KEGG   Chlorocebus sabaeus (green monkey): 103217637
Entry
103217637         CDS       T04361                                 
Symbol
CASP8
Name
(RefSeq) caspase 8
  KO
K04398  caspase 8 [EC:3.4.22.61]
Organism
csab  Chlorocebus sabaeus (green monkey)
Pathway
csab01524  Platinum drug resistance
csab04115  p53 signaling pathway
csab04210  Apoptosis
csab04215  Apoptosis - multiple species
csab04217  Necroptosis
csab04620  Toll-like receptor signaling pathway
csab04621  NOD-like receptor signaling pathway
csab04622  RIG-I-like receptor signaling pathway
csab04623  Cytosolic DNA-sensing pathway
csab04625  C-type lectin receptor signaling pathway
csab04657  IL-17 signaling pathway
csab04668  TNF signaling pathway
csab04932  Non-alcoholic fatty liver disease
csab04936  Alcoholic liver disease
csab05010  Alzheimer disease
csab05016  Huntington disease
csab05022  Pathways of neurodegeneration - multiple diseases
csab05132  Salmonella infection
csab05134  Legionellosis
csab05142  Chagas disease
csab05145  Toxoplasmosis
csab05152  Tuberculosis
csab05160  Hepatitis C
csab05161  Hepatitis B
csab05162  Measles
csab05163  Human cytomegalovirus infection
csab05164  Influenza A
csab05165  Human papillomavirus infection
csab05167  Kaposi sarcoma-associated herpesvirus infection
csab05168  Herpes simplex virus 1 infection
csab05169  Epstein-Barr virus infection
csab05170  Human immunodeficiency virus 1 infection
csab05200  Pathways in cancer
csab05203  Viral carcinogenesis
csab05416  Viral myocarditis
csab05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:csab00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04668 TNF signaling pathway
    103217637 (CASP8)
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    103217637 (CASP8)
   04215 Apoptosis - multiple species
    103217637 (CASP8)
   04217 Necroptosis
    103217637 (CASP8)
   04115 p53 signaling pathway
    103217637 (CASP8)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    103217637 (CASP8)
   04621 NOD-like receptor signaling pathway
    103217637 (CASP8)
   04622 RIG-I-like receptor signaling pathway
    103217637 (CASP8)
   04623 Cytosolic DNA-sensing pathway
    103217637 (CASP8)
   04625 C-type lectin receptor signaling pathway
    103217637 (CASP8)
   04657 IL-17 signaling pathway
    103217637 (CASP8)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103217637 (CASP8)
   05203 Viral carcinogenesis
    103217637 (CASP8)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    103217637 (CASP8)
   05161 Hepatitis B
    103217637 (CASP8)
   05160 Hepatitis C
    103217637 (CASP8)
   05164 Influenza A
    103217637 (CASP8)
   05162 Measles
    103217637 (CASP8)
   05168 Herpes simplex virus 1 infection
    103217637 (CASP8)
   05163 Human cytomegalovirus infection
    103217637 (CASP8)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103217637 (CASP8)
   05169 Epstein-Barr virus infection
    103217637 (CASP8)
   05165 Human papillomavirus infection
    103217637 (CASP8)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103217637 (CASP8)
   05134 Legionellosis
    103217637 (CASP8)
   05152 Tuberculosis
    103217637 (CASP8)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103217637 (CASP8)
   05142 Chagas disease
    103217637 (CASP8)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103217637 (CASP8)
   05016 Huntington disease
    103217637 (CASP8)
   05022 Pathways of neurodegeneration - multiple diseases
    103217637 (CASP8)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103217637 (CASP8)
   05416 Viral myocarditis
    103217637 (CASP8)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    103217637 (CASP8)
   04932 Non-alcoholic fatty liver disease
    103217637 (CASP8)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    103217637 (CASP8)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:csab01002]
    103217637 (CASP8)
Enzymes [BR:csab01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.22  Cysteine endopeptidases
    3.4.22.61  caspase-8
     103217637 (CASP8)
Peptidases and inhibitors [BR:csab01002]
 Cysteine peptidases
  Family C14: caspase family
   103217637 (CASP8)
SSDB
Motif
Pfam: Peptidase_C14 DED PYRIN
Other DBs
NCBI-GeneID: 103217637
NCBI-ProteinID: XP_007964024
Ensembl: ENSCSAG00000010781
Position
10:86888654..86944159
AA seq 481 aa
MVPGKGGADYILLPFEEMDFNRNLFDIGEQLDSEELASLKFLSLDCIPQRKQEPIKDALM
LFQRLQEKRMLEENNLSFLKELLFRINRLDLLTTYLNTRKEEMERELQAPGRAQISAYRV
MLYQISEEVGRSELRSFKFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRV
CAQVNKSLLKIINDYEEFSRGEELCGLMTISDSPREQDSESQTLDKVYQMKSKPRGYCLI
INNYDFTKAREKVPKLHSIRDRNGTHLDAEALTATFEELHFEIQHHNDCTVEKIYKILKT
YQLMDHSNKDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQ
ACQGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEG
TWYIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPS
D
NT seq 1446 nt   +upstreamnt  +downstreamnt
atggtgccaggaaagggtggagcggattatattctgctgccttttgaagagatggacttc
aacagaaatctttttgatattggggaacaactggacagtgaagagctggcctccctcaag
ttcctgagcctggactgcatcccacaaaggaagcaagaacccatcaaggatgccttgatg
ttattccagagactccaggaaaagagaatgttggaggaaaacaatctgtccttcctgaag
gagctgctcttccgaattaatagactggatttgctcactacttacctaaacactagaaag
gaggagatggaaagggaacttcaggcaccaggcagggctcagatttctgcctacagggtc
atgctctatcagatttcagaagaggtgggcagatcagaattgaggtcttttaagtttctt
ctgcaagaggagatctccaaatgcaaactggatgatgacatgaacctgctggatattttc
atagagatggagaagagggtcatcctgggagaaggcaagttggacatcctgaaaagagtc
tgtgcccaagtcaacaagagcctgctgaagataatcaatgactacgaagaattcagcaga
ggggaggagttgtgtgggctaatgacaatctcggactctccaagagaacaggatagtgaa
tcacagactttggacaaagtttaccaaatgaaaagcaaacctcggggatactgtctgatc
atcaacaattacgattttacgaaagcacgggagaaagtgcccaaacttcacagcattagg
gacaggaatggaacacacttggatgcagaggctttgaccgcgacctttgaagagcttcat
tttgagatccagcaccacaatgactgcacagtagagaaaatctataagattttgaaaacc
taccaactcatggaccacagtaacaaggattgcttcatctgctgtatcctctcccatgga
gacaagggcatcatctatggcactgatggacaggaagcccccatctatgagctgacatct
cagttcactggtttgaagtgcccttcccttgctggaaaacccaaagtgttttttattcag
gcttgtcagggggataactaccagaaaggtatacccgttgagactgattcagaggagcaa
ccctatttggaaatggatttatcatcacctcaaacgagatatatcccagatgaggctgac
tttctgctggggatggccactgtgaataattgtgtttcctaccgaaaccctgcagaggga
acctggtacatccagtcactttgccagagcctgagagaacgatgtcctcgaggcgatgat
attctcaccatcctgactgaagtgaactatgaagtaagcaacaaggatgacaagaaaaac
atggggaaacagatgccacagccaactttcacactaagaaaaaaactagtcttcccttct
gattga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (36)   
   KEGG PATHWAY (36)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (9)   
   RefSeq(nuc) (9)   
Protein domain (3)   
   Pfam (3)   
All databases (66)   

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