KEGG   Drosophila melanogaster (fruit fly): Dmel_CG3523
Entry
Dmel_CG3523       CDS       T00030                                 
Symbol
FASN1
Name
(RefSeq) fatty acid synthase 1, isoform C
  KO
K00665  fatty acid synthase, animal type [EC:2.3.1.85]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme00061  Fatty acid biosynthesis
dme01100  Metabolic pathways
dme01212  Fatty acid metabolism
Module
dme_M00082  Fatty acid biosynthesis, initiation
dme_M00083  Fatty acid biosynthesis, elongation
Brite
KEGG Orthology (KO) [BR:dme00001]
 09100 Metabolism
  09103 Lipid metabolism
   00061 Fatty acid biosynthesis
    Dmel_CG3523 (FASN1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01004 Lipid biosynthesis proteins [BR:dme01004]
    Dmel_CG3523 (FASN1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dme04147]
    Dmel_CG3523 (FASN1)
Enzymes [BR:dme01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.85  fatty-acid synthase system
     Dmel_CG3523 (FASN1)
Lipid biosynthesis proteins [BR:dme01004]
 Fatty acid synthase
  Animal type
   Dmel_CG3523 (FASN1)
Exosome [BR:dme04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   Dmel_CG3523 (FASN1)
  Exosomal proteins of breast milk
   Dmel_CG3523 (FASN1)
  Exosomal proteins of colorectal cancer cells
   Dmel_CG3523 (FASN1)
  Exosomal proteins of bladder cancer cells
   Dmel_CG3523 (FASN1)
SSDB
Motif
Pfam: Acyl_transf_1 ketoacyl-synt KR KAsynt_C_assoc Ketoacyl-synt_C FAS_pseudo-KR Thioesterase ADH_zinc_N_2 ADH_zinc_N PKS_DH_N PP-binding ACP_syn_III adh_short PS-DH
Other DBs
NCBI-GeneID: 33524
NCBI-ProteinID: NP_001137778
FlyBase: FBgn0283427
UniProt: B7Z001
Position
2L
AA seq 2540 aa
MPLQLNLLQAVDQPHPVAFKPNNCSTHQPQHSPSTQNNGKSARANRRRRRRRNKQQQNSQ
QPDAFRDTDAQLTPSTSSSTPHSAPNDRQDHLNSQFNPESINMPARFAEEVITAEPAQRA
APQLDLGGGHYVPRQQHLNDEIAITGFSGRLPESSTIEEFKQNLFDGVDMVNDDPRRWER
GLYGLPDRIGKLKDSDLENFDQQFFGVHQKQAECMDPLLRMLLELTHEAIIDAGLNPSDL
RGSRTGVYIGVSNSETEQHWCSDADRVNGYGLTGCARAMFANRISFTFDFKGPSYSIDTA
CSSSLYALEQAFSDMREGKVDNALVAGAGLILKPTMSLQFKRLNMLSPDGSCKAFDESGN
GYVRSDGCVVLLLQRTSAARRVYASILNVRTNTDGFKEQGITYPIGKMQNRLIRETYEEI
GLNPADVVYVEAHGTGTKVGDPQEVNSITDFFCKDRTTPLLIGSVKSNMGHSEPASGVCS
VAKILIAMEEGVIPGNLHYNKPNPDLYGLVDGRLKVVDRNLPWNGGIIGLNSFGFGGANA
HVILKSNPKPKALTPKDGALKVVLASGRTFEAVEQLLESASTNADDDEYLQLINEIHSKA
IPNHFFRGYGVVSSKGTHQREVIESNDDKRPIWYIYSGMGSQWASMAKDLMKIEAFAKTI
QRCADVLKPEGVDLIDVLTRSTDKSFENILNSFISIAAMQVALTDLLSSLGIHPDGIVGH
SVGELGCAYADGCFTPEQTVLAAYWRGKSILDTQLAKGKMAAVGLSWEDAHSRVPSDCFP
VCHNSEDNCTISGPEASIEALVAKLNAEGVFAKAVNSSGYAFHSKYIAEAGPKLRKSLEK
