KEGG   Canis lupus familiaris (dog): 607482
Entry
607482            CDS       T01007                                 
Symbol
BCR
Name
(RefSeq) breakpoint cluster region protein isoform X1
  KO
K08878  breakpoint cluster region protein [EC:2.7.11.1]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa05200  Pathways in cancer
cfa05220  Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    607482 (BCR)
  09162 Cancer: specific types
   05220 Chronic myeloid leukemia
    607482 (BCR)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    607482 (BCR)
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:cfa04131]
    607482 (BCR)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     607482 (BCR)
Protein kinases [BR:cfa01001]
 Serine/threonine kinases: Other
  BCR family
   607482 (BCR)
Membrane trafficking [BR:cfa04131]
 Others
  Rho GTPase associated proteins
   Rho GTPase-activating proteins
    607482 (BCR)
SSDB
Motif
Pfam: RhoGAP Bcr-Abl_Oligo RhoGEF PH_19 C2 IQ_SEC7_PH PH PH_5
Other DBs
NCBI-GeneID: 607482
NCBI-ProteinID: XP_013963680
Ensembl: ENSCAFG00000013773
VGNC: 38420
Position
26:26931961..27056311
AA seq 1291 aa
MVDPVGFAEAWKAQFPDSEPPRMELRSVGDIEQELERCKASIRRLEQEVNQERFRMIYLQ
TLLAKEKKSYDRQRWGFRRAAQPPDGAAEPRAPAPRPPPAPAPPPAPAPAPPPADGADPP
AAEEPEPRPDGEGSPSKARPAAARRPADREERGAPTSVAALRSNFERIRKGHGPPGAADP
EKPFYVNVEFHHERGLVKVNDKDVSDRISSLGSQAMQMERKKSQLGAGPGPGPADAPRPS
YRGRPSESSCGLDGDYEDAELNPRFLKDNLINANGGGRPPWPPLEYQPYQSIYVGGMMME
GDAKGPLLRSQSTSEQEKRLTWPRRSYSPRSFEDSGGGYTPDCSSNENLTSSEEDFSSGQ
SSRVSPSPTTYRMFRDKSRSPSQNSQQSFDSSSPPTPQCHKRHRQGQVIVAEATIVGVRK
TGQIWPSDGDSLSGRLPQDGTFHGDPDASFGTPPGYGCAADRAEEQRRHQDGLPYIDDSP
SSSPHLGSKGRGSRDTLASGALESTKVSELDLEKGMEMRKWVLSGILASEETYLSHLEAL
LLPMKPLKAAATTSQPVLTSQQIETIFFKVPELYEIHKEFYDGLFPRVQQWSHQQRVGDL
FQKLASQLGVYRAFVDNYGVAMETAEKCCQANSQFAEISENLKARSNKDAKDQTTKNSLE
TLLYKPVDRVTRSTLVLHDLLKHTPSSHPDHPLLQDALRISQNFLSSINEEITPRRQSMT
VKKGEHRQLLKDSFMVELVEGARKLRHVFLFTDLLLCTKLKKQSGGKTQQYDCKWYIPLT
DLSFQTVDESEAAPNIPLVLDEELDAMKIKISQIKNDIQREKRANKGSKAIERLKKKLSE
QESLLLLMSPSMAFRVHSRNGKSYTFLISSDYERAEWRENIREQQKKCFKSFSLTSVELQ
MLTNSCVKLQTVHSIPLTINKEDDESPGLYGFLNVIVHSATGFKQSSNLYCTLEVDSFGY
FVNKAKTRVYRDTAEPNWNEEFEIELEGSQTLRILCYEKCYNKTKITKEDGESTDRIMGK
GQVQLDPQALQDRDWQRTVIAMNGIEVKLSVKFTSREFSLKRMPSRKQTGVFGVKIAVVT
KRERSKVPYIVRQCVEEIERRGMEEVGIYRVSGVATDIQALKAAFDVNNKDVSVMMSEMD
VNAIAGTLKLYFRELPEPLFTDEFYPNFAEGIALSDPVAKESCMLNLLLSLPEANLLTFL
FLLDHLKRVAEKETVNKMSLHNLATVFGPTLLRPSEKESKLPANPSQPISMTDSWSLEVM
SQVQVLLYFLQLEAIPAPDSKRQSILFSTEV
NT seq 3876 nt   +upstreamnt  +downstreamnt
atggtggaccccgtgggcttcgccgaggcgtggaaggcgcagttcccggactcggagccg
ccgcgcatggagctgcgctcggtgggcgacatcgagcaagagctggagcgctgcaaggcc
tccatccggcgcctggagcaggaggtgaaccaggagcgcttccgcatgatctacctgcag
acgctgctggccaaggagaagaagagctacgaccggcagcgctggggcttccgccgcgcc
gcgcagccccccgacggcgccgccgagccccgcgcgcccgcgccgcgcccgccgcccgcg
cccgcgcccccgcccgcgcccgcgcccgcgcccccgcccgccgacggcgccgacccgccg
gccgccgaggagcccgagccccggcccgacggagagggctccccgagcaaggcccggccc
gcggccgcccgcaggcccgcggaccgcgaggagcgcggcgcccccaccagcgtggccgcg
ctcaggtccaactttgagaggatccgcaagggccacggcccgcccggggcggccgacccc
gagaagcccttctacgtgaacgtcgagttccaccacgagcgcggcctggtgaaggtcaac
gacaaagacgtgtcggaccggatcagctccctgggcagccaggccatgcagatggagcgc
aagaagtcccagctcggcgccggccccgggcccggcccggccgacgcgcccaggccctcg
taccggggccgcccctccgagagcagctgcggcctcgacggcgactacgaggacgcggag
ctgaacccccgcttcctgaaggacaacctcatcaacgccaacggcggcggcaggccccct
