KEGG   Chlorocebus sabaeus (green monkey): 103225637
Entry
103225637         CDS       T04361                                 
Symbol
PIK3CD
Name
(RefSeq) phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
csab  Chlorocebus sabaeus (green monkey)
Pathway
csab00562  Inositol phosphate metabolism
csab01100  Metabolic pathways
csab01521  EGFR tyrosine kinase inhibitor resistance
csab01522  Endocrine resistance
csab01524  Platinum drug resistance
csab04012  ErbB signaling pathway
csab04014  Ras signaling pathway
csab04015  Rap1 signaling pathway
csab04024  cAMP signaling pathway
csab04062  Chemokine signaling pathway
csab04066  HIF-1 signaling pathway
csab04068  FoxO signaling pathway
csab04070  Phosphatidylinositol signaling system
csab04071  Sphingolipid signaling pathway
csab04072  Phospholipase D signaling pathway
csab04140  Autophagy - animal
csab04150  mTOR signaling pathway
csab04151  PI3K-Akt signaling pathway
csab04152  AMPK signaling pathway
csab04210  Apoptosis
csab04211  Longevity regulating pathway
csab04213  Longevity regulating pathway - multiple species
csab04218  Cellular senescence
csab04360  Axon guidance
csab04370  VEGF signaling pathway
csab04380  Osteoclast differentiation
csab04510  Focal adhesion
csab04550  Signaling pathways regulating pluripotency of stem cells
csab04611  Platelet activation
csab04613  Neutrophil extracellular trap formation
csab04620  Toll-like receptor signaling pathway
csab04625  C-type lectin receptor signaling pathway
csab04630  JAK-STAT signaling pathway
csab04650  Natural killer cell mediated cytotoxicity
csab04660  T cell receptor signaling pathway
csab04662  B cell receptor signaling pathway
csab04664  Fc epsilon RI signaling pathway
csab04666  Fc gamma R-mediated phagocytosis
csab04668  TNF signaling pathway
csab04670  Leukocyte transendothelial migration
csab04722  Neurotrophin signaling pathway
csab04725  Cholinergic synapse
csab04750  Inflammatory mediator regulation of TRP channels
csab04810  Regulation of actin cytoskeleton
csab04910  Insulin signaling pathway
csab04914  Progesterone-mediated oocyte maturation
csab04915  Estrogen signaling pathway
csab04917  Prolactin signaling pathway
csab04919  Thyroid hormone signaling pathway
csab04923  Regulation of lipolysis in adipocytes
csab04926  Relaxin signaling pathway
csab04929  GnRH secretion
csab04930  Type II diabetes mellitus
csab04931  Insulin resistance
csab04932  Non-alcoholic fatty liver disease
csab04933  AGE-RAGE signaling pathway in diabetic complications
csab04935  Growth hormone synthesis, secretion and action
csab04960  Aldosterone-regulated sodium reabsorption
csab04973  Carbohydrate digestion and absorption
csab05010  Alzheimer disease
csab05017  Spinocerebellar ataxia
csab05020  Prion disease
csab05100  Bacterial invasion of epithelial cells
csab05132  Salmonella infection
csab05135  Yersinia infection
csab05142  Chagas disease
csab05146  Amoebiasis
csab05160  Hepatitis C
csab05161  Hepatitis B
csab05162  Measles
csab05163  Human cytomegalovirus infection
csab05164  Influenza A
csab05165  Human papillomavirus infection
csab05166  Human T-cell leukemia virus 1 infection
csab05167  Kaposi sarcoma-associated herpesvirus infection
csab05168  Herpes simplex virus 1 infection