IIPNAKNRTARWISTSIPESAWNTPVAKQSSAAYHVNNLLSPVLFHEALQHVPKNAISVE
IAPHGLLQAILKRALGPDATNLSLVKRGHENNVEFFLTNVGKLFAAGAQPQVLTLVRPIS
YPVGRGTPMLNSKVGWDHTQKWLVAKFGKETSSGETIVEVDLSKEDDAFLAGHTIDGRIL
FPATGYMTLAWQTFAKMQGSEFHKTPVVMENLVFHRATILNKNAVVKFGINFFDGTGAFE
ICESGSLAVSGKITIPESIDNEELPLEEQTPSAVAKELGTNDVYKELRLRGYDYGGIFRG
IVRSDTVASTGKLQWVDNWISFMDTMLQFSILSKNLRELYLPTRIERAVINPAKHFELLS
ALTKEEQVETGLPVQWYSDINVIKSAGVELRGLKANLAQRRPGTQAPPTLERYQFVPNIN
TTDLNENSEKARLHALDVAIQVIIENSSGAVKLKGVELANGRNPDVLVANRLLQIIEGEP
VLTGDVAVVTSNNNEETITAALGDSGVRVVSKDVLKEPVEQNCHFVFGIDVLSRPDTKTL
ENSIASIRENGFLILEETLPTYTKTGRALLTKFGFVAVQEQSLGATRVLVLARKAVDLKT
RKSVVVVATEQNFNWVDDLKAALATAATEEQYVYVVCQGEELFGAVGLMTCIKNENGGKL
ARLVFVQDAKAEKFSLTSTLYRQQLEKDLISNVLKNGAWGTFRHLKLETQQATLQVEHAY
VNALVKGDLASLKWIEAAQADTAATVDKNLETCTVYYAPINFRDVMLTSGKLAADALPGD
LAEQDCVLGLEFAGRDTQGRRVMAMVPAKSLATTCVASKRMMWQIPEKWTMEEASTVPCV
YSTVYYALVVRGQMKKGEKILIHAGSGGVGQAAISVALAHGLTVFTTVGSKEKREFLLKR
FPKLQERNIGNSRDTSFEQLVLRETKGRGVDLVLNSLSEEKLQASIRCLGLNGRFLEIGK
FDLSNNSPLGMSVFLKNTSFHGILLDSVMEGEEEMQNQVVSLVAEGIKTGAVVPLPTSVF
NDQQVEQAFRFMASGKHIGKVVIKVRDEEAGKKALQPKPRLINAIPRTYMHPEKSYILVG
GLGGFGLELTNWLVTRGARYIVLTSRSGVKTGYQGLMIRRWQERGVKVVIDTSDVTTAAG
AKKLLENSNKLALVGGIFNLAAVLRDALIEDQTAKDFKTVADPKVTATKYLDQFSRDICT
ELDYFICFSSVSCGRGNIGQTNYGLANSAMERICEQRQVSGFPGTAIQWGAIGDTGLVLE
NLGDNDTVIGGTLPQRMPSCLQTIDLFLQQPHPVVASMVVAEKRKSDQSAGVSLIATIAN
ILGLRDTKNIQDGASLADLGMDSLMSAEIKQTLERNFDIVLSAQEIRQLTFGALKAMDGG
ADVKPAAAAPAAAAGVPEANITSGGSSRTASPMGDGTQVVFTTSLIPTEAIVQLDTKAPA
NSKQSPIFFISPIEGFASALEPLAKRLEVPAYGLQYTEAVPSDSLESAAKFFIKQLRTVQ
PKGPYKLAGYSFGCLLTYVMAGILEETNEVANVIMLDGAPSYVNWYTSSFKQRYTDGTNA
DNDNQSYGLAYFGIVLANIDYKALVRLLIVIPTWEEKLERFAELMSNEITQPVETIKKSA
TLFYKKLELADGYQPTLKLKTNVTLVKPTDNSAKLDEDYRLKEVCTKPVEVHTVEGNHRT
FLIEDQSLKTIQSILKRLFN
NT seq 7623 nt   +upstreamnt  +downstreamnt
atgcccctacaactaaacctgttgcaagccgtggaccagccgcatcctgttgctttcaag
cccaacaattgcagcacccatcagccccaacattcacccagcacccagaacaacggaaag
agcgctcgcgccaatcgtcgtcgacgccgcagacgcaacaagcagcagcagaattcgcag
caacctgacgccttccgtgataccgacgcgcagctaacaccgagcacctcctcgtccacc
ccgcactctgcacccaacgatagacaggaccacctaaactcccaattcaatcccgaatcc
atcaatatgcccgcccgattcgccgaggaagtcatcaccgctgagcccgcacaacgtgcc
gccccccaattggacctgggtggtggtcactatgtgccccgtcagcagcacctcaacgat
gagatcgccatcaccggtttctccggccgtctgccggagagctccaccatcgaggagttc
aagcagaatcttttcgacggcgtcgacatggtcaacgatgatccccgccgttgggagcgt
ggtctgtatggacttcccgacaggattggcaagctcaaggatagcgatctggagaacttt
gaccaacagttcttcggtgtgcaccaaaagcaggctgagtgcatggacccactgctgcgc
atgctgctcgagctcacccatgaagctattattgacgctggcctaaacccaagtgatctg
