KEGG   Drosophila melanogaster (fruit fly): Dmel_CG10489
Entry
Dmel_CG10489      CDS       T00030                                 
Symbol
PolE2
Name
(RefSeq) DNA polymerase epsilon subunit 2
  KO
K02325  DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme03030  DNA replication
dme03410  Base excision repair
dme03420  Nucleotide excision repair
Brite
KEGG Orthology (KO) [BR:dme00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    Dmel_CG10489 (PolE2)
   03410 Base excision repair
    Dmel_CG10489 (PolE2)
   03420 Nucleotide excision repair
    Dmel_CG10489 (PolE2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:dme03032]
    Dmel_CG10489 (PolE2)
   03400 DNA repair and recombination proteins [BR:dme03400]
    Dmel_CG10489 (PolE2)
Enzymes [BR:dme01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.7  Nucleotidyltransferases
    2.7.7.7  DNA-directed DNA polymerase
     Dmel_CG10489 (PolE2)
DNA replication proteins [BR:dme03032]
 Eukaryotic type
  DNA Replication Elongation Factors
   DNA polymerase epsilon complex
    Dmel_CG10489 (PolE2)
DNA repair and recombination proteins [BR:dme03400]
 Eukaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    Long Patch-BER factors
     DNA polymerase epsilon complex
      Dmel_CG10489 (PolE2)
SSDB
Motif
Pfam: DNA_pol_E_B Dpoe2NT
Other DBs
NCBI-GeneID: 38661
NCBI-ProteinID: NP_647995
FlyBase: FBgn0035644
UniProt: Q9VRQ7
Position
3L
AA seq 525 aa
MDVDLLPLRKRITNTFKLCGFLIRSENSSYLAEQLLPFDAAERDKWLTVITENLQSQKLL
TPHVERAALEKAINELNRVGLDEGETVFALIDAFTVPRFRYNQRIKKFELDTQPRQLLTA
PRMKSDYMQQRYAMLLQKTLRHDLFAPAVIQDGVGAEAQAKKFKLQFAENLLATSAMKEA
VVLGLLTQLKEGKFYVEDPTGCVQLDLTGARFHAGFFCEGCFVLAEGNYNNGVLKVDGLG
FPPAEPANSSRAFFGTANTWGGESAKLLKYSAGLQELERTNTETTIVFLSDVRLDLPVVM
EKLRQLFVGYDSCPPQAIVLMGPFTASTRNHHELRHHLDALGGLAAGCEQLKKQTDLILV
PSSEDPTAPNILPRAPIPECLAAGLLKAWPRTQLATNPCRLQYCTQQIVVCRLDLMAKFC
RNTLHFPEDTSQIEQHFARTIVCQGHLVPIHPIAMPVHWDYDPALWLYPLPDLIVMGDSC
QSFSSSQHGCTVLNTGSFVKSKFAFKVYIPATRTIEDSEIPDELE
NT seq 1578 nt   +upstreamnt  +downstreamnt
atggatgtggatttactgccgctgagaaagcgaataacaaacaccttcaagctatgtgga
ttcctgatccgctcggagaacagttcctacctggcggagcagctgctaccctttgacgca
gcggaacgggacaaatggctgacggtgatcaccgagaatctccaaagccaaaagcttttg
acgcctcatgtggagcgagccgccctggagaaggccatcaatgaacttaaccgggtggga
ttggatgaaggggagacggtctttgccctgatcgatgcctttacggtgccccgttttcgg
tacaaccagcggataaagaaattcgaactggacactcagccgcgccagttgctgaccgcc
ccgcgcatgaaatcggactacatgcagcaacgatatgccatgttactacagaaaactctg
cgacacgatctctttgccccagccgtcatacaggatggcgttggggccgaggcccaggcc
aagaaatttaagctccagttcgcggagaacctgctggccacgtcggcgatgaaggaggca
gttgttttggggctacttacccagcttaaagagggcaagttctatgtcgaggatcccacg
ggttgcgtccagttagatctcactggagcccgtttccatgccggcttcttctgcgagggc
tgctttgttttagccgagggcaactataacaacggtgtgctcaaggttgatggcctgggc
tttccacctgcggaaccggcaaacagcagtcgagcatttttcggcaccgccaacacttgg
ggcggtgaatctgctaagctgctgaagtactcagccggactacaggaactggagcgtacc
aacacggaaacaaccattgttttcctttccgacgttcggttggatctgccggttgtcatg
gagaagctgcgccagttgttcgtgggctatgattcctgtccgccgcaggctatagtgctc
atgggtcccttcacggccagcacaaggaatcatcatgaactgaggcatcacctggatgca
ttgggtggcttggcagctggctgcgagcagctgaagaagcaaacggatctgatactcgtt
ccctcgtccgaagatcccacggcacctaatattctgccccgtgctccaattcccgaatgc
ctggcagccgggctgctaaaggcctggccacgcacccagttggctacgaatccgtgtcgc
ctgcagtactgcacccagcagattgtggtctgccgtctggatttgatggccaagttttgt
cgcaacaccttgcattttcctgaagacacgtcccagatcgagcagcattttgccagaacg
attgtgtgccagggtcatttggtgcccattcatccgattgccatgccagtgcactgggac
tacgatcctgctctgtggttgtatccactgccggatctgattgtcatgggcgattcgtgt
cagagctttagcagcagtcaacatggctgcactgttctcaataccggctcctttgtcaag
tccaagttcgcattcaaagtgtatataccagcgacgcgaacgattgaggactcggagata
ccggacgaattggagtag

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