KEGG   Caenorhabditis elegans (nematode): CELE_R05G6.8
Entry
CELE_R05G6.8      CDS       T00019                                 
Symbol
plc-4
Name
(RefSeq) Phosphoinositide phospholipase C
  KO
K05857  phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Organism
cel  Caenorhabditis elegans (nematode)
Pathway
cel00562  Inositol phosphate metabolism
cel01100  Metabolic pathways
cel04020  Calcium signaling pathway
cel04070  Phosphatidylinositol signaling system
Module
cel_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:cel00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    CELE_R05G6.8 (plc-4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    CELE_R05G6.8 (plc-4)
   04070 Phosphatidylinositol signaling system
    CELE_R05G6.8 (plc-4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cel04131]
    CELE_R05G6.8 (plc-4)
Enzymes [BR:cel01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     CELE_R05G6.8 (plc-4)
Membrane trafficking [BR:cel04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    CELE_R05G6.8 (plc-4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    CELE_R05G6.8 (plc-4)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y C2 EF-hand_10 EF-hand_like EF-hand_7 EF-hand_6 EF-hand_5 EF-hand_1 PH PH_12 GDPD
Other DBs
NCBI-GeneID: 177525
NCBI-ProteinID: NP_501213
WormBase: WBGene00004039
Ensembl: WBGene00004039
UniProt: Q21754
Position
IV:complement(7509524..7512667)
AA seq 751 aa
MAKSVSPEEQAAAQAADEEKTKEELEWAEKGSLLCRIKNQKVKEMALVTIKSKQFLNYYS
SYWFNFVPNALKSVALSELLEVRSGYQTDNLQRASKKYEFQELAPESRCFSVIFSHAKFL
HKSVDFSADSKETRDKWVSVLTHLISVAKHQRVVFNETAWLIDKFQQADTNKNGLLSFDE
VWNLLKRMNLQISERYAKAIFRESEFENSRDNKLNEKEFLNFFERLTDRPDLRFVMTQAS
SDNVETLTVADLQRFLTEEQGFENVDLKKAEQILTTFEQTVQDKQKEKLMGLMGMRRLMQ
SRWGNVFKPGHESIFQDMDQPLTHYFVNSSHNTYLTGLQVKGEATVEGYISALRKGARLL
ELDLFDGEHGEPVITHKRTFIESITLRNSLEAIKRTAFETSPYPVILTLENHVGFVQQAV
MADLFKEILGDSLYIPPKDSHRHPLSSPNKLKRKFLLRGKKIILEEDIEEPDEDDSPTDK
DKHHVHPHPVAPELSALIGLPSVKLSHNIYQDVNKHPFDGSPSLSENKVYTMFEAAVPIF
TYTAERLVKSYPKGLRQDSSNMHPMVSWLCGIQSVAMNFQTAGEELDLNAGLFRINGNCG
YVLKPSCLLDGVDPRSMAKPKLKLGIGLFSAQYLPKSEPGKEIIDPYVSVQIFGIPRDET
KAKTRIIKDNGFNPEWRDNFYFTLSCPELAIIRFCVKDFDSTSSNDFVGEFSIPVMSLRT
GFSQIQLNTGYQHTLDPSASLFVRIAMEEEY
NT seq 2256 nt   +upstreamnt  +downstreamnt
atggccaagagcgtatccccagaggagcaggccgccgcacaagctgctgatgaagagaag
acgaaagaagaattagaatgggctgaaaaaggatcgcttttatgtagaattaaaaatcaa
aaagtgaaggaaatggcgttggtgacaataaaaagtaaacaattcctcaactattactca
agttattggtttaattttgtgccaaatgctttgaaatcagttgcactatcggaattgtta
gaagttcgatcgggttatcaaactgacaatctgcaaagagcatcgaaaaaatacgaattc
caagagttggctccagagtctagatgtttctccgttattttttctcatgccaagttcttg
cacaaatcagtagatttcagtgctgattccaaagaaactagagacaaatgggtttccgta
ctgacacatctcatatcagttgccaaacatcaaagagttgtattcaacgaaacagcatgg
ttgattgacaaatttcaacaggcggataccaataaaaacggacttcttagttttgacgaa
gtttggaatcttcttaaacgaatgaatcttcaaataagtgaacgatatgcaaaagcgata
ttcagagaatcagagtttgagaactcgcgagataataaattgaacgagaaagaatttctt
aacttttttgaaagattgactgatcgaccggatcttcgatttgtgatgactcaagcaagt
tctgataacgtggaaacgctgactgttgctgatttgcaaagatttttaactgaagaacaa
ggattcgaaaatgttgatttgaaaaaagccgaacaaattctgactacatttgaacaaact
gttcaagataagcaaaaagaaaaattgatgggattgatgggaatgcgtcgattaatgcag
tcaagatggggaaatgtattcaaaccaggacatgaaagtatcttccaagatatggatcaa
cctctgactcattattttgttaattcatcacataacacatatttgactggcttgcaagtg
aaaggagaagctactgttgaaggttatatttcagctttacgtaaaggagcaaggctttta
gaattagacttgtttgatggcgaacacggagagccagtaatcacacataaaagaaccttt
atcgagtcgattacattgaggaattcgctggaagctattaagagaactgcgtttgaaaca
tcaccatatcctgtcatcctcaccctcgaaaaccacgtcggatttgtacaacaggctgtt
atggcagatttattcaaagaaattcttggagattctttatatattccaccaaaagattca
catcgccatccgttatcatctccgaataagctgaaaagaaaattcctattgcgcggaaag
aaaattattcttgaagaagacattgaagaaccagatgaagatgattcaccaactgataag
gataagcaccatgtacatccacatccagttgcacctgaattatcagctctcattggtttg
ccgtcagtaaaattgagccataatatttatcaagacgtcaacaaacatccatttgatgga
agtccttcgctctcggaaaataaagtatatacaatgtttgaagctgcagttcccatcttc
acttacactgcagaaaggcttgtgaagagttatccaaaaggattacgtcaagattcatca
aatatgcatccaatggtttcttggctttgtggaattcaaagtgttgctatgaacttccaa
accgctggtgaagagcttgatttgaatgcaggattattcagaattaatggaaattgcggt
tacgttctgaaaccaagttgccttctcgatggagtcgatccaagaagtatggccaaacca
aaattgaagcttggtattggacttttctctgctcagtatcttccaaagtcagaacccgga
aaagagatcattgatccatacgtcagtgttcagattttcggaattccacgagatgaaaca
aaagcaaaaacaagaatcatcaaggacaatggattcaacccagaatggagggataatttc
tatttcacactctcgtgcccagagctagcaattattcgattctgtgtaaaagattttgac
tctacatcttcgaacgactttgttggagaattctcaattcctgttatgagtcttcgtaca
ggtttctcgcaaattcaactaaataccggatatcaacatactctggacccatctgcatct
ctttttgtacgaattgcaatggaggaagagtactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (5)   
   KEGG PATHWAY (4)   
   KEGG MODULE (1)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (4)   
   KEGG ENZYME (1)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (22)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   WORMBASE (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (12)   
   Pfam (12)   
All databases (64)   

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