgattgttgggat
ggagatgacggattgccattgatttatcatggacacacattggttagcaagattgggttt
agacaggtggtcgaaattatcaaaaaatctgcattcataacatcggatcttcctgtgata
ttatcaattgagaatcattgttccctacaacaacaggcgaaaatggcacagatgttcaaa
acagttcttggagatttactagtatcaaacttcctttttgaagctgatttctcggactct
ccacgtcttccatgccctctccaaatgaaaaataagatcttgataaaaaataagaaaatg
atagtcgacccaccaactccattgccaatgattgaacgaggagctgtgcagcgtggtgaa
actcaattaaatcttcacagaaaacagagtaaaaactcctacgaaagcagtacggtagat
gaagtggaagatgacgacctagatgagtttcttgacgatgaagaaaatgaggaggatgac
caagaagaggttcaagtcagaagtgaaaaagaagacagtccgaagacatcaaaacgtgca
gagaaatcggctagaaacatcaaacagcaagattcgttatgtagcgatcattcggtagag
caggcaaaaccttccacaagcaagaccacatccaaaaccaacgatagaaagactgaagat
gaagtactttacgctcaacttgctcaaaatgccatccgaaaccaacaaccaagaaagaac
aatactggagtccaaatagcgccagagttgtcagatattgtcatttacatgcaagcgaca
aaattcaaaggatttcccccagtcgatggcattcaatcaccaaggataatggaggaaggg
ccagcttctgcaagtctttcattttcatcacgggctcgtacgccatcaaatctgctgaat
acaccagcccctccacgacgacagcgaagtagcactcagttgagtcaagaactggctgca
gaatttttgggatcagttagggcaaatgctacagctacatgctaccaggttacatctctt
aatgaaaacgctgcaaagaaactgatgaaaagacatccagcaaaatgcgtatcttatact
cgggaccatctgattcgtacgtatccaagtgccaagcactatgactcgtccaactttaac
cccatcaactgctgggctcatggaatgcaaatggttgctttaaattttcaaactcctgat
gttataatggcagttaaccaagcgatgttcgagcaatctggaaactgtggatatcaactg
aaaccacgttgtctttgggatgaatctcatcttttgtacaacaaatttttgcctctctcc
aaagacattgccggccattctgctttgttactaaacttaactattatatccggacagcac
gtgtatccaaacacccattacgccagtttatatgtcgaaattgaagtcatcggtattcac
aacgactgtgttcgtgagaaatcaaaagtggtccagagaaattctgtgaatccaatctgg
aaccacaccactcaacttcgaatagcttgtgttgacttagcattccttcgcatagcagta
tgtgatagtgggcaaaatggaagagtcgttgctcaccgagttgttcctgtcaaatgcatt
cgtccgggtttccgacatctcccactcagaactccaactaatcttccgatcgacaacgct
atgatatttttaagaacaagattcgagcaagaagaacacatctacctccacgacgatgat
tcaaacacctattgtaatctagaacatacgctggcataccgcacagacttaacacccaat
ttatctccaacgccaattttgaagaaacagatctttgttcttcgaattacaggcgcgttt
gctgatgaaacagcaattacagtgcacagcgagtcaggaagtacagtgaagacggtgatg
caacaggcgctgcttaacgctggaaagaatgcggatcaggttgaagagtatgtactcatc
gaagaatcactgccggcaccttctggggaagatccaattgagcagagagtacttcctctg
aacgagcctatcatggacgccgtggcctgctggaacggttcaatgcgtcgttttgtgtta
cgaaaaaaaggcagtgacccatcatctagagcttggatcacttcaattataaaatccgga
acaagtggaagctccacgtcagtctcaccaagtccgttgaccaaagatggacacgtaaag
agtgcatcaagcaatcaacttcatggacgatcattggacactgacgcttttggagagcac
cttgaagtgacagaaggcaagtggttgaaccctcgtgcaagatcaatgggcgacacattt
ctggtatgtgttcacaatgttagtgaagatcagccttatgcaatcctacgtgctggaatc
cacagcactgccgccgacattattcgtcaggtgtttgttaaagctcgccgttcaaatgta
gacgattccgagtttgttcttgttgaagaaacctgcgatgatccaaaactcaatcaaggc
caaatgactccaaagtatccaaacaaccgcaccacaagccgagtgttaggacaaaacgaa
aatgtttggaaagcacaatcgaggtggaagtcaatgggcagatttgtacttgaaaaccga
aaggacacagtgcacgcaaccctcgaaaaaggtagacgtgtggaaagcacaacttcttcc
tccaccacaacgcgcaaaataagtttatccagcgttcgctcaatcggtcttccacgtaaa
ttctccaagtttggcaagtcgttgactatggatgctggaccaaagtga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (51)   
   KEGG ORTHOLOGY (1)   
   RefGene (45)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   WORMBASE (1)   
Protein sequence (14)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (12)   
DNA sequence (12)   
   RefSeq(nuc) (12)   
Protein domain (7)   
   Pfam (7)   
All databases (105)   

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