KEGG   Cupriavidus gilardii: CR3_2065
Entry
CR3_2065          CDS       T04050                                 
Symbol
leuC
Name
(GenBank) 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit
  KO
K01703  3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:4.2.1.33 4.2.1.35]
Organism
cgd  Cupriavidus gilardii
Pathway
cgd00290  Valine, leucine and isoleucine biosynthesis
cgd00660  C5-Branched dibasic acid metabolism
cgd01100  Metabolic pathways
cgd01110  Biosynthesis of secondary metabolites
cgd01210  2-Oxocarboxylic acid metabolism
cgd01230  Biosynthesis of amino acids
Module
cgd_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:cgd00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00660 C5-Branched dibasic acid metabolism
    CR3_2065 (leuC)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CR3_2065 (leuC)
Enzymes [BR:cgd01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.33  3-isopropylmalate dehydratase
     CR3_2065 (leuC)
    4.2.1.35  (R)-2-methylmalate dehydratase
     CR3_2065 (leuC)
SSDB
Motif
Pfam: Aconitase Aconitase_C
Other DBs
NCBI-ProteinID: ALD91276
UniProt: A0A0M4KXV8
Position
1:complement(2527705..2529717)
AA seq 670 aa
MDRLQIDGRILFLADCPRTIERQLRGEALTLEQVGGLRDDVSTDEITPVPILTHFDDQLG
RYPYTGFRAGGAQPIGADAIRQGGFAVTVAGNRYGKGSSREHSPAAEKLAGIRLVIARSF
ERIYRQNADNIGLLTSTDFGLIPRLQAGEAIPLEELLAGRDALAAQILREGGLLRFGQRH
LRGLAGDGAPAVRPTQPTQPAADRPRTLFEKIVARHAIATEVTPAEPAPGDGIFVRADWR
FIHEYYTGMAAHMLHAALGRPLALHAPERVVVFEDHTSYVEQSPAHLRGGLVRNVVQMRD
AQRRFVADYALRFHRTLTEDEALRDDGSNVAGISHAMMAEHYALPGQLVVGTDSHTPHSG
ALGCVAFGVGTTDMANAFVTGAVRMTLPASLRIVLDGALPAGVTAKDVVLHLLALPAIRG
GTGVGKVFEFTGPVVSALSTDERATLTNMCAELGGFTGIVAPDAETVRFLKDRRGIDFTV
EPWMHSDDGADYAATIHVDCSGLAPMVARPGDPGNGLALSGLTEPVRIDIAYGGSCTAGK
REDFDHYHAVLRWAAERGLRVPAGVTLYLQFGTTAVRDYCIAQGYLEAFDAVGATILQPS
CGACANCGPGSSTAAEQVTVSSINRNFPGRSGPGQVWLASPPTVAASAIAGRLLSFDDLR
AQFGEPRRTA
NT seq 2013 nt   +upstreamnt  +downstreamnt
atggaccgcctgcagatcgatggccgcattctgtttcttgccgattgcccgcggaccatc
gaacggcagttgcgcggcgaggcgctgacgctggagcaggtcggcgggctgcgcgacgat
gtctcgaccgacgagatcaccccggtaccgatcctgacccatttcgacgaccagctcggg
cgctatccctataccggctttcgcgcgggcggcgcccagccgatcggcgccgatgcgatc
cggcagggcggctttgccgtgaccgtcgccggcaaccgctacggcaagggctcgtcgcgc
gagcacagcccggcggccgagaaactggccggcatccggctggtgattgcccgcagcttc
gagcggatctaccggcagaacgccgacaatatcggcctgctgacatcgaccgacttcggc
ctgattccccggctgcaggctggcgaggcgattcccctcgaggaactgctggccggccgc
gatgcactggcggcgcagatcctgcgcgagggcggcctgctgcgcttcggccagcggcat
ctgcggggcctcgccggagacggcgcgccagcggtgcggcccacgcagccaacgcagccg
gccgcggatcggccgcgcacgctgttcgagaagatcgtcgcccgccatgcgatcgcgacc
gaagtcacgccggccgaacccgctccgggcgacggcatcttcgtgcgagccgactggcgc
ttcatccacgagtactacaccggcatggcggcccatatgctgcatgccgcgctgggccgg
ccgctggcattgcacgcgcccgagcgcgtcgtcgtgttcgaggaccacacctcgtatgtc
gagcaaagcccggcccatctgcgcggcggcctggtgcggaacgtcgtgcagatgcgcgac
gcccagcggcgtttcgtcgcggactacgcgctgcggttccaccggacgttgaccgaggac
gaggcgctgcgcgacgacggcagcaatgtcgccggcatctcgcacgcgatgatggccgag
cattacgcgctgccggggcagctggtggtcggtaccgactcgcacacgccgcacagcggc
gcgctcggctgcgtggcgttcggcgtcggcacgaccgacatggccaacgccttcgtgacc
ggcgcggtgcgcatgacgttgcccgcgtcgttgcggatcgtgctggacggtgcgttgccg
gccggcgtgacggccaaggacgtggtgctgcatctgctggccttgccggcgatccgtggc
ggcacgggcgttggcaaggtattcgagttcaccggtccggtggtgtcggcgctgtcgacc
gacgaacgcgcgacgctgaccaatatgtgcgccgagctcggcggcttcaccggcatcgtc
gcgcccgatgcggagacggtgcgcttcctgaaggaccggcgcggcatcgatttcacggtc
gagccgtggatgcatagcgacgacggcgccgactatgccgcgacgatccacgtcgattgc
agcggcctggcgccgatggtggcgcggccgggcgatcccggcaacggcctggcgctgtcc
ggtctgaccgagccggtacggatcgacatcgcctacggcggctcgtgcacggccggcaag
cgcgaggacttcgaccactatcatgcggtgctgcgctgggccgccgagcgcgggctgcgg
gtgccggccggcgtcacgctgtatctgcagttcggcacgacggcggtgcgcgactactgc
atcgcccagggctatctggaggcgttcgacgcggtcggcgcgacgatcctgcagccttcc
tgcggcgcctgcgcgaactgcgggccgggttcgtcgacggcggccgagcaggtcacggtc
agctcgatcaatcgcaatttccccggccgttcggggccggggcaggtgtggctggccagt
ccgccgacggtggcggccagcgcgattgcggggcggctgctgtcgttcgatgatttgcgg
gcgcagttcggcgagccgcggcgcacggcgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (8)   
   KEGG PATHWAY (6)   
   KEGG MODULE (2)   
Chemical substance (19)   
   KEGG COMPOUND (19)   
Chemical reaction (13)   
   KEGG ENZYME (2)   
   KEGG REACTION (11)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (2)   
   Pfam (2)   
All databases (49)   

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