KEGG   Canis lupus familiaris (dog): 612941
Entry
612941            CDS       T01007                                 
Symbol
CAMK2A
Name
(RefSeq) calcium/calmodulin-dependent protein kinase type II subunit alpha isoform X1
  KO
K04515  calcium/calmodulin-dependent protein kinase (CaM kinase) II [EC:2.7.11.17]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04012  ErbB signaling pathway
cfa04020  Calcium signaling pathway
cfa04024  cAMP signaling pathway
cfa04066  HIF-1 signaling pathway
cfa04114  Oocyte meiosis
cfa04148  Efferocytosis
cfa04217  Necroptosis
cfa04261  Adrenergic signaling in cardiomyocytes
cfa04310  Wnt signaling pathway
cfa04360  Axon guidance
cfa04713  Circadian entrainment
cfa04720  Long-term potentiation
cfa04722  Neurotrophin signaling pathway
cfa04725  Cholinergic synapse
cfa04728  Dopaminergic synapse
cfa04740  Olfactory transduction
cfa04750  Inflammatory mediator regulation of TRP channels
cfa04911  Insulin secretion
cfa04912  GnRH signaling pathway
cfa04916  Melanogenesis
cfa04921  Oxytocin signaling pathway
cfa04922  Glucagon signaling pathway
cfa04925  Aldosterone synthesis and secretion
cfa04934  Cushing syndrome
cfa04971  Gastric acid secretion
cfa05012  Parkinson disease
cfa05022  Pathways of neurodegeneration - multiple diseases
cfa05031  Amphetamine addiction
cfa05152  Tuberculosis
cfa05200  Pathways in cancer
cfa05205  Proteoglycans in cancer
cfa05214  Glioma
cfa05415  Diabetic cardiomyopathy
cfa05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    612941 (CAMK2A)
   04310 Wnt signaling pathway
    612941 (CAMK2A)
   04066 HIF-1 signaling pathway
    612941 (CAMK2A)
   04020 Calcium signaling pathway
    612941 (CAMK2A)
   04024 cAMP signaling pathway
    612941 (CAMK2A)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    612941 (CAMK2A)
  09143 Cell growth and death
   04114 Oocyte meiosis
    612941 (CAMK2A)
   04217 Necroptosis
    612941 (CAMK2A)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    612941 (CAMK2A)
   04922 Glucagon signaling pathway
    612941 (CAMK2A)
   04912 GnRH signaling pathway
    612941 (CAMK2A)
   04921 Oxytocin signaling pathway
    612941 (CAMK2A)
   04916 Melanogenesis
    612941 (CAMK2A)
   04925 Aldosterone synthesis and secretion
    612941 (CAMK2A)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    612941 (CAMK2A)
  09154 Digestive system
   04971 Gastric acid secretion
    612941 (CAMK2A)
  09156 Nervous system
   04725 Cholinergic synapse
    612941 (CAMK2A)
   04728 Dopaminergic synapse
    612941 (CAMK2A)
   04720 Long-term potentiation
    612941 (CAMK2A)
   04722 Neurotrophin signaling pathway
    612941 (CAMK2A)
  09157 Sensory system
   04740 Olfactory transduction
    612941 (CAMK2A)
   04750 Inflammatory mediator regulation of TRP channels
    612941 (CAMK2A)
  09158 Development and regeneration
   04360 Axon guidance
    612941 (CAMK2A)
  09159 Environmental adaptation
   04713 Circadian entrainment
    612941 (CAMK2A)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    612941 (CAMK2A)
   05205 Proteoglycans in cancer
    612941 (CAMK2A)
  09162 Cancer: specific types
   05214 Glioma
    612941 (CAMK2A)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    612941 (CAMK2A)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    612941 (CAMK2A)
   05022 Pathways of neurodegeneration - multiple diseases
