KEGG   COMPOUND: C01946Help
Entry
C01946                      Compound                               

Name
Oleandomycin;
Amimycin;
Landomycin;
Matromycin;
Romicil
Formula
C35H61NO12
Exact mass
687.4194
Mol weight
687.8583
Structure
Mol fileKCF fileDB searchJmolKegDraw
Sequence
0 Mak  1 Mtk  2 Mtn  3 Mte  4 Mtk  5 Mtk  6 Mtn
  Gene
0-2 oleA1 [UP:Q9KIV4]; 3-4 oleA2 [UP:Q9KIV3]; 5-6 oleA3
[UP:Q07017]
  Organism
Streptomyces antibioticus
  Type
PK
Remark
ATC code: 
Drug group: 
Reaction
Pathway
Biosynthesis of 12-, 14- and 16-membered macrolides
Type I polyketide structures
Biosynthesis of antibiotics
ABC transporters
Module
M00775  
Oleandomycin biosynthesis, malonyl-CoA + methylmalonyl-CoA => 8,8a-deoxyoleandolide => oleandomycin
Enzyme
Brite
Compounds with biological roles [BR:br08001]
 Antibiotics
  Polyketides and nonribosomal peptides
   Macrolides
    C01946  Oleandomycin
Lipids [BR:br08002]
 PK  Polyketides
  PK04 Macrolides and lactone polyketides
   C01946  Oleandomycin
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01F MACROLIDES, LINCOSAMIDES AND STREPTOGRAMINS
    J01FA Macrolides
     J01FA05 Oleandomycin
      C01946  Oleandomycin
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   50S subunit inhibitor
    Macrolides
     Oleandomycin
      C01946  Oleandomycin
BRITE hierarchy
Other DBs
CAS: 
3922-90-5
PubChem: 
ChEBI: 
LIPIDMAPS: 
3DMET: 
NIKKAJI: 
KCF data Show

ATOM        48
            1   C1z C    23.5055  -12.4797
            2   C1x C    23.4937  -11.0541
            3   O2x O    24.7191  -11.7728
            4   C1x C    23.5055  -13.8816
            5   C5x C    22.2921  -11.7728
            6   C1y C    24.7249  -14.5709
            7   C1y C    21.0845  -12.4797
            8   O5x O    22.2921  -10.3826
            9   C1y C    24.7249  -15.9729
            10  C1a C    25.9267  -13.8757
            11  C1y C    21.0845  -13.8816
            12  C1a C    19.8709  -11.7728
            13  C1y C    23.5055  -16.6738
            14  O2a O    25.9207  -16.6738
            15  C1y C    19.8709  -14.5709
            16  O1a O    22.2921  -14.5709
            17  C1y C    23.5055  -18.0700
            18  C1a C    22.6421  -15.6229
            19  C1y C    27.3287  -16.6444
            20  C1y C    19.8709  -15.9729
            21  C1a C    18.6634  -13.8757
            22  O2a O    24.7249  -18.7651
            23  C1y C    22.2921  -18.7651
            24  C1y C    28.0060  -15.4250
            25  O2x O    28.0474  -17.8402
            26  O7x O    21.0845  -16.6738
            27  C1a C    18.6575  -16.6798
            28  C1y C    25.9325  -19.4602
            29  C7x C    21.0845  -18.0700
            30  C1a C    22.2921  -20.1611
            31  C1y C    29.4022  -15.4014
            32  O1a O    27.2755  -14.2174
            33  C1y C    29.4374  -17.8166
            34  C1x C    25.9325  -20.8680
            35  O2x O    27.1401  -18.7651
            36  O6a O    19.8709  -18.7651
            37  C1x C    30.1149  -16.5973
            38  N1c N    30.0796  -14.1820
            39  C1a C    30.8394  -18.2584
            40  C1y C    27.1401  -21.5573
            41  C1y C    28.3477  -19.4602
            42  C1a C    29.3491  -12.9862
            43  C1a C    31.4698  -14.2285
            44  C1y C    28.3477  -20.8680
            45  O2a O    27.1461  -22.9534
            46  C1a C    29.5553  -18.7651
            47  O1a O    29.5553  -21.5573
            48  C1a C    25.9385  -23.6543
BOND        51
            1     1   2 1
            2     1   3 1 #Up
            3     1   4 1
            4     1   5 1
            5     4   6 1
            6     5   7 1
            7     5   8 2
            8     6   9 1
            9     6  10 1 #Down
            10    7  11 1
            11    7  12 1 #Up
            12    9  13 1
            13    9  14 1 #Down
            14   11  15 1
            15   11  16 1 #Up
            16   13  17 1
            17   13  18 1 #Down
            18   19  14 1 #Up
            19   15  20 1
            20   15  21 1 #Down
            21   17  22 1 #Down
            22   17  23 1
            23   19  24 1
            24   19  25 1
            25   20  26 1
            26   20  27 1 #Down
            27   28  22 1 #Down
            28   23  29 1
            29   23  30 1 #Up
            30   24  31 1
            31   24  32 1 #Down
            32   25  33 1
            33   28  34 1
            34   28  35 1
            35   29  36 2
            36   31  37 1
            37   31  38 1 #Up
            38   33  39 1 #Up
            39   34  40 1
            40   35  41 1
            41   38  42 1
            42   38  43 1
            43   40  44 1
            44   40  45 1 #Up
            45   41  46 1 #Up
            46   44  47 1 #Down
            47   45  48 1
            48    2   3 1
            49   26  29 1
            50   33  37 1
            51   41  44 1

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