KEGG   Canis lupus familiaris (dog): 608021
Entry
608021            CDS       T01007                                 
Symbol
SQLE
Name
(RefSeq) squalene monooxygenase
  KO
K00511  squalene monooxygenase [EC:1.14.14.17]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00100  Steroid biosynthesis
cfa01100  Metabolic pathways
Module
cfa_M00101  Cholesterol biosynthesis, FPP => cholesterol
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    608021 (SQLE)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.17  squalene monooxygenase
     608021 (SQLE)
SSDB
Motif
Pfam: SE FAD_binding_3 DAO NAD_binding_8 Pyr_redox FAD_binding_2 Pyr_redox_2 TrkA_N Shikimate_DH ApbA 3HCDH_N NAD_Gly3P_dh_N Sacchrp_dh_NADP AlaDh_PNT_C Thi4 F420_oxidored NAD_binding_2
Other DBs
NCBI-GeneID: 608021
NCBI-ProteinID: XP_005627990
Ensembl: ENSCAFG00000001056
VGNC: 46786
UniProt: A0A8C0MWQ3 A0A8I3NFI4
Position
13:22958181..22982327
AA seq 573 aa
MWTFLGIATFTYFYKKCGDFVSFANKELLLCVLVFLSLGLVLSYRCRYRSGALLGRQRSG
SQFALFSDILSALPFIGFFWAKSPPGSEDKEQPASRRHKKGTSISETTLIGAAASSIPSQ
NDPEVIIVGSGVLGSALAAVLSRDGRKVTVIERDLKEPDRIVGEFLQPGGYRVLEDLGLK
DAVEDIDAQVVDGYIIHDQDSKSEVQIPYPVSENSQVRSGRAFHHGRFIMGLRKAAMAEP
NTKFIEGIVLQLLEEDDAVMGVQYRDKETGDVKELHAPLTVVADGLFSKFRKNLISNKVS
VSSHFVGFLMKNAPQFKANHAELILTNPSPVLIYQISSNETRVLVDIRGEMPRNLREYMA
EKIYPQLPDHLKEPFLEAIQNSRLRSMPASFLPSSPVNKRGVLLLGDAYNMRHPLTGGGM
TVVFKDLKLWRKLLKSIPDLYDDAAVFQAKKSFYWERKTSHSFVVNILAQALYELFSAKD
DSLHQLRKACFLYFKLGGECVAGPVGLLSVLSPNPLILIGHFFAVALYATYFCFKSEPWI
TKPRAIFSSGAVLYKACSVIFPLIYSEIKYLVN
NT seq 1722 nt   +upstreamnt  +downstreamnt
atgtggaccttcttgggcattgccactttcacgtacttttacaagaaatgcggagacttc
gtgtctttcgccaacaaggagctgctgctgtgcgtgctggtgttcctgtccctgggcctg
gtgctctcctaccgctgccgctaccggagcggggccctcctggggcgccagcggagcggc
tcccagttcgcgctcttctcagatattctgtcggccttgcctttcattggcttcttctgg
gccaagtcacccccgggatcagaggataaagagcagcctgcgtctaggaggcacaaaaaa
ggaaccagtatttcagaaacaaccttaataggagcagctgcctcttcaataccttctcaa
aatgacccagaagttatcattgtgggatctggtgtacttggctctgctttggcagccgtg
ctttccagagatggaagaaaagtgacagtgattgagagagatttaaaggagcccgaccgg
atagttggagaatttctgcagccaggtggttaccgtgtccttgaagacctgggtcttaaa
gatgcagtggaagatattgatgcccaggtggtagatggctacataatccatgatcaggat
agcaaatcagaggttcagattccttaccctgtgtcagaaaacagtcaggtgcggagtgga
agagctttccatcatggaagattcatcatgggtctccggaaagcagctatggcagagccc
aatacaaagttcattgaaggcatcgtgctacaattattggaagaagatgatgctgtgatg
ggagttcaatacagggataaagaaaccggggacgtcaaggaactccatgctccattgact
gttgttgcagatggacttttttccaagttcaggaaaaacctgatctccaataaagtttcg
gtttcgtctcattttgttggctttctcatgaagaatgcaccacagtttaaggcaaatcat
gctgaacttattttgactaatccgagtccagttctcatctatcagatttcatctaatgaa
actcgagtacttgttgacatccgaggagaaatgcccaggaacttaagagaatacatggct
gaaaaaatttacccacaattacctgatcacctcaaagaaccgttcctggaagccattcag
aattctcgtttgagatctatgccagcaagttttcttccttcttcaccagtgaacaaacga
ggtgttcttcttttgggagatgcttataatatgaggcatcctcttaccggaggaggaatg
actgttgtttttaaagatctaaaactatggagaaaattgctaaagagtatccctgacctt
tatgacgatgcagctgttttccaggccaaaaaatcattctattgggagaggaaaacatct
cattcctttgttgtgaatatccttgctcaggctctttatgaattattttctgccaaggat
gattccctacatcaactaagaaaagcctgttttctttatttcaaacttggtggcgaatgt
gttgctggtcctgttgggctgctttctgtcctgtctcctaaccctctcattttaatcgga
cacttctttgctgtggccctctatgccacatatttctgctttaaatcggaaccttggatt
acaaaaccccgagccattttcagtagtggtgctgtattgtacaaagcatgttctgtaatc
tttcctctgatttactcggaaattaagtacctggtcaattaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (2)   
   KEGG MODULE (2)   
Chemical substance (6)   
   KEGG COMPOUND (6)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (12)   
   UniProt (2)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (17)   
   Pfam (17)   
All databases (63)   

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