KEGG   Cryptococcus neoformans var. neoformans JEC21: CNG00590
Entry
CNG00590          CDS       T00243                                 
Name
(RefSeq) folic acid and derivative metabolism-related protein, putative
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
cne  Cryptococcus neoformans var. neoformans JEC21
Pathway
cne00670  One carbon pool by folate
cne01100  Metabolic pathways
cne01240  Biosynthesis of cofactors
Module
cne_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:cne00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    CNG00590
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cne04147]
    CNG00590
Enzymes [BR:cne01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     CNG00590
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     CNG00590
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     CNG00590
Exosome [BR:cne04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   CNG00590
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH CbiA OCD_Mu_crystall
Other DBs
NCBI-GeneID: 3258947
NCBI-ProteinID: XP_571769
UniProt: Q5KEG6
Position
7:join(156478..156731,156807..159089,159138..159666)
AA seq 1021 aa
MRISRPLGQLNLYARTSPRISFPLPSARVISAPLRQSLPPPRLRVNTPLASRSFSISSTH
LAKMSADVEMTSQSAKIIDGTAIAKQIRTSISQAITDLHASNPTFHQPHLVIFQLGSSAA
SSTYIRMKLKAAEESGMTVEHIKIPSDEESGALKGTGVKRVLEAVKKANQDEKVSGILVQ
LPLEGAGKAEEKAVVDSVDVTKDVDGFHPENIGLLSSRISEPFFTPCTPAGAIKLIESTG
FNLAGSNVVVLGRSDIVGTPVCALLRKKDATVTQCHSRTKNVERIISQADVIVAAIGQAE
FVRGEWLKPGAIVIDVGTNYIPDASKKSGQRLVGDVHFESASKVASYITPVPGGVGPMTV
AMLMNNTFEAAKRQWSSRRAKQLIPLPLEIKEKVPSDIEIAVAQTPKPVAEIAEEIGVHP
DEVESYGRYKAKIELSVLDRLKERKDGKYIVVAGITPTPLGEGKSTTTIGLAQALGAHLH
KTAIACVRQPSQGPTFGIKGGAAGGGYSQVIPMTEFNLHLTGDIHAITAANNLLAAAIDA
RMFHEATQTDKGLFNRLCPPKKGVRTFSKPMIARLHKLGINKTNPSDLTEEEAARFARLD
IDPATLTWNRVLDTNDRYLRQITVGQAPTEKGLERKTAFDIAVASECMAVLALSKDLADM
RARLGRMVVASSKAGEPITAEDIGCAGAMAVLMKDAIKPTIMQTLEGTPVFVHAGPFANI
AHGNSSIIADRIALKLAGVEEGDDESRNGYVITEAGFGADIGMEKFCNIKTRVSGLKPSA
VVLVATIRALKMHGGGPAVTPGKPLDQVYVEENLELLEKGCANLGKHIENAKKFGLKVVV
AINKFSNDTAAEMALVQEYALKVGADYAVPADHWARGGAGAVDLANAVIEACATPSTFDF
LYDLNQPLTKKIEIIAKEMYGADGISLSAEAQAEIDRYEKQGYGGLPICMAKTALSLSDD
PSKKGVPTGFTLPIRNVRLSAGASFVYPLVGDMSTMPGLTTRPGFYDIDLNPDTGEIEGL
F
NT seq 3066 nt   +upstreamnt  +downstreamnt
atgcgaatctcacggcccctcggtcaactcaatctttacgctaggacaagtccgagaatt
tctttcccccttccttcggcccgtgtgatttccgcgcctctgagacaatctctcccacca
cctcgccttcgtgtcaacactcctcttgccagccgctctttttccatttcctcaacacat
ctcgcaaaaatgtctgccgacgtcgaaatgacctctcagtccgcaaagatcattgacggc
actgccatcgcaaagcaaatccgtacctccatctcccaagccatcaccgacctccatgcg
tccaaccctaccttccatcagcctcatctcgtcatctttcagctcggctctagcgctgct
tcctctacttacattcgcatgaagctcaaggccgccgaagagtctggtatgactgtcgag
cacatcaagattccctctgacgaagagtctggtgcgctcaagggaactggtgtcaagcga
gtccttgaggcggtgaagaaagccaaccaggacgaaaaggtctctggtatcctcgtccag
