KEGG   Drosophila melanogaster (fruit fly): Dmel_CG12306
Entry
Dmel_CG12306      CDS       T00030                                 
Symbol
polo
Name
(RefSeq) polo, isoform B
  KO
K06631  polo-like kinase 1 [EC:2.7.11.21]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme04068  FoxO signaling pathway
Brite
KEGG Orthology (KO) [BR:dme00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    Dmel_CG12306 (polo)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dme01001]
    Dmel_CG12306 (polo)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dme03036]
    Dmel_CG12306 (polo)
Enzymes [BR:dme01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.21  polo kinase
     Dmel_CG12306 (polo)
Protein kinases [BR:dme01001]
 Serine/threonine kinases: Other
  PLK family [OT]
   Dmel_CG12306 (polo)
Chromosome and associated proteins [BR:dme03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     Dmel_CG12306 (polo)
  Centrosome formation proteins
   Kinases and associated factors
    Dmel_CG12306 (polo)
  Sister chromatid separation proteins
   Polo kinases
    Dmel_CG12306 (polo)
SSDB
Motif
Pfam: Pkinase POLO_box PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal
Other DBs
NCBI-GeneID: 40232
NCBI-ProteinID: NP_001014592
FlyBase: FBgn0003124
UniProt: P52304
Position
3L
AA seq 576 aa
MAAKPEDKSTDIPDRLVDINQRKTYKRMRFFGKGGFAKCYEIIDVETDDVFAGKIVSKKL
MIKHNQKEKTAQEITIHRSLNHPNIVKFHNYFEDSQNIYIVLELCKKRSMMELHKRRKSI
TEFECRYYIYQIIQGVKYLHDNRIIHRDLKLGNLFLNDLLHVKIGDFGLATRIEYEGERK
KTLCGTPNYIAPEILTKKGHSFEVDIWSIGCVMYTLLVGQPPFETKTLKDTYSKIKKCEY
RVPSYLRKPAADMVIAMLQPNPESRPAIGQLLNFEFLKGSKVPMFLPSSCLTMAPRIGSN
DTIEDSMHRKPLMEMNGIRPDDTRLESTFLKANLHDAITASAQVCRHSEDYRSDIESLYQ
QLTNLINGKPRILQGNLGDENTDPAAQPLFWISKWVDYSDKYGFGYQLCDEGIGVMFNDT
TKLILLPNQINVHFIDKDGKETYMTTTDYCKSLDKKMKLLSYFKRYMIEHLVKAGANNVN
IESDQISRMPHLHSWFRTTCAVVMHLTNGSVQLNFSDHMKLILCPRMSAITYMDQEKNFR
TYRFSTIVENGVSKDLYQKIRYAQEKLRKMLEKMFT
NT seq 1731 nt   +upstreamnt  +downstreamnt
atggccgcgaagcccgaggataagagcacggatattccggatcgcctcgtcgacatcaac
cagcggaaaacctacaagcgcatgcggttcttcggcaagggcgggtttgcaaaatgttac
gagatcatcgatgtggaaaccgacgacgtcttcgccggcaagatcgtatccaagaagctg
atgatcaaacacaatcagaaggagaagaccgcccaggagataactattcaccgcagcctt
aaccatccgaacattgtcaagtttcacaactactttgaagattcgcagaatatctacatt
gtgctggagctgtgcaagaaaagatccatgatggagctgcacaaacgtaggaaaagcatt
acggagttcgaatgccgctactacatttaccagataatccagggcgttaagtacttgcac
gataaccgcattatccatcgagatctgaagctgggcaatctcttcctcaacgatttgttg
cacgtgaagatcggggatttcgggttggccacgcgcattgagtatgagggcgagcgaaaa
aagaccttatgcggaacgcccaactatatagccccggagatcctcaccaagaagggccac
tccttcgaggtggacatctggtcgattggctgcgtcatgtacacactgcttgtgggccag
ccgccgttcgaaaccaagactctgaaggatacgtactcgaaaatcaagaagtgcgagtac
cgcgtgcccagctacttaaggaaaccggcggcggatatggtcatcgccatgctgcagcca
aatccggagagccgcccggcaattggtcagctgctgaactttgagttcctcaagggctca
aaggtgcccatgttcttgcccagctcttgtctgacaatggcgccgcgtatcggcagcaac
gacaccatcgaggattcgatgcaccgcaagccactgatggagatgaacggcatcaggccc
gacgacactcgtctggagtcgaccttcctcaaggccaatctgcacgacgccattaccgcg
tcagcgcaggtgtgccgccacagcgaggactatcgcagcgatatcgagagcctgtaccag
cagctcactaatcttatcaacggaaagccgcgaattctgcaaggcaatctgggcgacgag
aacacagatcctgcagcgcagccgctcttctggatatccaagtgggttgactacagcgac
aagtacggatttggttaccagctgtgcgatgagggcatcggcgtgatgttcaacgacacc
acaaagctgatcctgctgccgaatcagatcaacgtacacttcatcgacaaggatggcaag
gagacgtacatgaccaccacggattactgcaagtcgcttgacaagaagatgaagctgctg
tcgtactttaagcgctacatgatcgagcacctggtgaaggcaggtgccaacaatgtgaac
attgagagcgatcaaatctcgcgtatgccccatttacactcctggttccgtacaacatgt
gccgtagttatgcatttgaccaacggttctgtgcagctaaacttctcagatcacatgaag
ctcatcctctgcccgcgcatgagtgctataacctatatggaccaggagaagaacttccgc
acctaccgattttcgaccattgtggagaacggcgtgtctaaagacttgtaccagaagatc
cgatatgcccaggagaaacttaggaaaatgctggagaagatgttcacataa

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Ontology (4)   
   KEGG BRITE (4)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (28)   
   KEGG ORTHOLOGY (1)   
   RefGene (23)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (5)   
   Pfam (5)   
All databases (46)   

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