csab05169  Epstein-Barr virus infection
csab05170  Human immunodeficiency virus 1 infection
csab05171  Coronavirus disease - COVID-19
csab05200  Pathways in cancer
csab05203  Viral carcinogenesis
csab05205  Proteoglycans in cancer
csab05206  MicroRNAs in cancer
csab05207  Chemical carcinogenesis - receptor activation
csab05208  Chemical carcinogenesis - reactive oxygen species
csab05210  Colorectal cancer
csab05211  Renal cell carcinoma
csab05212  Pancreatic cancer
csab05213  Endometrial cancer
csab05214  Glioma
csab05215  Prostate cancer
csab05218  Melanoma
csab05220  Chronic myeloid leukemia
csab05221  Acute myeloid leukemia
csab05222  Small cell lung cancer
csab05223  Non-small cell lung cancer
csab05224  Breast cancer
csab05225  Hepatocellular carcinoma
csab05226  Gastric cancer
csab05230  Central carbon metabolism in cancer
csab05231  Choline metabolism in cancer
csab05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
csab05415  Diabetic cardiomyopathy
csab05417  Lipid and atherosclerosis
csab05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:csab00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    103225637 (PIK3CD)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    103225637 (PIK3CD)
   04014 Ras signaling pathway
    103225637 (PIK3CD)
   04015 Rap1 signaling pathway
    103225637 (PIK3CD)
   04370 VEGF signaling pathway
    103225637 (PIK3CD)
   04630 JAK-STAT signaling pathway
    103225637 (PIK3CD)
   04668 TNF signaling pathway
    103225637 (PIK3CD)
   04066 HIF-1 signaling pathway
    103225637 (PIK3CD)
   04068 FoxO signaling pathway
    103225637 (PIK3CD)
   04070 Phosphatidylinositol signaling system
    103225637 (PIK3CD)
   04072 Phospholipase D signaling pathway
    103225637 (PIK3CD)
   04071 Sphingolipid signaling pathway
    103225637 (PIK3CD)
   04024 cAMP signaling pathway
    103225637 (PIK3CD)
   04151 PI3K-Akt signaling pathway
    103225637 (PIK3CD)
   04152 AMPK signaling pathway
    103225637 (PIK3CD)
   04150 mTOR signaling pathway
    103225637 (PIK3CD)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    103225637 (PIK3CD)
  09143 Cell growth and death
   04210 Apoptosis
    103225637 (PIK3CD)
   04218 Cellular senescence
    103225637 (PIK3CD)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103225637 (PIK3CD)
   04550 Signaling pathways regulating pluripotency of stem cells
    103225637 (PIK3CD)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103225637 (PIK3CD)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103225637 (PIK3CD)
   04613 Neutrophil extracellular trap formation
    103225637 (PIK3CD)
   04620 Toll-like receptor signaling pathway
    103225637 (PIK3CD)
   04625 C-type lectin receptor signaling pathway
    103225637 (PIK3CD)
   04650 Natural killer cell mediated cytotoxicity
    103225637 (PIK3CD)
   04660 T cell receptor signaling pathway
    103225637 (PIK3CD)
   04662 B cell receptor signaling pathway
    103225637 (PIK3CD)
   04664 Fc epsilon RI signaling pathway
    103225637 (PIK3CD)
   04666 Fc gamma R-mediated phagocytosis
    103225637 (PIK3CD)
   04670 Leukocyte transendothelial migration
    103225637 (PIK3CD)
   04062 Chemokine signaling pathway
    103225637 (PIK3CD)
