KEGG   Canis lupus familiaris (dog): 476713
Entry
476713            CDS       T01007                                 
Symbol
KEAP1
Name
(RefSeq) kelch-like ECH-associated protein 1
  KO
K10456  kelch-like protein 19
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04120  Ubiquitin mediated proteolysis
cfa05012  Parkinson disease
cfa05200  Pathways in cancer
cfa05208  Chemical carcinogenesis - reactive oxygen species
cfa05225  Hepatocellular carcinoma
cfa05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    476713 (KEAP1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    476713 (KEAP1)
   05208 Chemical carcinogenesis - reactive oxygen species
    476713 (KEAP1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    476713 (KEAP1)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    476713 (KEAP1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    476713 (KEAP1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:cfa04121]
    476713 (KEAP1)
Ubiquitin system [BR:cfa04121]
 Ubiquitin ligases (E3)
  Multi subunit Ring-finger type E3
   Cul3 complex
    Adoptor and target recognizing subunit (BTB)
     476713 (KEAP1)
SSDB
Motif
Pfam: Kelch_1 Kelch_6 Kelch_3 Kelch_2 BACK BTB Kelch_4 KLHL33-like_BTB_POZ
Other DBs
NCBI-GeneID: 476713
NCBI-ProteinID: XP_005632954
Ensembl: ENSCAFG00000017784
VGNC: 42332
UniProt: A0A8C0T754 A0A8I3PZ96
Position
20:50523052..50533206
AA seq 624 aa
MQPEPGPSGAGARTRFLPLRSQRPEGAGDTVMYASTECKAEVTPSQHGNRTFSYTLEDHT
KQAFGIMNELRLSQQLCDVTLQVKYEDAPAAQFMAHKVVLASSSPVFKAMFTNGLREQGM
EVVSIEGIHPKVMERLIEFAYTASISMGEKCVLHVMNGAVMYQIDSVVRACSDFLVQQLD
PSNAIGIANFAEQIGCAELHQRAREYIYMHFGEVAKQEEFFNLSHCQLVTLISRDDLNVR
CESEVFHACINWVKYDCEQRRFYVQALLRAVRCHSLTPHFLQMQLQKCEILQSDSRCKDY
LVKIFQELTLHKPTQVMPCRAPKVGRLIYTAGGYFRQSLSYLEAYNPSDGTWLRLADLQV
PRSGLAGCVVGGLLYAVGGRNNSPDGNTDSSALDCYNPMTNQWSPCASMSVPRNRIGVGV
IDGHIYAVGGSHGCIHHNSVERYEPERDEWHLVAPMLTRRIGVGVAVLNRLLYAVGGFDG
TNRLSSAECYYPERNEWRMITPMNTIRSGAGVCVLHNCIYAAGGYDGQDQLNSVERYDVE
TETWTFVAPMKHRRSALGITVHQGRIYVLGGYDGHTFLDSVECYDPDTDTWSEVTHMTSG
RSGVGVAVTMEPCRKQIDQQNCTC
NT seq 1875 nt   +upstreamnt  +downstreamnt
atgcagccggaacctgggcctagcggggctggggcccgcactcgattccttcccctgagg
tcacagcgccccgagggggcaggggacacggtgatgtacgcctccaccgagtgcaaagcc
gaggtgacgccctcccagcacggcaaccgcaccttcagctacacgctggaggaccacacc
aagcaggccttcggcatcatgaacgagctgcggctcagccagcagctgtgtgacgtcacg
ctgcaggtcaaatacgaggacgcgccagctgcccagttcatggctcacaaggtggtgctg
gcctcatccagccccgtcttcaaggccatgttcaccaatgggctacgggagcagggcatg
gaggtggtgtccattgagggcatccaccccaaggtcatggagcgcctaattgagtttgcc
tacacggcctccatctccatgggtgagaagtgcgtgctccacgtgatgaatggcgccgtc
atgtaccagatcgacagcgtcgtccgtgcctgcagtgacttcctcgtgcagcagctggac
cccagcaatgccattggcattgccaacttcgctgaacagatcggctgcgctgagctgcac
cagcgtgcccgcgagtacatctatatgcacttcggagaggtggccaagcaagaggagttc
ttcaacttgtcccattgccagctggtgactctcatcagccgagacgatctgaatgtgcgc
tgcgagtccgaggtcttccacgcctgtatcaactgggtcaagtatgattgtgagcagcgg
cgcttctatgtccaggcattgctccgggctgtgcgatgtcactcgctcacaccccacttc
ctgcagatgcagctgcagaagtgtgagatcttgcagtcggactcccgctgcaaggactac
ctggtcaagatcttccaggagctgaccttgcataagcccacgcaggtgatgccctgtcgg
gcgcccaaagtgggccggctcatctacaccgctggtggctacttccgccagtcactcagc
tacctagaggcctacaaccccagtgatggcacttggctccgattggcagacctgcaggtg
cctcgtagtggcctggcgggctgcgtagtgggtgggctgctgtatgctgtgggcggccgg
aacaactcgccagacggcaacaccgactccagcgccctggactgctataaccccatgacc
aaccagtggtcgccctgtgcctccatgagtgtaccacgcaatcggattggggttggggtc
attgatgggcacatctatgctgtcggtggctcccacggctgcatccaccacaacagtgtg
gagaggtatgagccagaacgggatgagtggcacttggtggctcccatgctgactcgaagg
atcggggtgggagtggctgtcctcaaccgtttgctctatgccgtcgggggctttgatgga
acaaaccgcctcagctcagcagagtgttactaccccgagagaaatgagtggcgaatgatc
acacccatgaacaccatccgaagtggggcaggagtctgtgtcctgcacaactgtatctat
gctgcggggggctatgatggtcaggaccagctgaacagcgtggagcgctatgatgtagag
acggaaacgtggacttttgtagctcccatgaagcatcggcgaagtgccctagggattact
gtgcaccagggaagaatctacgttctgggaggctacgatggccacacattcctggacagt
gtggagtgttatgacccagacacagacacctggagtgaggtgacccacatgacatccggc
cggagcggggtgggtgtcgctgtcaccatggaaccctgccggaagcagatcgaccagcag
aactgtacctgttga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (6)   
   KEGG PATHWAY (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (36)   
   KEGG ORTHOLOGY (1)   
   RefGene (30)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (11)   
   UniProt (2)   
   RefSeq(pep) (9)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (8)   
   Pfam (8)   
All databases (73)   

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