KEGG   Drosophila melanogaster (fruit fly): Dmel_CG10118
Entry
Dmel_CG10118      CDS       T00030                                 
Symbol
ple
Name
(RefSeq) pale, isoform C
  KO
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Organism
dme  Drosophila melanogaster (fruit fly)
Pathway
dme00350  Tyrosine metabolism
dme00790  Folate biosynthesis
dme01100  Metabolic pathways
Brite
KEGG Orthology (KO) [BR:dme00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    Dmel_CG10118 (ple)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    Dmel_CG10118 (ple)
Enzymes [BR:dme01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2  tyrosine 3-monooxygenase
     Dmel_CG10118 (ple)
SSDB
Motif
Pfam: Biopterin_H TH_ACT
Other DBs
NCBI-GeneID: 38746
NCBI-ProteinID: NP_001286955
FlyBase: FBgn0005626
UniProt: P18459 B5X0J4
Position
3L
AA seq 579 aa
MMAVAAAQKNREMFAIKKSYSIENGYPSRRRSLVDDARFETLVVKQTKQTVLEEARSKAN
DDSLEDCIVQAQEHIPSEQDVELQDEHANLENLPLEEYVPVEEDVEFESVEQEQSESQSQ
EPEGNQQPTKNDYGLTEDEILLANAASESSDAEAAMQSAALVVRLKEGISSLGRILKAIE
TFHGTVQHVESRQSRVEGVDHDVLIKLDMTRGNLLQLIRSLRQSGSFSSMNLMADNNLNV
KAPWFPKHASELDNCNHLMTKYEPDLDMNHPGFADKVYRQRRKEIAEIAFAYKYGDPIPF
IDYSDVEVKTWRSVFKTVQDLAPKHACAEYRAAFQKLQDEQIFVETRLPQLQEMSDFLRK
NTGFSLRPAAGLLTARDFLASLAFRIFQSTQYVRHVNSPYHTPEPDSIHELLGHMPLLAD
PSFAQFSQEIGLASLGASDEEIEKLSTVYWFTVEFGLCKEHGQIKAYGAGLLSSYGELLH
AISDKCEHRAFEPASTAVQPYQDQEYQPIYYVAESFEDAKDKFRRWVSTMSRPFEVRFNP
HTERVEVLDSVDKLETLVHQMNTEILHLTNAISKLRRPF
NT seq 1740 nt   +upstreamnt  +downstreamnt
atgatggccgttgcagcagcccaaaagaaccgcgagatgttcgccatcaagaaatcctac
agtattgagaatggctatccatcccgccgtcgcagcctggtggatgatgcccgtttcgag
accctggtggtcaagcagaccaaacaaaccgtcctcgaggaggcccgcagcaaggcaaat
gacgattccctggaagattgcattgtgcaggctcaggagcacattccctccgagcaagat
gtggagctccaggacgagcatgccaatctggagaacctgcccttggaggaatatgttcca
gttgaggaggatgttgagtttgagagcgttgaacaggagcagtcggagtcgcagtcgcag
gagccagaaggcaaccaacagccgaccaagaacgattacggtctcaccgaggacgagatt
ttgttggccaatgccgcctccgaatcctcggatgccgaggctgccatgcagagtgccgct
ttggtggtccgcctcaaggagggcatctcctccttgggtcgcatcctcaaggccatcgaa
accttccacggcaccgtccagcatgtggagtcccgtcagtcgcgcgtggagggcgtggac
cacgatgtcctcatcaagttggacatgacccgtggcaatctgctgcagctgatccgctcc
ctcaggcagtcgggctccttcagcagcatgaatctgatggccgacaataacttgaatgtc
aaggctccgtggttccccaagcacgcctccgaattggataactgcaaccatctgatgacc
aagtacgagcccgatttggacatgaaccaccccggattcgccgacaaggtataccgccag
cgtcgcaaggaaattgccgagatcgcattcgcctacaagtacggagacccgatcccattc
atcgactactccgatgtggaggtcaagacctggcgctcggtgttcaagaccgttcaggat
ctggctcccaagcacgcctgtgccgagtaccgggccgccttccagaagctccaggatgag
cagatcttcgtggagacccgtctgccccagttgcaggagatgtccgactttctgcgcaag
aacaccggattctctctccgtcctgccgccggtcttttgactgcccgggacttccttgcc
tccttggccttccgcatcttccagagcacccagtatgtgcgccacgttaactcaccatac
cacacccccgagcccgactccattcacgagctgctgggtcacatgcccctgctggccgat
cccagcttcgcccagttctcgcaggagattggactggcctcgctgggtgcctccgacgaa
gaaatcgagaagctgtccacggtatactggttcactgttgagttcggtctctgcaaggaa
catggtcagatcaaggcctacggtgctggactcctgagctcctacggtgagctgctccat
gccatcagcgacaagtgcgagcaccgcgccttcgagcccgcatccaccgccgtgcagccc
taccaggatcaggagtaccagcccatctactatgtggccgagagcttcgaggatgccaag
gacaagttccgtcgctgggtgagcaccatgtcgcgtccattcgaggtgcgtttcaacccg
cacaccgagcgcgtcgaggtgctggactccgtcgacaagctggagactctggtgcaccag
atgaacacggagattttgcatctgaccaacgccatctccaagttgcgacgcccgttctaa

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (7)   
   KEGG COMPOUND (7)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (12)   
   KEGG ORTHOLOGY (1)   
   RefGene (7)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (6)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (3)   
   RefSeq(nuc) (3)   
Protein domain (2)   
   Pfam (2)   
All databases (40)   

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