cgcggttcccgcactggtgtgtacatcggtgtgtccaactcggagactgagcagcactgg
tgcagcgatgctgaccgggttaacggctacggcttgacaggatgtgcccgtgccatgttt
gccaaccgcatctccttcacctttgatttcaagggacccagctacagcattgacaccgct
tgctccagttctctgtacgccttggaacaggctttctccgatatgcgcgaaggaaaggtc
gacaacgccctggtcgctggagctggactgatcctcaagcccaccatgtcgctgcagttc
aagcgactgaatatgttgagcccggacggcagctgcaaggccttcgatgagtctggcaat
ggatacgtccgttccgatggatgtgtggtgctgctcctgcagcgcacctctgcagccagg
cgtgtgtatgcctccatcctcaatgtgcgcaccaatacggatggtttcaaggagcagggc
atcacataccctattggcaagatgcaaaatcgcctgatccgcgagacctacgaggagatt
ggtcttaaccccgccgatgtggtttacgtggaggcacacggtaccggaaccaaggtgggc
gatccccaggaggtgaactctatcactgacttcttctgcaaggaccgtacgacccctctg
ttgatcggatcggtcaagtccaacatgggtcactcggaacccgcttccggtgtctgctct
gtggccaagattctgatcgccatggaggagggcgtcattcccggtaacttgcactacaac
aagccgaacccagatctttatggactcgttgatggacgtctcaaggtggtcgacaggaat
ctgccttggaacggtggcatcatcggcctgaactcctttggttttggaggagccaacgct
cacgttatcttaaagtcgaaccccaagcccaaggctttgacccccaaggatggagcactg
aaagtggtcctcgcctctggacgcacctttgaggctgtggagcagttgctcgagtccgcc
tctactaatgccgatgatgatgagtacctgcaactgatcaacgagatccactcaaaggct
attccgaatcacttcttccgtggctacggagtggtgagcagcaagggcacccaccaacgt
gaggtgatcgagtccaacgacgataaacgccctatttggtacatctactccggcatgggc
agccagtgggctagcatggccaaggatctgatgaagatcgaggccttcgccaagaccatt
cagaggtgtgccgatgtcctaaagcccgagggagtggatctaatcgatgtcctgacccgt
tccacggacaagagcttcgaaaacattctgaactctttcatctcgattgctgccatgcaa
gtggctcttaccgatttgctcagctcgctgggcatccaccccgacggaattgtgggacac
tcggtgggagagcttggatgcgcctacgccgatggctgcttcaccccggagcagaccgtg
ctggctgcttactggcgaggaaagagcattctggacactcaactggccaagggcaagatg
gccgctgtgggattgagctgggaagatgcgcacagccgtgtgcccagcgattgcttcccg
gtgtgccacaacagcgaggacaactgcaccatctctggcccggaggcttccatcgaggct
ctggtcgctaaactgaacgcggagggagtgttcgccaaggcagtgaactcatccggctac
gctttccacagcaagtacatcgctgaagctggacccaaactacgcaagagtctggagaag
atcattcccaacgctaagaaccgtaccgcccgctggatcagtaccagcatcccagaatcc
gcttggaacacaccggtggccaagcaatcctcggccgcctaccacgtgaacaatctgctg
tcgccagtgctcttccacgaggcccttcagcacgttcccaagaacgccatttccgtggag
attgctccccacggcctgctccaggctatcctcaagcgcgccctgggtcctgatgccacc
aatctgagcttggtgaagcgcggacacgagaacaacgttgagttcttcctcaccaatgtg
ggcaaactctttgccgccggagcccagcctcaggtacttactctagtgcgtcctatcagc
tacccggtgggtcgtggaacccccatgttgaactccaaggtcggatgggaccacacccag
aagtggctggtggccaagttcggcaaggaaacttcttctggtgagaccatcgtggaagtc
gatctctccaaggaggatgatgctttcctggctggacacacgatcgacggacgtatcctc
ttcccggccactggctacatgactctggcttggcagacattcgctaagatgcagggaagt
gagttccacaagaccccggtggtaatggagaacctcgtgttccaccgtgccactattctt
