KEGG   Canis lupus familiaris (dog): 403954
Entry
403954            CDS       T01007                                 
Symbol
RHOA
Name
(RefSeq) transforming protein RhoA
  KO
K04513  Ras homolog gene family, member A
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04014  Ras signaling pathway
cfa04015  Rap1 signaling pathway
cfa04022  cGMP-PKG signaling pathway
cfa04024  cAMP signaling pathway
cfa04062  Chemokine signaling pathway
cfa04071  Sphingolipid signaling pathway
cfa04072  Phospholipase D signaling pathway
cfa04144  Endocytosis
cfa04150  mTOR signaling pathway
cfa04270  Vascular smooth muscle contraction
cfa04310  Wnt signaling pathway
cfa04350  TGF-beta signaling pathway
cfa04360  Axon guidance
cfa04510  Focal adhesion
cfa04520  Adherens junction
cfa04530  Tight junction
cfa04611  Platelet activation
cfa04621  NOD-like receptor signaling pathway
cfa04625  C-type lectin receptor signaling pathway
cfa04660  T cell receptor signaling pathway
cfa04670  Leukocyte transendothelial migration
cfa04722  Neurotrophin signaling pathway
cfa04810  Regulation of actin cytoskeleton
cfa04921  Oxytocin signaling pathway
cfa04928  Parathyroid hormone synthesis, secretion and action
cfa04972  Pancreatic secretion
cfa05100  Bacterial invasion of epithelial cells
cfa05132  Salmonella infection
cfa05133  Pertussis
cfa05135  Yersinia infection
cfa05152  Tuberculosis
cfa05163  Human cytomegalovirus infection
cfa05200  Pathways in cancer
cfa05203  Viral carcinogenesis
cfa05205  Proteoglycans in cancer
cfa05206  MicroRNAs in cancer
cfa05210  Colorectal cancer
cfa05417  Lipid and atherosclerosis
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    403954 (RHOA)
   04015 Rap1 signaling pathway
    403954 (RHOA)
   04310 Wnt signaling pathway
    403954 (RHOA)
   04350 TGF-beta signaling pathway
    403954 (RHOA)
   04072 Phospholipase D signaling pathway
    403954 (RHOA)
   04071 Sphingolipid signaling pathway
    403954 (RHOA)
   04024 cAMP signaling pathway
    403954 (RHOA)
   04022 cGMP-PKG signaling pathway
    403954 (RHOA)
   04150 mTOR signaling pathway
    403954 (RHOA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    403954 (RHOA)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    403954 (RHOA)
   04520 Adherens junction
    403954 (RHOA)
   04530 Tight junction
    403954 (RHOA)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    403954 (RHOA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    403954 (RHOA)
   04621 NOD-like receptor signaling pathway
    403954 (RHOA)
   04625 C-type lectin receptor signaling pathway
    403954 (RHOA)
   04660 T cell receptor signaling pathway
    403954 (RHOA)
   04670 Leukocyte transendothelial migration
    403954 (RHOA)
   04062 Chemokine signaling pathway
    403954 (RHOA)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    403954 (RHOA)
   04928 Parathyroid hormone synthesis, secretion and action
    403954 (RHOA)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    403954 (RHOA)
  09154 Digestive system
   04972 Pancreatic secretion
    403954 (RHOA)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    403954 (RHOA)
  09158 Development and regeneration
   04360 Axon guidance
    403954 (RHOA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    403954 (RHOA)
   05206 MicroRNAs in cancer
    403954 (RHOA)
   05205 Proteoglycans in cancer
    403954 (RHOA)
   05203 Viral carcinogenesis
    403954 (RHOA)
  09162 Cancer: specific types
   05210 Colorectal cancer
    403954 (RHOA)
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    403954 (RHOA)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    403954 (RHOA)
   05135 Yersinia infection
    403954 (RHOA)
   05133 Pertussis
    403954 (RHOA)
   05152 Tuberculosis
    403954 (RHOA)
   05100 Bacterial invasion of epithelial cells
    403954 (RHOA)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    403954 (RHOA)
   05418 Fluid shear stress and atherosclerosis
    403954 (RHOA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    403954 (RHOA)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    403954 (RHOA)
   04031 GTP-binding proteins [BR:cfa04031]
    403954 (RHOA)
Membrane trafficking [BR:cfa04131]
 Endocytosis
  Lipid raft mediated endocytosis
   RhoA-dependent endocytosis
    403954 (RHOA)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   403954 (RHOA)
  Exosomal proteins of other body fluids (saliva and urine)
   403954 (RHOA)
  Exosomal proteins of colorectal cancer cells
   403954 (RHOA)
  Exosomal proteins of bladder cancer cells
   403954 (RHOA)
GTP-binding proteins [BR:cfa04031]
 Small (monomeric) G-proteins
  Rho Family
   RhoA/B/C [OT]
    403954 (RHOA)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU Gtr1_RagA SRPRB VASP_tetra
Other DBs
NCBI-GeneID: 403954
NCBI-ProteinID: NP_001003273
Ensembl: ENSCAFG00000023066
VGNC: 81924
UniProt: A0A8C0T4F4 A0A8I3PVV6
Position
20:39743026..39805566
AA seq 193 aa
MAAIRKKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVFENYVADIEVDGKQVELALWDT
AGQEDYDRLRPLSYPDTDVILMCFSIDSPDSLENIPEKWTPEVKHFCPNVPIILVGNKKD
LRNDEHTRRELAKMKQEPVKPEEGRDMANRIGAFGYMECSAKTKDGVREVFEMATRAALQ
ARRGKKKSGCLVL
NT seq 582 nt   +upstreamnt  +downstreamnt
atggctgccatccggaagaaactggtgattgttggtgatggagcctgtggtaagacttgt
ttgctcatcgtctttagcaaggaccagttcccagaggtgtatgtacccacagtgtttgag
aactatgtggcagatattgaagttgatggaaagcaggtagagttggctttgtgggataca
gctgggcaggaagattatgatcgcttgaggcctctctcctatccagacactgatgttata
ctgatgtgtttctctattgacagccctgatagcttagaaaacatcccagaaaaatggacc
ccagaagtcaagcacttctgtcccaacgtgcccatcatcctggttgggaacaagaaggat
cttcggaatgatgagcacacaaggcgggagctagccaagatgaagcaggagccggtgaaa
ccggaagaaggcagagatatggcaaacaggattggtgcttttgggtacatggagtgttca
gcaaagaccaaagatggagtgagggaggtttttgaaatggccacgagagctgctctgcaa
gccagacgtgggaagaaaaaatctgggtgccttgtcttgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (39)   
   KEGG PATHWAY (39)   
Genome (1)   
   KEGG GENOME (1)   
Gene (49)   
   KEGG ORTHOLOGY (1)   
   RefGene (43)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (4)   
   UniProt (2)   
   RefSeq(pep) (2)   
DNA sequence (10)   
   RefSeq(nuc) (2)   
   GenBank (4)   
   EMBL (4)   
Protein domain (7)   
   Pfam (7)   
All databases (114)   

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