    612941 (CAMK2A)
  09165 Substance dependence
   05031 Amphetamine addiction
    612941 (CAMK2A)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    612941 (CAMK2A)
   05415 Diabetic cardiomyopathy
    612941 (CAMK2A)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    612941 (CAMK2A)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:cfa01001]
    612941 (CAMK2A)
Enzymes [BR:cfa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.17  Ca2+/calmodulin-dependent protein kinase
     612941 (CAMK2A)
Protein kinases [BR:cfa01001]
 Serine/threonine kinases: CAMK group
  CAMK2 family
   612941 (CAMK2A)
SSDB
Motif
Pfam: Pkinase CaMKII_AD PK_Tyr_Ser-Thr DUF4440 SnoaL_3 SnoaL_2 APH Kdo SnoaL_4
Other DBs
NCBI-GeneID: 612941
NCBI-ProteinID: XP_005619356
Ensembl: ENSCAFG00000018163
VGNC: 38680
UniProt: A0A8C0S5Z7 A0A8I3MXQ9
Position
4:58567052..58631982
AA seq 489 aa
MATITCTRFTEEYQLFEELGKGAFSVVRRCVKVLAGQEYAAKIINTKKLSARDHQKLERE
ARICRLLKHPNIVRLHDSISEEGHHYLIFDLVTGGELFEDIVAREYYSEADASHCIQQIL
EAVLHCHQMGVVHRDLKPENLLLASKLKGAAVKLADFGLAIEVEGEQQAWFGFAGTPGYL
SPEVLRKDPYGKPVDLWACGVILYILLVGYPPFWDEDQHRLYQQIKAGAYDFPSPEWDTV
TPEAKDLINKMLTINPSKRITAAEALKHPWISHRSTVASCMHRQETVDCLKKFNARRKLK
GAILTTMLATRNFSGGKSGGNKKNDGVKKRKSSSSVQLMESSESTNTTIEDEDTKVRKQE
IIKVTEQLIEAISNGDFESYTKMCDPGMTAFEPEALGNLVEGLDFHRFYFENLWSRNSKP
VHTTILNPHIHLMGDESACIAYIRITQYLDAGGIPRTAQSEETRVWHRRDGKWQIVHFHR
SGAPSVLPH
NT seq 1470 nt   +upstreamnt  +downstreamnt
atggccaccatcacctgcacccgcttcacagaagagtatcagctcttcgaggaactggga
aagggagccttctcagtggtacgcaggtgtgtgaaggtgctggctggccaggagtatgct
gctaagatcatcaacaccaaaaagctctcagccagagaccatcagaagctggagcgcgaa
gctcgcatctgccgcctgctgaaacaccccaacatagtccggcttcacgacagcatctct
gaggagggacatcattacctgatcttcgacctggttactggcggggagctgtttgaggac
atcgtggcccgggagtattacagtgaggctgatgccagccactgtatccagcagatcctg
gaggccgtgttgcactgccatcagatgggtgtggtgcaccgggacctgaagccggagaat
ctgttgttggcctccaaactcaagggcgcagcggtgaagctggcggactttggcctggcc
atagaggtagaaggggagcagcaggcatggttcgggttcgcagggacgccgggatacctc
tccccagaagtgctgcggaaggacccatatgggaaacccgtggatctgtgggcctgtggg
gtcatcctctacattctgctggttgggtatcccccattctgggatgaagaccagcaccgc
ctgtaccagcagatcaaagctggcgcctatgatttcccatcaccagaatgggacaccgtc
accccggaagccaaggatctgatcaataagatgctgaccatcaacccatccaaacgcatc
acggccgctgaggccctcaagcacccctggatctcgcaccggtccaccgtggcctcctgc
atgcacagacaggagaccgtggactgcctgaagaagttcaacgccaggagaaaactgaag
ggagccatcctcaccactatgctggctaccaggaacttctctggagggaagagtggagga
aacaaaaagaatgatggtgtgaagaaaagaaagtccagttccagcgttcagttaatggaa
tcttcagagagtaccaacaccaccattgaggatgaagacaccaaagtgcggaaacaggag
attataaaagtgacagagcagctgattgaagccataagcaatggagattttgagtcctac
acgaagatgtgtgaccccgggatgacagccttcgaacctgaggccctggggaacctggtc
gagggcctggacttccatcgattctattttgaaaacctgtggtctcggaacagcaagcct
gtgcacaccaccatcctgaacccccatatccatctgatgggcgacgagtcggcctgcatc
gcctacatccgcatcacgcagtacctggatgcgggtggcatcccccgcacggcccagtca
gaggagacccgcgtctggcaccgccgggacggcaaatggcagattgtccacttccacaga
tctggggcaccctccgtcctgccccattga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (34)   
   KEGG PATHWAY (34)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (9)   
   KEGG ORTHOLOGY (1)   
   RefGene (3)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (12)   
   UniProt (2)   
   RefSeq(pep) (10)   
DNA sequence (10)   
   RefSeq(nuc) (10)   
Protein domain (9)   
   Pfam (9)   
All databases (79)   

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