KEGG   Canis lupus familiaris (dog): 474536
Entry
474536            CDS       T01007                                 
Symbol
TXNRD1
Name
(RefSeq) thioredoxin reductase 1, cytoplasmic
  KO
K22182  thioredoxin reductase (NADPH) [EC:1.8.1.9]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa00450  Selenocompound metabolism
cfa05200  Pathways in cancer
cfa05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    474536 (TXNRD1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    474536 (TXNRD1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    474536 (TXNRD1)
Enzymes [BR:cfa01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.9  thioredoxin-disulfide reductase
     474536 (TXNRD1)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox Pyr_redox_3 Glutaredoxin FAD_binding_2 AlaDh_PNT_C Thi4 FAD_oxidored HI0933_like NAD_binding_8 DAO GIDA
Other DBs
NCBI-GeneID: 474536
NCBI-ProteinID: NP_001116145
Ensembl: ENSCAFG00000001944
VGNC: 48021
Position
10:complement(33824269..33941521)
AA seq 655 aa
MGCGKSKVRAGAPPQPEANGRRGPGSQSSAKDHFPCQPLPENPAIGVSRPSGSTSTSLLD
PRARLRAYIDSHPVVIVSKSACKRCAEVKKLFESMSVPYFLLELDQAEDARGLELALSEL
TPETDAPVVFVKRRNIGGHGPTLKAYQEGRLQNLLNMNGSEDLPEVYDYDLIIIGGGSGG
LAAAKEAARYNKKIMVLDFVTPTPRGTRWGLGGTCVNVGCIPKKLMHQAALLGQALQDSR
NYGWSTEETVKHDWDKMTEAVQNHIGSLNWGYRVALREKKVTYENAYGQFVGPHRIKATN
NKGKEKIYSAERFLIATGERPRYLGIPGDREYCISSDDLFSLPYCPGKTLVVGASYVALE
CAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGVKFIRQFVPIKVEQIEAGTP
GRLRVVAQSTSSSETIEGEYNTVLLAIGRDACTRKIGLETVGVKINEKTGKIPVTDEEQT
NVPYIYAIGDILEGKLELTPVAIQAGRLLAQRLYAGSNVKCDYENVPTTVFTPLEYGACG
LSEERAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKVICNIKDNERVVGFHVLGPN
AGEVTQGFAAALKCGLTKMQLDSTIGIHPICAEVFTTLSVTKRSGASILQAGCUG
NT seq 1968 nt   +upstreamnt  +downstreamnt
atgggctgcgggaagagcaaggtgagggcgggcgccccgccccagccggaagccaacggc
cgccggggcccgggcagccaatcgtcagctaaggaccatttcccttgtcagcctttgcca
gaaaacccagccattggtgtgagcagaccctcagggtccaccagcacaagcctcttggac
cccagagcccggctcagggcctatatagatagccaccctgtagtcattgtcagcaagtcc
gcatgcaagcgctgtgctgaggtaaagaagttatttgagtcgatgagtgttccgtatttt
ttgctcgaacttgatcaagcagaggacgcccggggcctggaactagcgctctcggagctg
acgccggagaccgacgcgcccgtggtgttcgtgaagcggcggaacataggcggccatggt
ccaaccctgaaggcttatcaagagggcagacttcaaaacctactaaacatgaatggctct
gaggatcttcctgaggtctatgactatgacctcatcatcattggagggggctcaggagga
ctggcagctgctaaggaggcagccagatataataagaagataatggtcctggattttgtc
actccaacccctcgtggaactagatggggtctcggaggaacatgtgtaaatgtgggttgc
atacctaaaaaactgatgcaccaagcagctctgttaggacaagccctacaggactctcgg
aactatggttggagcaccgaggagacggttaaacatgactgggataaaatgacagaagct
gtacagaaccacattggctctctgaactggggctaccgggtagctctgcgggagaaaaag
gtgacctatgagaatgcatatggacagtttgtgggtcctcataggattaaggcaacaaat
aacaaaggcaaagaaaaaatttattcagcagagagatttctcattgctactggtgagagg
ccacgttacttgggaatccccggtgaccgagagtactgcatcagcagtgatgatcttttt
tccttaccttattgcccgggtaagaccctggtggttggagcatcctatgttgccctggaa
tgtgctggatttcttgctggcattggtttagatgttactgttatggtacgatccattctc
cttagaggatttgaccaggacatggccaacaaaattggtgaacatatggaagaacatggt
gtcaagtttataagacagtttgtaccaataaaagttgaacaaattgaagcagggacacca
ggccgactcagggtggtagctcagtccaccagtagtagtgaaaccattgaaggagagtat
aatacggtattgctggcaataggaagagatgcttgcacaagaaaaattggcttagaaacc
gtgggagtaaaaataaatgaaaagactggaaaaatacctgtcacagatgaagagcagacc
aatgtaccttacatctatgccattggtgatatattggaggggaagctggagctcacccca
gtagcaatccaggcaggaagattgttggctcagaggctttatgctggctccaatgtgaag
tgtgattatgaaaatgttccaacaactgtgtttactcctttggaatatggtgcctgtggt
ctttctgaggagagagctgtggagaaattcggggaagaaaatattgaggtttatcatagt
tacttctggccattggagtggacaattccctcaagagataataacaaatgttacgcaaaa
gtaatctgtaacatcaaagataatgaacgtgtcgtgggcttccacgtactgggtccaaat
gctggagaagttacacaaggctttgcagctgccctcaagtgtggactgaccaaaatgcag
ctggacagtaccattggaatccaccccatctgtgcagaggtattcacgaccttgtcagtg
accaagcgctctggggcaagcatcctccaggctggctgctgaggttaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (8)   
   KEGG COMPOUND (8)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (11)   
   KEGG ORTHOLOGY (1)   
   RefGene (5)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (13)   
   Pfam (13)   
All databases (43)   

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