aacaagaacgcagtggtcaagtttggcattaacttcttcgatggaactggcgcttttgag
atttgtgagagcggtagcttggcggtttctggaaaaataaccattccagagtctattgac
aacgaggagttgcccctggaggagcaaactcccagcgctgttgccaaggagctaggcacc
aacgatgtctacaaggagctgcgcctccgaggctacgactatggtggaattttccgcggc
attgttcgttctgacaccgtggcctccactggaaagcttcagtgggtggacaactggatt
agtttcatggacaccatgttgcagttcagtatccttagcaagaaccttcgtgagctgtac
ctgcccactcgcatcgagcgagcggtgattaatcccgccaagcactttgaattgctgagc
gccctcaccaaggaggaacaggttgagactggactacctgtgcagtggtacagcgacatt
aacgtgatcaagagtgcgggcgtggagctgcgcggtctaaaggccaatctcgcccagcgt
cgtcctggcacacaggcacctcccactctggagcgctaccagtttgtgcccaacatcaac
accacggatctaaatgaaaactctgagaaggctcgcctgcacgccttggatgtggccatc
caggtgatcatcgagaactccagcggagccgtcaagctaaagggcgtggaattggccaat
ggacgcaaccccgacgttttggttgccaaccgcctgctgcagattatcgagggtgagccc
gtgcttactggtgatgtggctgtggtcacctcgaacaacaatgaagagaccataaccgcc
gccctaggagattcaggagttcgagtggtgtccaaggacgtgctgaaggaaccggtagag
cagaactgtcacttcgtctttggcatcgatgtcctttcccgaccggacaccaagaccctg
gagaactccattgccagcattcgcgagaacggtttcctgatccttgaggagacgctgccc
acttacaccaagacaggccgtgccctgctgaccaaatttggattcgttgccgttcaggaa
cagagtctgggagccacccgtgtcctggtcctcgcccgcaaggctgttgatctgaaaact
cgcaagtccgttgtggttgtggccaccgagcagaactttaactgggtggatgacttgaag
gccgctctggctactgctgctacggaggagcagtatgtgtacgtggtttgccagggagag
gagctgtttggagctgtgggtctgatgacgtgcatcaagaacgagaatggcggcaaactg
gctcgcctggtcttcgtgcaagatgccaaggctgagaagttctcccttacatcgaccctg
taccgccagcagctggagaaggacctcatctcgaacgtgctgaagaacggcgcttggggc
actttccgtcacctgaaactggagacccagcaggccactctccaagtggagcatgcctat
gtaaacgctctggtcaagggtgatcttgcttccctcaagtggatcgaggctgcccaggcg
gataccgctgcaactgtcgacaagaacctggaaacttgcaccgtctactatgcgcccatc
aacttccgtgacgttatgttgacctctggtaagctggccgcggatgccttgcctggagat
ctggctgagcaagattgtgtgctgggtctggagttcgctggtcgcgatacccagggtcgt
cgtgtaatggccatggtgccggctaaatcacttgctaccacctgcgtggcaagcaagcgc
atgatgtggcaaatccctgagaagtggaccatggaagaggcttcgaccgttccttgcgtg
tactccaccgtctactacgctctggttgtgcgaggacaaatgaagaagggtgagaagatc
ctcattcacgctggctccggaggagttggtcaggcggccatctctgtggctctggcccat
ggcttgaccgtgttcaccacggtgggcagcaaggaaaagcgcgagttcctgctgaagcga
ttccccaaactgcaggagcgtaacatcggcaactcccgagacacctccttcgagcagttg
gtcctgcgcgagaccaagggacgcggagtcgatctggtgctgaactcgttatctgaagag
aaactgcaggcctcgatccgctgtttgggtctgaatggacgcttcctggagattggcaag
ttcgatttgagcaacaacagcccacttggaatgtccgttttcctcaagaacacctccttc
cacggcattttgcttgacagtgtgatggagggcgaggaggagatgcaaaaccaggttgtc
tccctggtcgctgagggcatcaagaccggagccgttgtaccccttccgacctcggtgttt
aacgaccagcaggtggagcaggccttccgtttcatggcctctggcaagcacatcggcaag
