KEGG   Drosophila melanogaster (fruit fly): Dmel_CG11561
Entry
Dmel_CG11561      CDS       T00030                                 
Symbol
smo
Name
(RefSeq) smoothened
  KO
K06226  smoothened
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme04341  Hedgehog signaling pathway - fly
Brite
KEGG Orthology (KO) [BR:dme00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04341 Hedgehog signaling pathway - fly
    Dmel_CG11561 (smo)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors [BR:dme04030]
    Dmel_CG11561 (smo)
G protein-coupled receptors [BR:dme04030]
 Frizzled / Smoothened family
  Dmel_CG11561 (smo)
SSDB
Motif
Pfam: Frizzled Fz Penicillinase_R DUF6688 DUF373
Other DBs
NCBI-GeneID: 33196
NCBI-ProteinID: NP_523443
FlyBase: FBgn0003444
UniProt: P91682
Structure
Position
2L
AA seq 1036 aa
MQYLNFPRMPNIMMFLEVAILCLWVVADASASSAKFGSTTPASAQQSDVELEPINGTLNY
RLYAKKGRDDKPWFDGLDSRHIQCVRRARCYPTSNATNTCFGSKLPYELSSLDLTDFHTE
KELNDKLNDYYALKHVPKCWAAIQPFLCAVFKPKCEKINGEDMVYLPSYEMCRITMEPCR
ILYNTTFFPKFLRCNETLFPTKCTNGARGMKFNGTGQCLSPLVPTDTSASYYPGIEGCGV
RCKDPLYTDDEHRQIHKLIGWAGSICLLSNLFVVSTFFIDWKNANKYPAVIVFYINLCFL
IACVGWLLQFTSGSREDIVCRKDGTLRHSEPTAGENLSCIVIFVLVYYFLTAGMVWFVFL
TYAWHWRAMGHVQDRIDKKGSYFHLVAWSLPLVLTITTMAFSEVDGNSIVGICFVGYINH
SMRAGLLLGPLCGVILIGGYFITRGMVMLFGLKHFANDIKSTSASNKIHLIIMRMGVCAL
LTLVFILVAIACHVTEFRHADEWAQSFRQFIICKISSVFEEKSSCRIENRPSVGVLQLHL
LCLFSSGIVMSTWCWTPSSIETWKRYIRKKCGKEVVEEVKMPKHKVIAQTWAKRKDFEDK
GRLSITLYNTHTDPVGLNFDVNDLNSSETNDISSTWAAYLPQCVKRRMALTGAATGNSSS
HGPRKNSLDSEISVSVRHVSVESRRNSVDSQVSVKIAEMKTKVASRSRGKHGGSSSNRRT
QRRRDYIAAATGKSSRRRESSTSVESQVIALKKTTYPNASHKVGVFAHHSSKKQHNYTSS
MKRRTANAGLDPSILNEFLQKNGDFIFPFLQNQDMSSSSEEDNSRASQKIQDLNVVVKQQ
EISEDDHDGIKIEELPNSKQVALENFLKNIKKSNESNSNRHSRNSARSQSKKSQKRHLKN
PAADLDFRKDCVKYRSNDSLSCSSEELDVALDVGSLLNSSFSGISMGKPHSRNSKTSCDV
GIQANPFELVPSYGEDELQQAMRLLNAASRQRTEAANEDFGGTELQGLLGHSHRHQREPT
FMSESDKLKMLLLPSK
NT seq 3111 nt   +upstreamnt  +downstreamnt
atgcagtacttaaactttccgcgcatgccaaacattatgatgttcctggaggttgcgatc
ttatgcctgtgggtggtcgcagacgcatcggccagttcggccaagttcggcagcacaacg
cccgcaagtgcgcagcagtcggatgtggaactggagcccatcaatgggactctcaattac
cgactgtacgccaagaagggcagggacgacaaaccctggtttgatggcctagacagcagg
cacatccagtgtgtccgacgtgcccgttgctaccccacctcgaacgcaaccaacacctgt
ttcggctcaaaattgccctatgagctgagcagcctagatctcaccgacttccacaccgaa
aaggagctgaacgataagctgaacgactactatgccctgaagcacgtgcccaaatgttgg
gcagctatacagccctttttgtgcgccgtctttaagccgaagtgtgaaaaaatcaacggc
gaggacatggtctacctgccatcttacgagatgtgccgaattaccatggaaccctgtcgc
attttgtacaacacgacgtttttcccaaaattccttcgctgcaacgaaacactctttccg
acgaaatgcacaaacggagcacgaggaatgaaattcaacggaactggccagtgtttaagt
cctttggttccgacagatacgtcagccagctattatcctggcatcgagggctgcggcgtg
cgatgcaaggatccactctataccgatgatgagcatcggcagatccacaaactgatcgga