  09152 Endocrine system
   04910 Insulin signaling pathway
    103225637 (PIK3CD)
   04923 Regulation of lipolysis in adipocytes
    103225637 (PIK3CD)
   04929 GnRH secretion
    103225637 (PIK3CD)
   04915 Estrogen signaling pathway
    103225637 (PIK3CD)
   04914 Progesterone-mediated oocyte maturation
    103225637 (PIK3CD)
   04917 Prolactin signaling pathway
    103225637 (PIK3CD)
   04926 Relaxin signaling pathway
    103225637 (PIK3CD)
   04935 Growth hormone synthesis, secretion and action
    103225637 (PIK3CD)
   04919 Thyroid hormone signaling pathway
    103225637 (PIK3CD)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    103225637 (PIK3CD)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103225637 (PIK3CD)
  09156 Nervous system
   04725 Cholinergic synapse
    103225637 (PIK3CD)
   04722 Neurotrophin signaling pathway
    103225637 (PIK3CD)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103225637 (PIK3CD)
  09158 Development and regeneration
   04360 Axon guidance
    103225637 (PIK3CD)
   04380 Osteoclast differentiation
    103225637 (PIK3CD)
  09149 Aging
   04211 Longevity regulating pathway
    103225637 (PIK3CD)
   04213 Longevity regulating pathway - multiple species
    103225637 (PIK3CD)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103225637 (PIK3CD)
   05206 MicroRNAs in cancer
    103225637 (PIK3CD)
   05205 Proteoglycans in cancer
    103225637 (PIK3CD)
   05207 Chemical carcinogenesis - receptor activation
    103225637 (PIK3CD)
   05208 Chemical carcinogenesis - reactive oxygen species
    103225637 (PIK3CD)
   05203 Viral carcinogenesis
    103225637 (PIK3CD)
   05230 Central carbon metabolism in cancer
    103225637 (PIK3CD)
   05231 Choline metabolism in cancer
    103225637 (PIK3CD)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    103225637 (PIK3CD)
  09162 Cancer: specific types
   05210 Colorectal cancer
    103225637 (PIK3CD)
   05212 Pancreatic cancer
    103225637 (PIK3CD)
   05225 Hepatocellular carcinoma
    103225637 (PIK3CD)
   05226 Gastric cancer
    103225637 (PIK3CD)
   05214 Glioma
    103225637 (PIK3CD)
   05221 Acute myeloid leukemia
    103225637 (PIK3CD)
   05220 Chronic myeloid leukemia
    103225637 (PIK3CD)
   05218 Melanoma
    103225637 (PIK3CD)
   05211 Renal cell carcinoma
    103225637 (PIK3CD)
   05215 Prostate cancer
    103225637 (PIK3CD)
   05213 Endometrial cancer
    103225637 (PIK3CD)
   05224 Breast cancer
    103225637 (PIK3CD)
   05222 Small cell lung cancer
    103225637 (PIK3CD)
   05223 Non-small cell lung cancer
    103225637 (PIK3CD)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    103225637 (PIK3CD)
   05170 Human immunodeficiency virus 1 infection
    103225637 (PIK3CD)
   05161 Hepatitis B
    103225637 (PIK3CD)
   05160 Hepatitis C
    103225637 (PIK3CD)
   05171 Coronavirus disease - COVID-19
    103225637 (PIK3CD)
   05164 Influenza A
    103225637 (PIK3CD)
   05162 Measles
    103225637 (PIK3CD)
   05168 Herpes simplex virus 1 infection
    103225637 (PIK3CD)
   05163 Human cytomegalovirus infection
    103225637 (PIK3CD)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103225637 (PIK3CD)
   05169 Epstein-Barr virus infection
    103225637 (PIK3CD)
   05165 Human papillomavirus infection