gtagtgatcaaggtgcgtgatgaggaggcaggcaagaaggcgctgcagcccaagccgcgc
ctgatcaacgccattccacgcacatacatgcacccggagaagagttacatcctggttgga
ggtcttggcggattcggtttggagctgaccaactggttggtgacgcgtggagcccgctac
attgtgctgacctctcgttccggagttaagaccggctaccagggtctgatgatccgtcgc
tggcaggaacgtggcgtaaaggtggtgattgacaccagtgatgtgaccaccgccgctgga
gctaaaaagctgctggagaatagtaacaagctggctttggtcggaggcatcttcaacctg
gcggctgttctccgcgatgctctgatcgaggatcagaccgccaaggacttcaagacagtg
gctgatcccaaggtgacggccaccaagtacctggatcagttctctcgcgatatctgcact
gagctggactacttcatctgcttctccagtgtttcctgcggtcgtggtaacattggtcag
accaactacggattggccaactctgcaatggagcgaatttgcgagcagcgccaggtgagc
ggattcccaggcaccgccatccaatggggagccatcggagacaccggtctggtgctggag
aacttgggtgacaatgacaccgtgattggaggaaccctgccccagaggatgccctcttgc
ctgcagaccatcgacctgttcctgcaacagccccatccggttgttgcctccatggttgtg
gccgagaagcgcaagtcggatcagtcggctggagtcagcctaattgccaccattgccaac
atccttggtctccgggacaccaagaatatccaggacggagcatcgcttgctgatctcgga
atggactccctgatgagcgctgagatcaaacagactttggagcgaaactttgacattgtt
ctgtccgcccaggagatccgtcagctcacctttggagccctcaaggccatggatggtggt
gctgatgtcaagccagccgcagctgctcccgcagccgctgctggagtcccagaggcaaac
attacctctggtggatcctcgcgcacagctagtcccatgggcgatggaacgcaggtggtg
ttcaccacgtccctcatccccaccgaggcaattgtacaactggacacaaaggcacctgca
aacagcaaacagagccccatcttcttcatttccccgatcgaggggttcgcctccgcactg
gagccgctggccaagcgattggaggtgcccgcctatggactgcagtacacggaagccgtg
ccctccgattctctggaatcagcagccaaattcttcatcaagcagctgcgcaccgtccag
ccaaagggtccctacaaactagccggatactccttcggttgcctgctcacctacgtgatg
gccggtattctggaagagaccaacgaggtggccaatgtgatcatgctggacggagcccca
agctacgtcaactggtacacgagcagcttcaagcagcgttacactgacggcaccaacgcc
gataacgacaaccagagctacggcttggcctactttggaatcgtgttggccaacattgac
tacaaagcgctggtgcgtctgctaatagtgatccccacatgggaggagaaactcgagagg
ttcgctgagctgatgagcaatgagatcacccagcccgtggaaacgatcaagaaatccgcc
actctgttctacaagaaactggagctggccgatggctaccagcccactctgaagctcaag
acgaatgtgaccttggtcaagcccacagacaactctgccaagctggacgaggactatcgc
cttaaggaggtctgcacaaagcccgtggaagtacacactgttgagggcaaccaccgcacc
ttcctcatcgaggatcagtccctgaagaccatccagagcatactgaagcgtctgttcaac
taa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (5)   
   KEGG PATHWAY (3)   
   KEGG MODULE (2)   
Chemical substance (44)   
   KEGG COMPOUND (44)   
Chemical reaction (35)   
   KEGG ENZYME (1)   
   KEGG REACTION (34)   
Genome (1)   
   KEGG GENOME (1)   
Gene (40)   
   KEGG ORTHOLOGY (1)   
   RefGene (35)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (14)   
   Pfam (14)   
All databases (148)   

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