KEGG   Cupriavidus necator N-1: CNE_1c14040
Entry
CNE_1c14040       CDS       T01564                                 
Symbol
pdhL
Name
(GenBank) dihydrolipoamide dehydrogenase PdhL
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
cnc  Cupriavidus necator N-1
Pathway
cnc00010  Glycolysis / Gluconeogenesis
cnc00020  Citrate cycle (TCA cycle)
cnc00260  Glycine, serine and threonine metabolism
cnc00280  Valine, leucine and isoleucine degradation
cnc00310  Lysine degradation
cnc00380  Tryptophan metabolism
cnc00620  Pyruvate metabolism
cnc00630  Glyoxylate and dicarboxylate metabolism
cnc00640  Propanoate metabolism
cnc00785  Lipoic acid metabolism
cnc01100  Metabolic pathways
cnc01110  Biosynthesis of secondary metabolites
cnc01120  Microbial metabolism in diverse environments
cnc01200  Carbon metabolism
cnc01210  2-Oxocarboxylic acid metabolism
cnc01240  Biosynthesis of cofactors
Module
cnc_M00009  Citrate cycle (TCA cycle, Krebs cycle)
cnc_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
cnc_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
cnc_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
cnc_M00621  Glycine cleavage system
Brite
KEGG Orthology (KO) [BR:cnc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    CNE_1c14040 (pdhL)
   00020 Citrate cycle (TCA cycle)
    CNE_1c14040 (pdhL)
   00620 Pyruvate metabolism
    CNE_1c14040 (pdhL)
   00630 Glyoxylate and dicarboxylate metabolism
    CNE_1c14040 (pdhL)
   00640 Propanoate metabolism
    CNE_1c14040 (pdhL)
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    CNE_1c14040 (pdhL)
   00280 Valine, leucine and isoleucine degradation
    CNE_1c14040 (pdhL)
   00310 Lysine degradation
    CNE_1c14040 (pdhL)
   00380 Tryptophan metabolism
    CNE_1c14040 (pdhL)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    CNE_1c14040 (pdhL)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cnc04147]
    CNE_1c14040 (pdhL)
Enzymes [BR:cnc01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     CNE_1c14040 (pdhL)
Exosome [BR:cnc04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   CNE_1c14040 (pdhL)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Biotin_lipoyl Pyr_redox FAD_oxidored GIDA Pyr_redox_3 AlaDh_PNT_C DEC-1_N Biotin_lipoyl_2 GCV_H NAD_binding_8 FAD_binding_2 PYNP_C HI0933_like FAD_binding_3
Other DBs
NCBI-ProteinID: AEI76751
UniProt: G0ESV4
Position
1:1414831..1416615
AA seq 594 aa
MSVIEVKVPDIGDFDAVEVIEVLVKAGDTVEVEQSLIVLESDKASMDVPSSAAGKVVEVK
VKVGDKVGQGAVICTIEAQQAAAAPAPAQAPAPAQAPAPAAAAPAPAPAAASHSGGADIQ
CEMLVLGAGPGGYSAAFRAADLGMNTVLVERYGTLGGVCLNVGCIPSKALLHNAAVIDEA
KALAAHGILFGEAKIDLDGLRHYKNQVVGKLTGGLAGMAKARKVQVVRGVGNFLDPHHLE
