KEGG   Drosophila melanogaster (fruit fly): Dmel_CG6988
Entry
Dmel_CG6988       CDS       T00030                                 
Symbol
Pdi
Name
(RefSeq) protein disulfide isomerase, isoform E
  KO
K09580  protein disulfide-isomerase A1 [EC:5.3.4.1]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme04141  Protein processing in endoplasmic reticulum
Brite
KEGG Orthology (KO) [BR:dme00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    Dmel_CG6988 (Pdi)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:dme03110]
    Dmel_CG6988 (Pdi)
   04131 Membrane trafficking [BR:dme04131]
    Dmel_CG6988 (Pdi)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dme04147]
    Dmel_CG6988 (Pdi)
Enzymes [BR:dme01000]
 5. Isomerases
  5.3  Intramolecular oxidoreductases
   5.3.4  Transposing S-S bonds
    5.3.4.1  protein disulfide-isomerase
     Dmel_CG6988 (Pdi)
Chaperones and folding catalysts [BR:dme03110]
 Protein folding catalysts
  Protein disulfide isomerase
   Dmel_CG6988 (Pdi)
Membrane trafficking [BR:dme04131]
 Endoplasmic reticulum (ER) - Golgi transport
  Forward pathways
   PDI family proteins
    Dmel_CG6988 (Pdi)
Exosome [BR:dme04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   Dmel_CG6988 (Pdi)
  Exosomal proteins of colorectal cancer cells
   Dmel_CG6988 (Pdi)
  Exosomal proteins of bladder cancer cells
   Dmel_CG6988 (Pdi)
SSDB
Motif
Pfam: Thioredoxin Thioredoxin_6 Thioredoxin_8 Thioredoxin_2 Thioredoxin_7 OST3_OST6 AhpC-TSA Redoxin TraF Thioredoxin_4 Sep15_SelM iSTAND
Other DBs
NCBI-GeneID: 39651
NCBI-ProteinID: NP_001287070
FlyBase: FBgn0286818
UniProt: P54399 X2JGP4
Position
3L
AA seq 496 aa
MKFLICALFLAASYVAASAEAEVKVEEGVLVATVDNFKQLIADNEFVLVEFYAPWCGHCK
ALAPEYAKAAQQLAEKESPIKLAKVDATVEGELAEQYAVRGYPTLKFFRSGSPVEYSGGR
QAADIIAWVTKKTGPPAKDLTSVADAEQFLKDNEIAIIGFFKDLESEEAKTFTKVANALD
SFVFGVSSNADVIAKYEAKDNGVVLFKPFDDKKSVFEGELNEENLKKFAQVQSLPLIVDF
NHESASKIFGGSIKSHLLFFVSREGGHIEKYVDPLKEIAKKYRDDILFVTISSDEEDHTR
IFEFFGMNKEEVPTIRLIKLEEDMAKYKPESDDLSAETIEAFLKKFLDGKLKQHLLSQEL
PEDWDKNPVKVLVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDI
VIAKMDSTANELESIKISSFPTIKYFRKEDNKVIDFNLDRTLDDFVKFLDANGEVADSEP
VEETEEEEEAPKKDEL
NT seq 1491 nt   +upstreamnt  +downstreamnt
atgaaattcctgatctgtgcacttttcttggcggcgtcctacgtggccgcttccgccgag
gcggaggtcaaagttgaggagggtgttctggtggcgacggtggacaacttcaagcagctg
attgccgacaacgagttcgtgctggtcgagttctacgccccatggtgcggacactgcaaa
gctctggctcccgagtacgccaaggctgcccagcaactggccgagaaggagtcgcccatc
aagctggccaaggtcgatgccaccgtcgagggtgagctggccgagcagtacgccgtccgt
ggctaccccactctgaagttcttccgcagcggctctccagtggagtacagcggtggccgc
caggccgctgacatcattgcctgggtgaccaagaagaccggcccaccagccaaggatctg
accagcgtcgctgatgccgagcaattccttaaggacaacgagatcgccatcattggattc
ttcaaggacctggaatcggaggaggccaagaccttcaccaaagtcgccaacgccctggac
tcgttcgtctttggtgtgagcagcaatgccgatgtgattgccaagtacgaggctaaggac
aatggagtggttctgttcaagcccttcgacgacaagaagtccgtgttcgagggtgagctg
aacgaggaaaacctgaagaagttcgcccaggtgcagtctctgcccctgatcgttgacttc
aaccacgaatctgcttccaagatcttcggtggctcgatcaagtcgcatctgctgttcttc
gtgtccagggagggcggccacatcgagaagtacgtcgatcccctgaaggagatcgccaag
aagtaccgcgacgacatcctgttcgtgaccatctcgtccgacgaggaggaccatacccgc
atcttcgagttcttcggcatgaacaaggaggaggtgcccaccatccgtctgatcaagctg
gaagaggacatggccaagtacaagcccgaatcggacgatctgtccgccgagaccatcgag
gcgttccttaagaagttcctggacggcaagctgaagcaacacctcctttcccaggagctg
cccgaggattgggacaagaaccccgtcaaggtgctggtatccagcaacttcgagagcgtt
gccctggacaagagcaagagcgtgctggttgagttctacgccccatggtgcggacactgc
aagcagctggcccccatctacgaccagctggctgagaagtacaaggacaatgaggatatt
gtcattgccaagatggactccactgccaacgagctggagagcattaagatctcgtccttc
cccacaatcaaatacttccgcaaggaggacaacaaggtcatcgacttcaacctggacagg
actctcgatgatttcgtcaagttcctcgatgccaacggtgaggtggccgattccgagccc
gtcgaggagaccgaggaggaggaggaggcgcccaagaaggacgagttgtaa

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (153)   
   KEGG ORTHOLOGY (1)   
   RefGene (148)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (12)   
   Pfam (12)   
All databases (180)   

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