KEGG   COMPOUND: C05981Help
Entry
C05981                      Compound                               

Name
Phosphatidylinositol-3,4,5-trisphosphate;
1-Phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate;
1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate)
Formula
C11H20O22P4R2
Structure
Mol fileKCF fileDB searchJmolKegDraw
Comment
Generic compound in reaction hierarchy
Reaction
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
Ras signaling pathway
Chemokine signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
Endocytosis
mTOR signaling pathway
PI3K-Akt signaling pathway
AMPK signaling pathway
VEGF signaling pathway
Focal adhesion
Tight junction
Platelet activation
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Fc gamma R-mediated phagocytosis
Neurotrophin signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Prolactin signaling pathway
Thyroid hormone signaling pathway
Aldosterone-regulated sodium reabsorption
Carbohydrate digestion and absorption
Chagas disease (American trypanosomiasis)
Toxoplasmosis
Hepatitis C
Measles
Influenza A
HTLV-I infection
Epstein-Barr virus infection
Pathways in cancer
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Melanoma
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Choline metabolism in cancer
Enzyme
2.7.1.153       3.1.3.67        3.1.3.86
Brite
Lipids [BR:br08002]
 GP  Glycerophospholipids
  GP09 Glycerophosphoinositol trisphosphates
   GP0901 Diacylglycerophosphoinositol trisphosphates
    C05981  1,2-Diacyl-sn-glycero-3-phospho-(1'-myo-inositol-3',4',5'-bisphosphate)
BRITE hierarchy
Other DBs
PubChem: 
ChEBI: 
KCF data Show

ATOM        39
            1   O1c O    26.0886  -23.8676
            2   P1b P    27.4862  -23.8618
            3   O1c O    28.8802  -23.8618
            4   O2b O    27.4862  -22.4667
            5   O1c O    27.4862  -25.2570
            6   P1b P    30.1416  -16.8696
            7   O2b O    30.1359  -18.2607
            8   O1c O    28.7492  -16.8753
            9   O1c O    30.1359  -15.4700
            10  O1c O    31.5410  -16.8696
            11  C1y C    28.7058  -18.9618
            12  C1y C    28.7058  -20.3645
            13  C1y C    27.4862  -18.2756
            14  C1y C    27.4862  -21.0754
            15  O2b O    29.9137  -21.0637
            16  C1y C    26.2911  -18.9618
            17  O1a O    27.4862  -16.8843
            18  C1y C    26.2911  -20.3645
            19  P1b P    31.3073  -21.0580
            20  O2b O    25.0747  -18.2614
            21  O1a O    25.0832  -21.0580
            22  O1c O    32.6985  -21.0580
            23  O1c O    31.3073  -19.6667
            24  O1c O    31.3073  -22.4574
            25  P1b P    23.6836  -18.2497
            26  O2b O    22.2840  -18.2497
            27  O1c O    23.6893  -16.8503
            28  O1c O    23.6777  -19.6410
            29  C1b C    22.2840  -16.8535
            30  C1c C    21.0768  -16.1592
            31  C1b C    21.0768  -14.7702
            32  O7a O    19.8754  -16.8535
            33  O7a O    22.2840  -14.0703
            34  C7a C    18.6668  -16.1521
            35  C7a C    22.2840  -12.6751
            36  O6a O    18.6668  -14.7631
            37  R   R    17.4655  -16.8464
            38  O6a O    21.0698  -11.9869
            39  R   R    23.4994  -11.9798
BOND        39
            1    11  13 1
            2    12  14 1
            3    12  15 1 #Down
            4    13  16 1
            5    13  17 1 #Down
            6    14  18 1
            7    14   4 1 #Up
            8    15  19 1
            9    16  20 1 #Up
            10   18  21 1 #Up
            11   19  22 1
            12   19  23 1
            13   19  24 2
            14   20  25 1
            15   25  26 1
            16   25  27 1
            17   25  28 2
            18   16  18 1
            19    2   4 1
            20    2   5 2
            21    1   2 1
            22    2   3 1
            23    6   7 1
            24    6   8 2
            25    6   9 1
            26    6  10 1
            27   11   7 1 #Up
            28   11  12 1
            29   26  29 1
            30   29  30 1
            31   30  31 1
            32   30  32 1 #Down
            33   31  33 1
            34   32  34 1
            35   33  35 1
            36   34  36 2
            37   34  37 1
            38   35  38 2
            39   35  39 1

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