    103225637 (PIK3CD)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103225637 (PIK3CD)
   05135 Yersinia infection
    103225637 (PIK3CD)
   05100 Bacterial invasion of epithelial cells
    103225637 (PIK3CD)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103225637 (PIK3CD)
   05142 Chagas disease
    103225637 (PIK3CD)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103225637 (PIK3CD)
   05017 Spinocerebellar ataxia
    103225637 (PIK3CD)
   05020 Prion disease
    103225637 (PIK3CD)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    103225637 (PIK3CD)
   05418 Fluid shear stress and atherosclerosis
    103225637 (PIK3CD)
   05415 Diabetic cardiomyopathy
    103225637 (PIK3CD)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    103225637 (PIK3CD)
   04932 Non-alcoholic fatty liver disease
    103225637 (PIK3CD)
   04931 Insulin resistance
    103225637 (PIK3CD)
   04933 AGE-RAGE signaling pathway in diabetic complications
    103225637 (PIK3CD)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    103225637 (PIK3CD)
   01524 Platinum drug resistance
    103225637 (PIK3CD)
   01522 Endocrine resistance
    103225637 (PIK3CD)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:csab04131]
    103225637 (PIK3CD)
Enzymes [BR:csab01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     103225637 (PIK3CD)
Membrane trafficking [BR:csab04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    103225637 (PIK3CD)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_rbd PI3K_p85B PI3K_C2
Other DBs
NCBI-GeneID: 103225637
NCBI-ProteinID: XP_007978817
Ensembl: ENSCSAG00000000770
UniProt: A0A0D9S8P7
Position
20:complement(122040131..122111397)
AA seq 1044 aa
MPPGVDCPMEFWTKEENQSVVVDFLLPTGVYLNFPVSRNANLSTIKQLLWHRAQYEPLFH
MLSGPEAYVFTCINQTAEQQELEDEQRRLCDVQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLCDPEVNDFRAKMCQFCEEAAARRQQLGWEAWLQYSFPLQLEPSARSWGP
GTLRLPNRALLVNVKFEGSEESFTFQVSTKDVPLALMACALRKKATVFRQPLVEQPEDYT
LQVNGRHEYLYGSYPLCQFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIQGSKVNADERMKLVVQAGLFHGNEMLCKTVSS
SEVSVCSEPVWKQRLEFDINICDLPRMARLCFALYAVIEKAKKARSTKKKSKKADCPIAW
ANFMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPTGTVRSNPNTDSAAALLICLPEVAP
HPVYYPALEKILELGRHSECVHVTEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQMLYLLCSWPELPVLSALELLDFSFPDCHVGSFAIKSL
RKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLDRALANRKIGHFLFWHLRSEMHVPSV
ALRFGLILEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKLSSQKTPKPQTKELMHLCMR
QEAYLEALSHLQSPLDPSTLLAEVCVEQCTFMDSKMKPLWIMYSNEEAGSGGSVGIIFKN
GDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLRSDTIANIQLN
KSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHSDNIM
IRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERFRGYC
ERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFRVKFN
EALRESWKTKVNWLAHNVSKDNRQ
NT seq 3135 nt   +upstreamnt  +downstreamnt
atgccccctggggtggactgccccatggaattctggaccaaggaggagaatcagagcgtc
gtggttgacttcctgctgcccacaggggtctacctgaacttccctgtgtcccgcaatgcc
aacctcagcaccatcaagcagctgctgtggcaccgcgcccagtatgagccactcttccac
atgctcagtggccccgaggcctatgtgttcacctgcatcaaccagacggcggagcagcag
gagctggaggatgagcaacggcgtctgtgcgacgtgcagcccttcctgcccgtgctgcgc
ctggtggcccgcgagggcgaccgcgtgaagaagctcatcaactcgcagatcagcctcctc