VELTEGEGKQTTGKKTVIRFEKAIIAAGSQAVKLPFIPEDPRIVDSTGALELPEVPNKML
VIGGGIIGLEMATVYSTLGADIDVVEMLDGLMNGADRDLVKVWEKKNKDRFGKVMLKTKT
VGVEAKSDGIYVKFEGEAAPAEPQRYDLVLVSVGRSPNGKRISAEKAGVAVTDRGFINVD
NQLRTNVPHIFAIGDIVGQPMLAHKAVHEAHVAAEAAHGEKAYFDAKQIPSVAFTDPEVA
WAGLTEDECKANGIKYSKGVFPWAASGRAIANGRDEGFTKLIFDEETHRVIGGGIVGTHA
GDLISEVCLAIEMGADAVDIGKTIHPHPTLGESIGMAAEIYEGTCTDVPPPRKR
NT seq 1785 nt   +upstreamnt  +downstreamnt
atgagtgtgatcgaagtcaaggtgccggatatcggcgatttcgacgcggtggaagtgatc
gaggtgctggtcaaggccggcgacacggtcgaagtggaacagtccctgatcgtgctggaa
tccgacaaggccagcatggacgtgccgtcgtcggccgccggcaaggtggttgaggtcaag
gtcaaggtcggcgacaaggtcggccagggcgcggtgatctgcaccatcgaggcccagcag
gccgcggccgccccggcgcccgcgcaagccccggcaccggcgcaggctcccgcacccgcg
gcggctgctccggccccggctcctgccgccgccagccacagcggcggcgccgatatccag
tgcgagatgctggtgctgggcgccggccccggcggctattcggccgctttccgcgccgca
gacctgggcatgaacaccgtgctggtggagcgctacggcaccctgggcggcgtctgcctg
aatgtgggctgcatcccgtccaaggcgctgctgcacaacgccgccgtgatcgacgaagcc
aaggcgctggctgcgcacggcatcctgttcggcgaagccaagatcgacctggacggcctg
cgccactacaagaaccaggtggtcggcaagctgaccggcggcctggccggcatggccaag
gcgcgcaaggtgcaggtggtgcgcggcgtcggcaatttcctcgacccgcatcacctggag
gtggagctgactgaaggcgagggcaagcagaccaccggcaagaagaccgtgatccgtttc
gagaaggccatcatcgccgccggcagccaggcggtgaagctgcccttcatccccgaagac
ccgcgcatcgtcgactcgaccggcgcgctggagctgcccgaagtgcccaacaagatgctg
gtcattggcggcggcatcatcggcctggaaatggccacggtgtacagcacgctgggtgcc
gacatcgacgtcgtggaaatgctcgacggcctgatgaacggcgctgaccgcgacctggtc
aaggtctgggaaaagaaaaacaaggaccgcttcggcaaggtcatgctgaagaccaagacc
gtcggcgtggaagccaaatcggacggcatctacgtcaagttcgaaggcgaggccgcaccg
gccgagccgcagcgctacgacctggtgctggtgtcggtaggccgctcgcccaacggcaag
cgcatcagcgccgagaaggcaggcgttgccgtgaccgaccgcggctttatcaacgtcgac
aatcagttgcgcaccaacgtgccgcatatctttgcgatcggcgatatcgtcggccagccg
atgctggcgcacaaggccgtgcacgaagcccacgtggcggcggaagccgcccatggcgag
aaggcctacttcgatgccaagcagatcccgtcggtggccttcaccgatccggaagtggcc
tgggccggcctgaccgaagacgaatgcaaggcgaatgggatcaagtacagcaagggcgtg
ttcccctgggcggcttcgggccgcgccatcgccaacggccgcgacgagggcttcaccaag
ctgatcttcgacgaggaaacccatcgcgtgatcggcggcggcatcgtcggcacgcatgcc
ggcgacctgatcagcgaggtctgcctggcgatcgagatgggcgccgacgcggtggatatc
ggcaagaccatccatccgcacccgacgctgggtgagtcgatcggcatggcggcggagatc
tatgaaggtacgtgtactgacgtgccgccgccgcgcaagcgctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (23)   
   KEGG PATHWAY (16)   
   KEGG MODULE (7)   
Chemical substance (27)   
   KEGG COMPOUND (27)   
Chemical reaction (11)   
   KEGG ENZYME (1)   
   KEGG REACTION (10)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (16)   
   Pfam (16)   
All databases (85)   

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