tggccgcccctggagtaccagccctaccagagcatctacgtcgggggtatgatgatggaa
ggggacgccaagggcccgctcctgcgcagccagagcacctcggagcaggagaagcgcctc
acctggccccgcaggtcctactcccctcggagctttgaggacagcggaggcggctacacg
ccggactgcagctccaacgagaacctcacctccagcgaggaggacttctcctcgggccag
tctagccgcgtgtcccccagccctaccacctaccgcatgtttcgagacaaaagccgctcc
ccgtcgcagaactcccagcagtccttcgacagcagcagccccccgacgccgcagtgccat
aagcggcaccggcagggccaggtcatcgtggccgaggccaccatcgtgggcgtccgcaag
acggggcagatctggcccagcgacggggacagcttgtcgggcaggctgcctcaggatggc
accttccatggagacccagatgcgtcgtttggaacgccacctgggtatggctgtgctgcg
gaccgggctgaggagcagcgccggcaccaggacgggctgccctacatcgatgactcgccc
tcctcctcaccccaccttggcagcaaaggcaggggcagccgggacacactggcctcagga
gccctggagtccaccaaagtgagtgagttggacttggaaaaaggcatggagatgaggaaa
tgggtcctgtctggaatcctggctagcgaagagacttacctgagccacctggaggcactg
ctgctgcccatgaaacctttgaaggctgctgccaccacctctcagccggtgctgacaagc
cagcagatcgagaccatcttcttcaaagtgcctgagctctatgagatccacaaggagttc
tatgatgggctcttcccccgagtacagcagtggagtcaccagcagcgagtgggtgatctc
ttccagaagctggccagccagctgggtgtgtaccgagcctttgtagacaactatggcgtc
gccatggaaacggcggagaagtgctgtcaggccaactctcagtttgcagaaatctctgag
aacctgaaagccagaagcaacaaggatgccaaggaccagacgaccaagaactctttggaa
accctgctctacaagcctgtggaccgggtgacacgcagcacgctggtcctgcatgactta
ctgaagcacacaccatccagccaccctgaccaccctctgctgcaggatgccctccgtatc
tcacagaacttcctgtccagtatcaatgaggaaatcacaccccgccggcaatccatgacc
gtgaagaagggagagcaccggcagctgctgaaggacagtttcatggtggagctggtggag
ggggcccgcaagctgcgccacgtcttcctgttcactgacctgctcctctgtaccaagctc
aagaagcagagtggaggcaaaacccagcagtatgactgcaagtggtacatccccctcacg
gatctcagcttccagacggtggatgagtcagaggcggctcccaacatccccctggtgctg
gacgaggagctggatgccatgaagatcaagatatcccagatcaagaatgatatccagaga
gagaagagggcaaacaagggcagcaaggccatcgagcggctgaagaagaagctgtcggag
caggagtcgctgctcctgctcatgtcccccagcatggccttcagagtacacagccgcaat
ggcaagagttacacgttcctcatctcatctgactatgagcgtgctgagtggagggagaac
atccgagagcagcagaagaagtgtttcaaaagcttctccctaacatctgtggagctgcag
atgctgaccaattcgtgtgtcaaacttcagaccgtccacagcattccactgaccatcaac
aaagaagatgatgaatctccagggctgtacgggttcttgaatgtcatcgtccattccgcc
accggctttaagcagagttcaaatctgtactgcaccctggaggtggactcctttggttat
tttgtgaataaagccaagacacgtgtttacagagacacagctgagcccaactggaacgag
gaatttgagatcgagctagaaggctcccagaccttgaggatactgtgctatgaaaaatgt
tacaacaaaacgaagatcaccaaagaagatggcgaaagcacagacaggatcatggggaag
ggccaggtccagctggacccccaggccctgcaggacagagactggcagcggactgtcatc
gccatgaatgggatcgaagtgaagctctcagtcaagttcaccagcagggagttcagcttg
aagagaatgccttcccgaaaacagaccggcgtcttcggagtcaagattgccgtggtcacc
aagagggagagatccaaggtgccctacatcgtgcgccagtgcgtggaggagattgagcgc
cgaggcatggaggaagtgggcatctaccgcgtgtctggagtggccacggacatccaggct
ctgaaggcagcctttgacgtcaataacaaggacgtgtcggtgatgatgagcgagatggac
gtgaacgccattgccggcacgctgaagctgtacttccgcgaactaccagagcctctcttc
accgacgagttctaccccaacttcgccgagggcatcgctctgtcagaccctgtcgcaaag
gagagctgcatgcttaatttactgctgtcactcccagaggccaacctgctgaccttcctc
ttccttctggaccacctgaaaagggtggcagaaaaggagacagtgaacaagatgtccctg
cacaaccttgccacagtcttcggccccacactgctccggccatcagagaaggagagcaag
ctccctgccaaccccagccagcccatatccatgaccgacagctggtccctggaagtcatg
tcccaggtccaggtgctgctgtacttcctgcagctggaggccatccctgccccagacagc
aagagacagagcatcctattctccactgaagtctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (24)   
   KEGG ORTHOLOGY (1)   
   RefGene (18)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (5)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (8)   
   Pfam (8)   
All databases (50)   

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