KEGG   Cupriavidus necator N-1: CNE_BB1p00420
Entry
CNE_BB1p00420     CDS       T01564                                 
Symbol
iolA
Name
(GenBank) methylmalonate semialdehyde dehydrogenase
  KO
K00140  malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:1.2.1.18 1.2.1.27]
Organism
cnc  Cupriavidus necator N-1
Pathway
cnc00280  Valine, leucine and isoleucine degradation
cnc00410  beta-Alanine metabolism
cnc00562  Inositol phosphate metabolism
cnc00640  Propanoate metabolism
cnc01100  Metabolic pathways
cnc01200  Carbon metabolism
Brite
KEGG Orthology (KO) [BR:cnc00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    CNE_BB1p00420 (iolA)
   00562 Inositol phosphate metabolism
    CNE_BB1p00420 (iolA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    CNE_BB1p00420 (iolA)
  09106 Metabolism of other amino acids
   00410 beta-Alanine metabolism
    CNE_BB1p00420 (iolA)
Enzymes [BR:cnc01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.18  malonate-semialdehyde dehydrogenase (acetylating)
     CNE_BB1p00420 (iolA)
    1.2.1.27  methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
     CNE_BB1p00420 (iolA)
SSDB
Motif
Pfam: Aldedh LuxC DUF826
Other DBs
NCBI-ProteinID: AEI81475
UniProt: F8GV48
Position
BB1p:complement(40215..41729)
AA seq 504 aa
MTAPYTSPSEVIHYVSGEPYEGNGKRAQAVFNPATGAVARQVRLGTVEDVDAAVASAVAA
FPKWADTPPIRRARVMLKFLELMNQHKDELAAIITAEHGKVLSDAAGEVSRGIDIIEFAC
GVPQLLKGDFTDQVSTGMDNWTLRQPLGVVAGITPFNFPCMVPCWMFPVAIATGNCFILK
PSERDPSASLFMARLLKEAGLPDGVFNVIQGDKTVVDALLHHRDVKAVSFVGSTPIANYI
YETGARLGKRVQALGGAKNHMVVMPDADIDQALDGLIGAAYGSAGERCMAISVAVLVGDV
ADKIMPKLEARARELVIKNGMEADAEMGPVVTGQALERIENYIALGVEEGAKLVVDGRNY
KVPGHEQGFFTGGTLFDNVTPEMRIYKEEIFGPVLSCVRVDDFAQAVKLINEHEFGNGVA
CYTRDGQVAREFCRRIEVGMVGINVPIPVPMAWHGFGGWKRSLFGDMHAYGEEGVRFYTR
QKSIMQRWPNDTARGAEFAMPTAK
NT seq 1515 nt   +upstreamnt  +downstreamnt
atgactgcgccctacaccagcccctccgaggtaattcattacgtttccggcgagccgtat
gaaggcaatggcaagcgcgcgcaggcggtgttcaatcccgccaccggcgccgtagcacgc
caagttcgcctgggcaccgtcgaggatgtggacgccgcggtggcctcggcagtagctgca
tttcccaagtgggcggacacgcctcccattcgccgggcgcgggtgatgctgaagttcctg
gaactgatgaaccaacacaaggacgagcttgcagcgatcatcacggccgagcacggcaag
gtgctgagcgatgcagcaggcgaagtcagccgtggcatcgacatcatcgaatttgcctgc
ggcgtacctcaactgctcaagggcgacttcacggaccaggtgtcgaccggcatggacaac
tggacgctgcgccagcctctcggcgttgtcgcgggaatcacgccgttcaacttcccctgc
atggtgccgtgctggatgttccctgttgcgatcgccaccggcaactgcttcattctgaag
ccgagtgagcgcgatccttcggcatcgctcttcatggcccgcctccttaaggaagccgga
cttccggatggcgtgttcaacgtcattcagggcgacaagaccgttgtcgacgcactgctc
catcaccgtgacgtcaaggccgtgagcttcgtggggtccacgccgattgcaaactacatc
tacgagaccggggcgagactcggcaagcgtgttcaggcactgggcggtgcgaagaaccac
atggtggtgatgccagatgcagacatagaccaggccttggatggattgatcggcgccgcc
tatggctccgctggcgaacgctgcatggccatctccgtggcagtgctcgtgggcgacgtt
gccgacaagatcatgcctaagctcgaagccagagcacgcgaactggtcatcaagaacggc
atggaggccgacgcggaaatgggcccggtcgtcacgggccaggcgctcgaacgcatcgag
aactacattgccctaggggtggaagaaggggcaaagcttgtcgtcgatggccgaaactac
aaggtgcccggacacgaacaagggttctttactggcggcacgctgttcgacaacgtaacg
cccgaaatgcgcatctacaaggaagagatcttcggccccgtgctgtcgtgtgtgcgagtg
gatgacttcgcacaagccgtgaagctcatcaacgaacacgagttcggtaatggcgtcgcg
tgctatacgcgtgatgggcaagtggcccgcgaattttgccgccgcatcgaagtgggaatg
gtcggcatcaacgtgcccatccctgtgccgatggcatggcacggctttggtggctggaag
cgctcgttgttcggcgacatgcacgcctacggcgaagaaggcgtgcggttctacacccgg
cagaagagcatcatgcaacggtggccgaacgacaccgcgcgtggcgcagagttcgcaatg
cccactgcaaagtaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (2)   
   KEGG REACTION (4)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (35)   

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