ctccctcttgaaggtgccggtaaggctgaggagaaggctgttgttgacagcgtggatgtc
accaaggacgttgacggtttccacccggaaaacattggtctcctcagcagccgaatcagc
gagcccttcttcaccccttgcaccccagcgggtgctatcaagctcatcgagtccaccggt
ttcaacctcgctggttccaacgtcgtcgttctcggccgaagcgacattgtcggcacccct
gtctgcgctttgctccgaaagaaggacgcgaccgtcacccaatgccactctcgtaccaag
aacgttgagcgaatcatcagccaagctgatgtcattgtcgctgctatcggccaagccgag
tttgtacgtggcgagtggttgaagcctggcgcgattgtgattgatgtcggcaccaactac
attcccgacgcttccaaaaaatccggtcagcgccttgtcggtgatgttcactttgagtct
gccagcaaggtcgcctcttacattacccctgttcccggaggtgttggacccatgaccgtt
gcaatgctcatgaacaacactttcgaagctgccaagcgtcaatggtcttctcgccgagcc
aagcaactcatccctcttcctcttgagattaaagaaaaggtgccttctgatatcgagatc
gccgtcgcccagacccccaagcccgttgctgagattgccgaggagatcggtgtgcaccct
gacgaagttgagagctacggcagatacaaggccaagattgagctttccgttcttgacagg
ctcaaggagaggaaggatggcaagtacattgttgtcgccggtatcactcctaccccgctc
ggtgaaggcaagtctaccaccaccatcggtctcgcccaagctctcggtgcccatctccac
aagactgctatcgcctgtgtccgacaaccttcccagggacctactttcggtatcaagggt
ggtgccgccggtggtggttactcccaggttatccccatgaccgagtttaaccttcatttg
actggagatattcacgccatcacggctgccaacaatttgcttgctgctgctatcgacgcc
cgcatgttccacgaagctactcaaaccgacaagggtctcttcaaccgtctctgcccccct
aagaagggtgttcgcactttctccaagcctatgattgcccgtctccacaagctcggtatt
aacaagaccaacccgtctgatttgacagaagaagaggctgcccgattcgctcgtcttgat
atcgaccctgcgaccctcacttggaaccgagtgctcgacaccaacgatcgatacctccgt
caaattaccgtcggccaagctcccacagagaagggtctcgagcgaaagacggcgtttgac
attgccgtcgcttccgagtgtatggccgtgcttgctctcagtaaggatctcgccgatatg
cgagctcgtctcggtaggatggtcgtcgcgtcaagcaaggccggtgagcccatcactgcc
gaagacattggctgtgccggtgccatggctgttctcatgaaggacgctatcaaacctacc
atcatgcaaacccttgaaggtactcccgtctttgtccacgctggtccattcgccaatatt
gcccacggcaactcctccatcatcgcggaccgtatcgccctcaagctcgctggtgttgaa
gaaggcgacgatgagtcgaggaacggttacgtcattaccgaagctggtttcggcgctgat
attggtatggaaaagttctgcaacatcaagactcgagtctctggcttgaagcccagcgcg
gtggtgcttgtcgctacgatccgagctttgaaaatgcacggtggtggacctgccgttacc
cctggaaagcctcttgaccaggtctatgtggaggagaacttggagttgttggagaagggt
tgtgccaacttgggcaaacacattgagaatgccaagaagtttggtctgaaggttgttgtt
gctatcaacaagttttctaacgacaccgccgctgagatggcccttgtccaagaatacgct
ctcaaggttggagccgactacgccgtgcctgcagaccactgggctcgaggtggtgctggt
gccgttgacctcgccaacgccgtcatcgaagcctgcgccactccttccactttcgacttc
ctctatgacctcaaccaacccctcacaaagaagatcgagatcatcgccaaggagatgtac
ggtgccgacggtatctcactctccgctgaggctcaagccgagatcgacaggtacgagaag
caaggttacggtggtttgcctatttgcatggccaagaccgccttgtcactctctgacgat
cccagcaagaagggtgttcccaccgggttcactttgcctattaggaatgtgaggttgagt
gcaggcgcgagctttgtatacccccttgtgggtgatatgagcaccatgccaggtttgact
accaggcccggattctatgacattgatttgaaccccgacactggtgagattgagggcttg
ttctag

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (31)   
   KEGG ORTHOLOGY (1)   
   RefGene (27)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (65)   

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