KEGG   COMPOUND: C05349Help
Entry
C05349                      Compound                               

Name
Ciprofloxacin
Formula
C17H18FN3O3
Exact mass
331.1332
Mol weight
331.3415
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
Same as: 
Pathway
ABC transporters
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01M QUINOLONE ANTIBACTERIALS
    J01MA Fluoroquinolones
     J01MA02 Ciprofloxacin
      D00186  Ciprofloxacin (JP17/USP/INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AE Fluoroquinolones
     S01AE03 Ciprofloxacin
      D00186  Ciprofloxacin (JP17/USP/INN)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA15 Ciprofloxacin
      D00186  Ciprofloxacin (JP17/USP/INN)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA07 Ciprofloxacin
      D00186  Ciprofloxacin (JP17/USP/INN)
USP drug classification [BR:br08302]
 Antibacterials
  Quinolones
   Ciprofloxacin
    D00186  Ciprofloxacin (JP17/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   624  Synthetic antibacterials
    6241  Pyridonecarboxylic acids
     D00186  Ciprofloxacin (JP17/USP/INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Ciprofloxacin
      D00186  Ciprofloxacin (JAN/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 CYP inhbitors
  CYP1A2
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
  CYP3A4
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
  CYP3A5
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
  CYP3A7
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
  CYP3A
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
 CYP substrates
  CYP1A2
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
  CYP3A4
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
 Transporter substrates
  OAT1
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
  OAT3
   Ciprofloxacin
    D00186  Ciprofloxacin (JAN/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00186  Ciprofloxacin
Antibacterials [br08350.html]
 D00186
BRITE hierarchy
Other DBs
CAS: 
85721-33-1
PubChem: 
ChEBI: 
PDB-CCD: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8y C    23.1552  -17.6571
            2   C8y C    23.1552  -19.0610
            3   C8x C    24.3486  -19.7630
            4   C8y C    25.6121  -19.0610
            5   C8y C    25.6121  -17.6571
            6   C8x C    24.3486  -16.9551
            7   N4y N    26.8054  -19.7630
            8   C8x C    27.9988  -19.0610
            9   C8y C    27.9988  -17.6571
            10  C8y C    26.8054  -16.9551
            11  N1y N    21.9619  -19.7630
            12  C1x C    20.7685  -19.0610
            13  C1x C    19.5050  -19.7630
            14  N1x N    19.5050  -21.1669
            15  C1x C    20.6983  -21.8689
            16  C1x C    21.9619  -21.1669
            17  X   F    21.9619  -16.9551
            18  O5x O    26.8054  -15.5512
            19  C6a C    29.1921  -16.9551
            20  O6a O    30.3855  -17.6571
            21  O6a O    29.1921  -15.5512
            22  C1y C    26.8054  -21.1669
            23  C1x C    27.5074  -22.3603
            24  C1x C    26.1035  -22.3603
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12    2  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   11  16 1
            19    1  17 1
            20   10  18 2
            21    9  19 1
            22   19  20 1
            23   19  21 2
            24    7  22 1
            25   22  23 1
            26   22  24 1
            27   23  24 1

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