atcggcaaaggcctccacgagtttgactccttgtgcgacccagaagtgaacgactttcgt
gccaagatgtgccagttctgcgaggaggcggccgcccgccggcagcagctgggctgggag
gcctggttgcagtacagcttccccctgcagctggagccctcggctcgaagctgggggcct
ggcaccctgcggctcccaaaccgggccctcctggtcaacgtcaagtttgagggcagcgag
gagagcttcaccttccaggtgtccaccaaggacgtgccgctggcgctgatggcctgtgcc
ctgcggaagaaggccacggtgttccggcagccgctggtggagcagccggaagactacacg
ctgcaggtgaacggcaggcatgagtacctgtacggcagctacccgctctgccagttccag
tacatctgcagctgcctgcacagtgggctgacccctcacctgaccatggtccattcctcc
tccatcctcgccatgcgggatgagcagagcaaccctgccccccaggtccagaaaccacgt
gccaagccgcctcccattcctgcaaagaagccctcctctgtgtccctgtggtccctggag
cagccgttctgcatcgagctcatccagggcagcaaagtgaacgccgacgagcggatgaag
ctggtggtgcaggcagggcttttccacggcaacgagatgctatgcaagacagtgtccagc
tcggaggtgagcgtgtgctcggaacctgtgtggaagcagcggctggagttcgacatcaac
atctgcgacctgccccgcatggcccgtctttgctttgcactgtacgccgtgatcgagaaa
gccaagaaggcccgctccaccaagaagaagtccaagaaggcggactgccccattgcctgg
gccaacttcatgctgtttgactacaaggaccagcttaagactggggaacgctgtctctac
atgtggccctccgtcccagatgagaagggcgagctgctgaaccccacaggcactgtgcgt
agtaaccccaacacggatagcgctgccgccctgctcatctgcctgcctgaggtggccccg
caccccgtgtactatcccgccctggagaagatcttggagctggggcggcacagtgagtgt
gtacatgtcaccgaggaggagcagctgcagctgcgggaaatcctggagcggcgggggtct
ggggagctgtatgagcatgagaaggacctggtgtggaagctgcggcacgaagtccaggag
cacttcccagaggcgctagcccggctgctgctggtcaccaagtggaacaagcacgaggat
gtggcccagatgctctacctgctgtgctcctggccggagctgcctgtcctgagcgccctg
gagctgctggacttcagcttccctgattgccacgtaggctcctttgccatcaagtcgctg
cggaaactgacggacgatgagctgttccagtacttgctgcagctggtgcaggtgctaaag
tacgagtcctacctggactgcgagctgaccaaattcctgctggaccgggccctggccaac
cgcaagatcggccacttccttttctggcacctccgctccgagatgcacgtgccgtcggtg
gccctgcgcttcggcctcatcttggaggcctactgcaggggcagcacccaccacatgaag
gtgctgatgaagcagggggaagcactgagcaaactgaaggcactgaacgacttcgtcaag
ctgagctctcagaagacccccaagccccagacgaaggagctgatgcacttgtgcatgcgg
caggaggcctacctagaggccctctcccacctgcagtccccactcgaccccagcaccctg
ctggctgaagtctgtgtggagcagtgcaccttcatggactccaagatgaagcccctgtgg
atcatgtacagcaacgaggaggcaggcagtggtggcagcgtgggcatcatctttaagaac
ggggatgacctccggcaggacatgctgaccctgcagatgatccagctcatggacgtcctg
tggaagcaggaggggctggacctgaggatgaccccctatggctgcctccccaccggggac
cgcacaggcctcattgaggtggtactccgctcagacaccattgccaacatccaactcaac
aagagcaacatggcagccacagccgccttcaacaaggatgccctgctcaactggctgaag
tccaagaacccaggggaggccctggatcgagccattgaggagttcaccctctcctgtgct
ggctactgtgtggccacatacgtgctgggcatcggcgatcggcacagcgacaacatcatg
atccgagagagtgggcagctgttccacattgattttggccactttctggggaatttcaag
accaagtttggaatcaaccgcgagcgtgtcccgttcatcctcacctatgactttgtccat
gtgattcagcaggggaagactaataacagtgagaaatttgaaaggttccggggctactgt
gaaagggcctacaccatcctacggcgccacgggcttctcttcctccacctctttgccctg
atgcgggcagcaggcctgcctgagctcagctgctccaaagacatccagtacctcaaggac
tccctggcactggggaaaacagaggaggaggcgctgaagcacttccgagtgaagtttaat
gaagccctccgtgagagctggaaaaccaaagtgaactggctggcccacaatgtgtccaag
gacaacaggcagtag

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (105)   
   KEGG PATHWAY (105)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (5)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (9)   
   UniProt (1)   
   RefSeq(pep) (8)   
DNA sequence (8)   
   RefSeq(nuc) (8)   
Protein domain (5)   
   Pfam (5)   
All databases (142)   

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