KEGG   Drosophila melanogaster (fruit fly): Dmel_CG8983
Entry
Dmel_CG8983       CDS       T00030                                 
Symbol
ERp60
Name
(RefSeq) endoplasmic reticulum p60
  KO
K08056  protein disulfide-isomerase A3 [EC:5.3.4.1]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme04141  Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:dme00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    Dmel_CG8983 (ERp60)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:dme03110]
    Dmel_CG8983 (ERp60)
   04131 Membrane trafficking [BR:dme04131]
    Dmel_CG8983 (ERp60)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dme04147]
    Dmel_CG8983 (ERp60)
Enzymes [BR:dme01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.4  Transposing S-S bonds
    5.3.4.1  protein disulfide-isomerase
     Dmel_CG8983 (ERp60)
Chaperones and folding catalysts [BR:dme03110]
 Protein folding catalysts
  Protein disulfide isomerase
   Dmel_CG8983 (ERp60)
Membrane trafficking [BR:dme04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   PDI family proteins
    Dmel_CG8983 (ERp60)
Exosome [BR:dme04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   Dmel_CG8983 (ERp60)
  Exosomal proteins of colorectal cancer cells
   Dmel_CG8983 (ERp60)
  Exosomal proteins of bladder cancer cells
   Dmel_CG8983 (ERp60)
SSDB
Motif
Pfam: Thioredoxin Thioredoxin_6 Thioredoxin_2 Thioredoxin_7 Thioredoxin_8 AhpC-TSA Redoxin TraF OST3_OST6 Thioredoxin_9
Other DBs
NCBI-GeneID: 36270
NCBI-ProteinID: NP_725084
FlyBase: FBgn0033663
UniProt: Q3YMU0
Position
2R
AA seq 489 aa
MMWRLAGVLLLGFIAISSGAEQDVLELGDDDFATTLKQHETTLVMFYAPWCGHCKRLKPE
YAKAAEIVKDDDPPIKLAKVDCTEAGKETCSKYSVSGYPTLKIFRQDEVSQDYNGPREAS
GIAKYMRAQVGPASKTVRTVAELKKFLDTKDTTLFGYFSDSDSKLAKIFLKFADKNREKY
RFGHSSEKEVLDKQGETDKIVLIRAPHLSNKFESSSIKFEGSSESDLSTFVKENFHGLVG
HRTQDSVKDFQNPLITAYYSVDYQKNPKGTNYWRNRVLKVAKEFVGQINFAIASKDDFQH
ELNEYGYDFVGDKPVVLARDEKNLKYALKDEFSVENLQDFVEKLLANELEPYIKSEPIPE
SNDAPVKVAVAKNFDDLVINNGKDTLIEFYAPWCGHCKKLSPIYEELAEKLQDEDVAIVK
MDATANDVPPEFNVRGFPTLFWLPKDAKNKPVSYNGGREVDDFLKYIAKEATTELKGFDR
SGKPKKTEL
NT seq 1470 nt   +upstreamnt  +downstreamnt
atgatgtggcgccttgctggagtgctcctactaggcttcatcgccatctcgtccggagcg
gagcaggatgtcctggaactgggggacgacgactttgccaccaccctaaaacaacacgag
acgacgctggtcatgttctacgccccctggtgcggccactgcaagcgattgaagcccgag
tacgccaaggcggcggagatcgtgaaagacgatgatccgccaatcaaactggccaaggtt
gactgtacggaagctggaaaggaaacgtgtagcaagtactccgtcagcggctacccaacg
ttgaagattttccgtcaggatgaggtgtcgcaggactacaatggaccacgcgaagccagc
ggcattgccaagtacatgcgcgcccaagtgggacccgcctccaagaccgtgcgcaccgtt
gccgagctgaaaaagttcctggacaccaaggacaccacgctgttcggctacttcagcgac
agcgactccaaactggccaagattttcctgaagttcgccgataagaaccgcgaaaagtac
cgcttcggacattcaagcgaaaaggaagtcctcgataagcagggcgaaaccgacaagatt
gtgcttattcgtgccccccatctgagcaacaagttcgagtcatcttccattaagttcgag
ggtagctccgagtccgatctgtctacctttgtcaaggagaacttccatggtcttgtggga
caccgcactcaggattcggtcaaggatttccagaatcctttgatcactgcctactacagc
gtggactaccagaagaaccccaagggaacgaactactggcgcaaccgtgtgctcaaggtg
gccaaggagtttgtgggtcaaatcaactttgcgatcgcctccaaggatgacttccagcac
gagttgaacgagtacggctacgatttcgttggcgacaagccagtggtattggctcgcgac
gaaaagaatctcaaatacgccctgaaggacgagttctcagtggagaatctgcaggacttt
gtcgagaagctgctggcgaatgagctggagccgtacattaagagtgagcctattcccgag
tcgaacgacgctcccgtcaaggtggccgtcgccaagaacttcgacgatctggttatcaac
aatggcaaagacacgctgattgagttctacgccccatggtgcggccactgcaagaagctg
agtcccatctacgaggagctggccgagaagctgcaagacgaagatgtggccatcgtcaag
atggacgccaccgccaacgatgtgccgccggagttcaacgtgcgcggcttccccaccctc
ttctggctgcccaaggacgccaagaacaagccagtcagctacaacggaggtcgcgaggta
gacgacttccttaagtacatcgccaaggaggcgaccacagaactgaagggcttcgaccgc
agcggcaagcccaagaagaccgagctctaa

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (380)   
   KEGG ORTHOLOGY (1)   
   RefGene (375)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (401)   

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