KEGG   Canis lupus familiaris (dog): 477120
Entry
477120            CDS       T01007                                 
Symbol
MME
Name
(RefSeq) neprilysin
  KO
K01389  neprilysin [EC:3.4.24.11]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04614  Renin-angiotensin system
cfa04640  Hematopoietic cell lineage
cfa04974  Protein digestion and absorption
cfa05010  Alzheimer disease
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    477120 (MME)
  09152 Endocrine system
   04614 Renin-angiotensin system
    477120 (MME)
  09154 Digestive system
   04974 Protein digestion and absorption
    477120 (MME)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    477120 (MME)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cfa01002]
    477120 (MME)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cfa04147]
    477120 (MME)
   04090 CD molecules [BR:cfa04090]
    477120 (MME)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.11  neprilysin
     477120 (MME)
Peptidases and inhibitors [BR:cfa01002]
 Metallo peptidases
  Family M13: neprilysin family
   477120 (MME)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   477120 (MME)
CD molecules [BR:cfa04090]
 Proteins
  477120 (MME)
SSDB
Motif
Pfam: Peptidase_M13_N Peptidase_M13
Other DBs
NCBI-GeneID: 477120
NCBI-ProteinID: NP_001275995
Ensembl: ENSCAFG00000008711
VGNC: 43271
UniProt: F5C3N2 A0A8C0T1M5
Position
23:48843474..48934858
AA seq 749 aa
MGRSESQMDITDISTPRPKKQRWTSLEISLSVLVLLLTIIAVTMIALYATYDDGICKSSD
CIKSAARLIQNMDATAEPCTDFFKYACGGWLKRNVIPETSSRYSNFDILRDELEVVLKDV
LQEPKTEDIVAVQKAKTLYRSCINESAIDSRGGQPLLSLLPDIYDWPVATDNWEQTYGTS
WTAEKSIAQLNSKYGKKVILNFFVGTDDKNSVNHIIHIDQPRLGLPSRDYYVCTGIYEEA
CTAYKDFMISVARLIRKEKGLLIDENQLSLEMNRVMELEKEIASATTKPEDRNDPMLLYN
KMTLAQIQNNFTLEIDGKPFSWSNFTNEIMSTVNINIPNEEEVVVYAPEYLTKLKLILTK
YSSRDLQNLMSWRFIMDLVSSLSRNYKESRNAFRKALYGTTSETATWRRCANYVNGNMEN
AVGRLYVEAAFAGESKHVVEDLITQIRAVFIQTLDDLTWMDAETKKKAEEKALAIKERIG
YPDDIISNDSKLDNEYLELNYREDEYFENIIQNLKFSQNKQLKKLREKVDKDEWISGAAV
VNAFYSSGRNQIVFPAGILQPPFFSAQQSNSLNYGGIGMVIGHEITHGFDDNGRNFNKDG
DLVDWWTQQSANNFKDQSQCMVYQYGNFSWDLAGGQHLNGINTLGENIADNGGIGQAYRA
YQNYVKKNGEEKLLPGLDLNHKQLFFLNFAQVWCGTYRPEYAVNSIKTDVHSPGNFRIIG
TLQNSPEFSEAFHCRKNSYMNPEKKCRVW
NT seq 2250 nt   +upstreamnt  +downstreamnt
atgggcagatcagaaagtcagatggatataactgatatcagcactccaaggccaaagaaa
caacgatggacctccctggagatcagtctctccgtccttgtcctgctccttaccatcatc
gccgtgacaatgatcgcactctatgcaacctatgatgatggtatttgcaagtcatcagac
tgcataaaatcagctgctcgactgatccagaacatggatgccactgctgagccctgtaca
gacttttttaaatacgcctgtggaggctggttgaaacgcaacgtcattcctgagactagc
tcccgttacagtaactttgacattttaagagatgaacttgaagtcgttttgaaagatgtt
cttcaggaacccaaaactgaggatatagtagcagtgcagaaagcaaaaacgttgtacaga
tcttgtataaatgaatctgctattgatagcagaggcggacaacctctgctcagtctgtta
ccagatatctatgactggccagtagcaacggataattgggagcaaacatatggtacttct
tggacagctgagaagtctattgcacaactgaattctaaatatgggaaaaaagtcattctt
aatttttttgttggcacggatgataagaactctgtgaaccatataattcatattgaccag
cctcgacttggcctcccgtccagagactactatgtctgcactggaatatatgaagaggct
tgcacagcgtataaagattttatgatttctgtggccagattgattcgtaaggagaaaggg
ctgctcatcgatgaaaaccagctttctttggaaatgaacagagttatggaattggaaaaa
gaaattgccagtgctacaactaaacctgaagatcgaaatgatcccatgcttctttataac
aaaatgacattagcccagatccaaaataactttacactagagattgatgggaagccattc
agctggtcaaatttcacaaatgaaatcatgtcaactgtgaatattaatattccaaatgag
gaagaagtggtcgtttatgctccagaatatttaaccaaacttaagctcattcttaccaaa
tattcctccagagatcttcaaaatttaatgtcctggcggttcataatggatcttgtaagc
agcctcagccgaaactacaaggagtcccgaaatgctttccgcaaggccctttatggcaca
acatcagaaacagcaacatggagacgttgtgcgaactatgtcaatgggaatatggaaaat
gctgtgggaaggctgtacgtggaagcagcatttgctggagagagtaaacatgtggttgag
gatttgattacacagatccgtgcagtttttattcagactttagatgacctcacttggatg
gatgctgaaacgaaaaagaaagctgaggaaaaggccttagcaattaaagaaagaattggc
tatcctgatgacatcatttcaaatgatagtaaactggataatgaatacctggagttgaac
tacagggaagatgaatactttgaaaacataattcaaaacttgaagttcagccaaaataaa
cagctcaagaagctccgagaaaaagtggacaaggatgagtggataagcggagcagctgta
gtcaatgcattttattcttcaggcagaaatcagatagtcttcccagctggcattctgcag
ccccccttcttcagtgcccagcagtctaactccttgaactacgggggtatcggcatggtc
ataggacacgaaatcacccatggcttcgatgacaatggcagaaattttaacaaggatgga
gacctcgttgactggtggactcaacagtcggcaaataattttaaagaccaatcccaatgc
atggtgtaccagtatggaaacttctcctgggacctagcaggtggacagcatctcaatggg
attaatacactgggagaaaatatcgctgataatggaggtattggccaagcatacagagcc
tatcaaaattatgttaaaaagaacggtgaagaaaaactacttcctggacttgacctaaat
cacaaacagctgttcttcctcaactttgcccaggtgtggtgtgggacctacaggccagag
tatgccgtcaactccattaaaacagatgttcacagtccagggaatttcaggattattggg
actttgcagaactcccctgagttttcagaggccttccattgccgcaagaattcatacatg
aatccagaaaagaaatgccgagtttggtga

  All links  
Ontology (5)   
   KEGG BRITE (5)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   RefGene (2)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (8)   
   UniProt (2)   
   RefSeq(pep) (6)   
DNA sequence (12)   
   RefSeq(nuc) (6)   
   GenBank (3)   
   EMBL (3)   
Protein domain (2)   
   Pfam (2)   
All databases (41)   

Download RDF
DBGET integrated database retrieval system