KEGG   Carboxydothermus hydrogenoformans: CHY_0521
Entry
CHY_0521          CDS       T00287                                 
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
chy  Carboxydothermus hydrogenoformans
Pathway
chy00290  Valine, leucine and isoleucine biosynthesis
chy00620  Pyruvate metabolism
chy01100  Metabolic pathways
chy01110  Biosynthesis of secondary metabolites
chy01210  2-Oxocarboxylic acid metabolism
chy01230  Biosynthesis of amino acids
Module
chy_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:chy00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    CHY_0521 (leuA)
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    CHY_0521 (leuA)
Enzymes [BR:chy01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     CHY_0521 (leuA)
SSDB
Motif
Pfam: HMGL-like LeuA_dimer Lipoprotein_2 EFhand_Ca_insen
Other DBs
NCBI-ProteinID: ABB15265
UniProt: Q3AEQ5
Position
452918..454447
AA seq 509 aa
MERVRIFDTTLRDGEQSPGVSLNAMEKLQIARQLQKLGVDVIEAGFPITSPGDKEAVSLI
AREVKGVVVAALARASALDIETAWDAIKDAESPRIHTFIATSDIHLKYKLKMDRETVVER
AVAAVKLAKKFTADVEFSAEDASRSDLDFLCRVVEAAVKAGATTINIPDTVGYAEPEEFG
EFICKILEKVPVMDRAVLSVHCHDDLGLAVANSLAAIKNGARQVECTINGIGERAGNCSL
EEIVMALYTRKDVLPFYTGIKTEEIYRTSKLVSNLTGMPVQPNKAIVGKNAFSHESGIHQ
DGVLKERTTYEIMNPRLVGIPESRLVLGKHSGRHALKERLLELGYELTEEQLNEAFVKFK
ALADKKKEVTDQDLEAMMEEEIRKVPETYTLDYFHISTGSTIIPTATVGLIKEGEKLEDA
ATGDGPVDAIYKAINKITGLTPVLEQYSINAVTSGEDALGEVVVKLKNGLGKIVTGRGVS
TDILEASAKAYLNGINKLLFDYQAKGEKQ
NT seq 1530 nt   +upstreamnt  +downstreamnt
atggaaagggttaggatttttgatacgacgttaagggatggggaacagtcgccaggagtt
agtttaaatgctatggagaaattgcaaatcgcccggcagttacaaaagctgggcgttgat
gttatagaggcaggttttcctataacttctcccggagataaggaagccgtttccttaatt
gcccgggaagtaaaaggggtggtagtggctgccctggcccgggcttcggctttggatata
gaaacggcctgggacgccattaaagatgcggaaagtccccggattcatacttttattgcc
acttccgatattcatttgaaatataagctgaaaatggaccgggaaacggtagtggaacgg
gcggtagcagcggtcaaacttgctaaaaaatttaccgccgatgtggagttttcggcggaa
gatgcttcaagaagtgacctggactttttgtgccgggtggtggaagcggcggtaaaagcg
ggagctactaccataaacattcccgataccgttggctatgccgaaccggaagagtttggg
gagtttatttgcaaaattttagaaaaagttccggtaatggaccgggcggtgttaagcgtt
cactgtcatgatgatttgggccttgcggtggccaatagtttagctgccatcaaaaacggc
gcccggcaggtggaatgtaccattaacggaattggtgaacgggctggaaactgttcctta
gaggagattgtaatggctctttatacccgcaaagatgtattgcctttttataccggcatt
aaaaccgaggagatttaccggaccagtaagctcgttagcaatttaaccgggatgccggta
cagcccaacaaagcgattgtagggaaaaatgccttttcccacgaatcggggattcaccag
gatggggttttaaaggaaagaactacttatgaaataatgaatcccaggctggtgggtatt
cccgaatcccgtctggtactgggtaaacattcgggaagacatgcgttaaaggagaggtta
ttagagcttggttatgaattaaccgaagagcagttgaatgaggcttttgttaaatttaaa
gctttagccgataagaaaaaagaagttaccgatcaggatttagaagcaatgatggaagaa
gaaataagaaaagttcccgaaacttacaccctggattatttccatatttctaccggttca
acgattattcccacggccacggtgggcttaatcaaggaaggggaaaaattagaagacgcc
gccaccggcgatggaccggtggatgccatttataaagctatcaataaaataaccggttta
actccggttttagagcaatattcaattaatgccgtaacttctggcgaagatgccctggga
gaagtagtggtaaaactaaaaaatggcctcgggaaaattgtcaccggtcgcggagtttcc
accgatattttagaagcatcggccaaggcttatttaaatggtatcaataaattacttttt
gattaccaggcgaaaggggagaagcagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (9)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   SWISS-PROT (1)   
Protein domain (4)   
   Pfam (4)   
All databases (35)   

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