KEGG   Drosophila melanogaster (fruit fly): Dmel_CG9761
Entry
Dmel_CG9761       CDS       T00030                                 
Symbol
Nep2
Name
(RefSeq) neprilysin 2, isoform B
  KO
K08635  neprilysin [EC:3.4.24.11]
Organism
dme  Drosophila melanogaster (fruit fly)
Brite
KEGG Orthology (KO) [BR:dme00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:dme01002]
    Dmel_CG9761 (Nep2)
Enzymes [BR:dme01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.11  neprilysin
     Dmel_CG9761 (Nep2)
Peptidases and inhibitors [BR:dme01002]
 Metallo peptidases
  Family M13: neprilysin family
   Dmel_CG9761 (Nep2)
SSDB
Motif
Pfam: Peptidase_M13_N Peptidase_M13 DUF3461
Other DBs
NCBI-GeneID: 40588
NCBI-ProteinID: NP_001246914
FlyBase: FBgn0027570
UniProt: A0A0B4K692
Position
3R
AA seq 774 aa
MQTVIQNPNWWRRRNKLEKSLLVSLGIMFVVLATGFGLWIGKVLRTSPPSNPQATALHGD
STTINQVPTGTASKGKSGDSGDVCLTQECIHTASTVLRKMKPEVEPCDNFYEFACGTYLE
EENIPDDKVSISTFSVISDKLQEQLKDIITAERPETEPKHFRLPNLLYKACMNKTLIETL
GPEPITRVAERLGGWPLIKGDSWNADDSWTWQEQVKKFRTAGFSMDYIIDFSIGVDLQNS
TKRLIDLDQSSLALSREYLVKGFNETLVTAYYKYMVDIAVLFGANRDLAKTELLLSLEFE
MALANISWPNEKRRNSSELYNLRTPAQLQAAYPYVQWVDYMNALLPEGLNVAEDEMINLS
VPSFFEDLGKLLAKTPKRVIANYMFWRIHGFSVGFLSEEFRKRQLQYATALSGRQEQEAR
WKECVDIATSSMDEVCEDDFDSLGISVGSLYVGKHFHKDSKANALEMVNEIRNVFNDILD
EVNWMDAKTKKEAKLKLHSMATHIGYPDEMLDNEKLAAYYAKLDIDPDKYFESFLGMNIF
GTDYSFNKLRLPVNKTDWVRHARPAIVNAFYSSLENSIQFPAGILQGHFFNAQRPKYMNF
GAIGYVIGHEITHGFDDQGRQFDVKGNLRDWWHPDTQKAYLAKAKCIIEQYGNYTERATG
LNLNGINTQGENIADNGGVKESYIAYRRWAEKHGPEAKLPGLDYTPEQMFWVAAGQTWCA
KYRKESLKMRITTGVHSPSEFRVLGSLSNMKDFAKDFHCPEGSPMNPVQKCEVW
NT seq 2325 nt   +upstreamnt  +downstreamnt
atgcagacggtaatccaaaaccccaactggtggcgtcgccgtaacaaattggaaaaaagt
ctgctggtctcgctgggcatcatgttcgtggtgcttgctaccgggttcggtctctggatt
ggcaaagtgctgaggacgagtcccccgtcgaatccccaggccactgctctccacggcgac
agcaccaccatcaaccaggttccaacgggcaccgcctcgaagggcaagtcgggcgattcg
ggcgacgtgtgcctcacccaggagtgcatccacacggcttccaccgttttgcggaagatg
aagcccgaggtagagccgtgcgacaacttttacgagttcgcctgcggcacataccttgag
gaggagaacatccccgacgacaaggtctccatcagcaccttctccgtgatctccgacaag
ctgcaggagcagttgaaggacatcatcaccgcggagcgaccggaaacggagccgaagcac
ttccgactgcccaacctgctttacaaggcctgcatgaacaaaactctgatcgagaccctg
ggccctgagcccataactcgcgtggccgagaggctgggcggctggccgctgatcaaggga
gactcttggaacgcggacgacagctggacttggcaggagcaggtcaagaagttccgcacc
gccggttttagcatggactacatcatcgacttttcaatcggagtggatttgcagaacagc
actaagcggcttatagatctggaccagtcctccctggccttgagtcgcgagtacctcgtg
aaaggattcaatgagacgctggtgacggcatactacaagtatatggttgacatcgcggtt
cttttcggagcaaatagggacttggccaagacggagctgctgttatctttggagttcgag
atggcgctggccaatatctcctggcccaacgagaagcgacgcaactcctctgagctgtac
aatctaagaactccagcgcagctccaggccgcctacccctacgtgcagtgggtggactac
atgaacgccctgctgccggagggactgaacgtggccgaggacgagatgatcaacctgtcg
gtgcccagcttcttcgaggaccttggcaagctgctggccaagacgccgaagcgtgtcatc
gccaactatatgttctggcgtatccacggcttctccgtgggatttctgagtgaggagttc
cgcaagcgacagctgcagtacgccacagccctttcggggcgccaggaacaggaggctaga
tggaaggagtgcgtcgacatcgccaccagcagcatggatgaagtatgcgaagatgatttc
gatagtcttggcatttccgtgggatcgctctacgtgggcaagcacttccacaaggattcg
aaggccaacgccctggagatggtcaacgaaatccgcaacgtgttcaacgacatcctggac
gaggtcaactggatggacgccaagacgaagaaggaggccaagctaaagctgcacagcatg
gccacccacatcggctatccggacgagatgctcgacaacgagaagctggccgcctactac
gccaagctcgacatcgatcccgacaagtacttcgagtcgttcctgggcatgaacatattt
ggcacggattactcgttcaacaagcttcgtttgccggtcaacaagacggactgggttcgc
cacgctcgtccggcgatcgtgaacgcgttctactcgtccttagagaacagtattcaattc
ccggccggcatcctgcaggggcacttcttcaacgcccaacgtccgaagtacatgaacttt
ggcgccattggctacgtgattggtcacgagatcacccatggtttcgacgaccagggtcgc
cagttcgacgtgaagggcaacctgcgggactggtggcacccggacacccagaaggcctat
ctggccaaggcgaagtgcatcattgagcagtacggcaactacaccgaaagggccacggga
ttgaacttgaatggcatcaacacccagggggagaatatcgccgacaatggtggcgtcaag
gagtcatacatcgcctaccgcagatgggctgagaagcacggaccggaagcaaagcttccg
ggattggactacaccccggagcagatgttctgggtggcagccggacagacttggtgtgct
aagtaccgaaaagaatctctcaagatgcgtattactaccggcgtgcattctccatccgag
ttccgagtcctcgggtcgctcagcaacatgaaggacttcgccaaggacttccattgtcca
gagggatcacccatgaatccggtccaaaagtgcgaggtttggtag

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Ontology (3)   
   KEGG BRITE (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (61)   
   KEGG ORTHOLOGY (1)   
   RefGene (56)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (3)   
   Pfam (3)   
All databases (77)   

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