KEGG   Canis lupus familiaris (dog): 479191
Entry
479191            CDS       T01007                                 
Symbol
ACTN2
Name
(RefSeq) alpha-actinin-2
  KO
K21073  actinin alpha 2/3
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04820  Cytoskeleton in muscle cells
cfa05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    479191 (ACTN2)
 09160 Human Diseases
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    479191 (ACTN2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    479191 (ACTN2)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:cfa04812]
    479191 (ACTN2)
   04147 Exosome [BR:cfa04147]
    479191 (ACTN2)
Membrane trafficking [BR:cfa04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    479191 (ACTN2)
Cytoskeleton proteins [BR:cfa04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     479191 (ACTN2)
Exosome [BR:cfa04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   479191 (ACTN2)
  Exosomal proteins of colorectal cancer cells
   479191 (ACTN2)
  Exosomal proteins of bladder cancer cells
   479191 (ACTN2)
SSDB
Motif
Pfam: Spectrin CH EFhand_Ca_insen EF-hand_1 EF-hand_7 EF-hand_6 EF-hand_8 CAMSAP_CH AIF-1 Nsp1_C EF-hand_11 HisKA_2 XisI
Other DBs
NCBI-GeneID: 479191
NCBI-ProteinID: XP_856116
Ensembl: ENSCAFG00000010822
VGNC: 37549
UniProt: A0A8C0MXP0
Position
4:complement(3395551..3461987)
AA seq 894 aa
MNQIEPGVQYNYVYDDDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIE
NIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANVNKALDYIASKGVKLVSIGAE
EIVDGNVKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNIQNFHTSW
KDGLGLCALIHRHRPDLIDYSKLNKDDPIGNINLAMEIAEKHLDIPKMLDAEDIVNTPKP
DERAIMTYVSCFYHAFAGAEQAETAANRICKVLAVNQENERLMEEYERLASELLEWIRRT
IPWLENRTPEKTMQAMQKKLEDFRDYRRKHKPPKVQEKCQLEINFNTLQTKLRISNRPAF
MPSEGKMVSDIAGAWQRLEQAEKGYEEWLLNEIRRLERVEHLAEKFRQKASTHETWAYGK
EQILLQKDYESASLTEVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHDAVNVN
DRCQKICDQWDRLGTLTQKRREALERTEKLLETIDQLHLEFAKRAAPFNNWMEGAMEDLQ
DMFIVHSIEEIQSLITAHEQFKATLPEADGERQSIMAIQNEVEKVIQSYNIRISSSNPYS
TVTMDELRAKWDKVKQLVPIRDQSLQEELARQHANERLRRQFAAQANAIGPWIQNKMEEI
ARSSIQITGALEDQMNQLKQYEHNIINYKNNIDKLEGDHQLIQEALVFDNKHTNYTMEHI
RVGWEVLLTTIARTINEVETQILTRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRA
CLISMGYDLGEAEFARIMTLVDPNGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILAS
DKPYILAEELRRELPPDQAQYCIKRMPAYSGPGSVPGALDYTAFSSALYGESDL
NT seq 2685 nt   +upstreamnt  +downstreamnt
atgaaccagatagagcccggcgtgcagtacaactacgtgtacgacgatgacgagtacatg
atccaggaggaggagtgggaccgcgacctgctgctcgacccggcctgggagaagcaacag
aggaagaccttcactgcctggtgtaattcccacctaaggaaagctggcacccagattgag
aacatcgaggaagatttcaggaatggccttaagctcatgctgcttctggaagtcatctca
ggggaaaggctgcccaaacctgaccgaggaaaaatgcgattccacaaaattgctaatgtc
aacaaagccttggattacatagccagcaaaggtgtgaaactggtgtccatcggggctgaa
gaaattgtggatggcaatgtaaagatgacactgggtatgatctggaccattatccttcgc
tttgctattcaggatatctcagttgaagaaacctctgcgaaagaaggtctgttgctttgg
tgtcagaggaaaactgccccttacagaaatgtgaacatccagaacttccacaccagctgg
aaggatggccttggactctgtgcgctcatccacagacaccggcccgacctcattgactac
tcaaagcttaacaaggatgacccaataggaaatattaacctggccatggaaattgcagag
aagcacctggatattcccaaaatgctggatgctgaagacattgtgaacactcctaaaccc
gatgaaagagctatcatgacatacgtttcctgcttctaccatgcgtttgcgggcgcggag
caggccgagacagcagctaacaggatatgtaaggttcttgctgtgaatcaagagaatgag
aggctgatggaagaatatgagaggctagcgagtgagctgttggaatggattcgtcgtacg
atcccctggctggagaaccggacccccgagaagaccatgcaggccatgcagaagaagctg
gaggacttccgggattaccggcgcaagcacaagccgcccaaggtgcaggagaagtgccag
ctggagatcaacttcaacacactgcagaccaagctgcggatcagcaaccggcctgccttc
atgccctccgagggcaagatggtgtcggacattgctggtgcctggcagaggctggagcag
gccgagaagggctatgaggaatggctgctgaatgagattcggaggctggagcgtgtggaa
cacctggcggagaagtttaggcagaaggcttcgacgcatgaaacgtgggcttatggcaaa
gaacagatcttgctgcagaaggactatgagtcggcttctttgaccgaggtccgggccctg
ctgcggaaacacgaggccttcgagagtgacctggctgcacaccaggaccgggtggagcag
atagcggccatcgcgcaggagctcaatgaactggactatcacgatgctgtgaatgtcaac
gatcggtgccagaagatctgtgaccagtgggacagattgggaacgcttactcagaagagg
agagaggccctggagagaactgagaaattgctagaaaccatcgatcagctccacttggag
tttgccaagagagctgctcctttcaacaattggatggaaggtgccatggaggacctacaa
gacatgttcattgtccacagcattgaggaaatccagagtctgatcaccgcccacgagcag
ttcaaggcaacgctgccggaggctgatggtgaacggcagtccatcatggccattcagaac
gaggtggagaaggtgatccagagctacaacatcagaatcagctccagcaatccctatagt
actgtcaccatggatgagctccgggccaagtgggacaaggtgaagcagcttgtgcccatc
cgggatcagtccctgcaggaggagctggcccgccagcatgccaatgagcgtctgcggcgc
cagtttgctgcacaggccaatgccattgggccatggatccagaacaagatggaggagatt
gcccggagctccatccagatcacaggagccctggaggaccagatgaatcaactgaagcag
tatgaacacaacatcatcaactataagaacaacatcgacaagctagagggagaccatcag
ctcatccaagaggccctggtctttgacaacaagcacaccaattacaccatggagcacatc
cgtgttgggtgggaggtgctgctgacgaccatcgccagaaccatcaacgaagtagagacg
cagatcctgacgagagatgccaagggcattacccaggagcagatgaacgagtttagggcc
tccttcaaccactttgacaggaggaagaatggcctgatggatcacgaggacttcagagcc
tgcttgatttccatgggttatgatttgggcgaagctgaatttgcacgcatcatgacccta
gtggatcccaacggacagggcactgtcaccttccagtccttcatcgacttcatgacgagg
gagacagctgacacagacacggcagagcaggtcattgcctccttccggatcctggcttct
gataagccatacatcctggcagaggagctgcgtcgagagctgcccccagatcaggcccag
tactgcatcaagaggatgcccgcctactcaggcccgggcagtgtgcccggagccctggat
tacaccgcgttctcctctgccctgtacggggaaagcgatctgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (19)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (13)   
   Pfam (13)   
All databases (50)   

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