tgggctggcagcatatgtcttctgtctaaccttttcgtggtgtccaccttcttcatcgac
tggaagaatgccaacaagtatccggcagtaattgtgttctacataaatctttgctttcta
attgcttgcgtcggctggttgcttcagtttacttctggctcgcgagaggacatagtatgt
cgtaaggatggaacacttcgccactcagagcctacagccggtgaaaatctttcttgcata
gtgatctttgtgctggtctattattttctcaccgctggaatggtttggtttgtgttcctc
acctacgcctggcattggagggccatgggccacgtccaagatcggatagataagaaaggt
tcctactttcacctcgtggcgtggtcactaccccttgtgcttaccattaccacgatggct
ttcagtgaggtggatggaaatagtattgtgggcatctgcttcgtaggctatatcaatcat
tctatgagggcaggactacttcttggtccgctctgcggggtcatcctcattggtggatac
ttcatcacccgcggcatggtgatgctttttggactgaaacacttcgctaatgacattaaa
tcaacttcggcgagcaacaaaatccatttgatcatcatgcgcatgggagtctgtgctctg
ctcactttagttttcatactagtggccattgcgtgccacgttacggagtttaggcatgca
gacgaatgggcccagagcttcagacagtttataatctgcaaaatttcttcagtttttgaa
gaaaagagttcctgtcgaattgaaaaccgacctagtgttggcgttcttcaattgcatttg
ctgtgtctatttagctctggaatcgtaatgtccacctggtgctggacaccttcttcaatt
gagacttggaagcgttatataaggaaaaagtgtggcaaagaggtggtcgaagaagtgaaa
atgccgaagcacaaggtcattgcccagacatgggccaagcgcaaggatttcgaggacaag
ggcaggctctccataacgctctacaacacccacacagatcccgtggggctcaacttcgat
gtgaacgatctgaactcttctgagacgaatgacatctcatcaacttgggctgcatacctc
ccgcagtgcgtaaaacgtcgcatggctttgacgggagcagcgacaggtaactcgtcaagc
catggaccgcgaaaaaattcattggattccgagataagtgtgagtgttcgacatgtttcc
gttgaatcccgcagaaattcggtggactcgcaggtatcagtgaaaatagctgaaatgaag
accaaagtggcgtccagatcaaggggaaaacacggaggctcttccagcaacagaagaacc
caaaggagaagggattatatagcagctgccactggaaaaagcagtaggagaagggaaagc
agtacttcagtggagtcgcaggtcatcgcgctcaagaaaacgacctatcccaatgctagt
cacaaagtgggcgtgtttgctcatcacagctccaagaaacaacacaattacaccagctcc
atgaagcgaaggactgctaatgccggattggatccctctattcttaatgaattcctgcag
aaaaatggcgattttatattcccattcctccaaaatcaagatatgagctctagttcggag
gaggataattccagagcatcccaaaagattcaggatcttaacgtggttgtaaagcagcag
gaaataagtgaggatgatcacgacggaataaagattgaagaactgccaaatagcaaacag
gtggcattggagaactttcttaaaaacataaaaaaatctaatgaatccaattctaaccga
cattcccgaaattccgcaagaagtcagtcaaaaaagtcccaaaagagacatctcaagaac
cctgctgctgatctagatttcaggaaggactgtgtaaagtatcggtctaatgactcactt
agctgctcctctgaagagctggatgtggctttggacgtaggaagccttcttaacagctct
ttttctggaatatccatgggcaaaccacatagtagaaacagcaaaaccagctgcgatgtg
ggcatacaggctaatcctttcgagctagttcccagttacggagaagacgaactgcagcag
gccatgcgactcctaaacgcagccagcagacaaagaactgaagcagccaatgaggatttc
ggaggaacggagctgcagggcttgttgggtcattcccatcggcatcaaagggagcccacg
tttatgagcgagtcggacaaactcaaaatgttattgctgccttcaaaatag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (1)   
   KEGG PATHWAY (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (68)   
   KEGG ORTHOLOGY (1)   
   RefGene (63)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (5)   
   Pfam (5)   
All databases (83)   

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