KEGG   Danio rerio (zebrafish): 100003877
Entry
100003877         CDS       T01004                                 
Symbol
lrp6
Name
(RefSeq) low-density lipoprotein receptor-related protein 6 precursor
  KO
K03068  low density lipoprotein receptor-related protein 5/6
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04150  mTOR signaling pathway
dre04310  Wnt signaling pathway
Brite
KEGG Orthology (KO) [BR:dre00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    100003877 (lrp6)
   04150 mTOR signaling pathway
    100003877 (lrp6)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:dre04131]
    100003877 (lrp6)
Membrane trafficking [BR:dre04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Low-density lipoprotein receptor (LDLR) family proteins
    100003877 (lrp6)
SSDB
Motif
Pfam: Ldl_recept_b FXa_inhibition Ldl_recept_a SGL DUF5050 Insulin_TMD cEGF
Other DBs
NCBI-GeneID: 100003877
NCBI-ProteinID: NP_001128156
ZFIN: ZDB-GENE-090821-1
UniProt: B5L5I6
Position
4:74609..100007
AA seq 1620 aa
MGAVLQTLLLCTLCLQIRGLPLLLYANRRDLRLVDAAHGRANATLVMGGLEDAAAVDYIY
AQGLIYWSDVSEESIKRTLFNGSAPSGVQTTVISGLASPDGLACDWMGNKLYWTDSETNR
IEVAELDGTHRKVLFWQDLDQPRAIALDPGRGFMYWTDWGEIPKIERAGMDGSLRSVIVE
TEIYWPNGLTLDYQQQQLYWADAKFNCIHRSNLDGSSREVVVKGSLPHPFALTLYEDTLF
WTDWNTHSIHSCHKHTGENSREVHSNIFSPMDIHVYSQQRQPMDVASPCSVRNGGCSHLC
LLSPAKPYYQCACPTGVQLLEDHKSCRDGGPSQLLLLARRTDLRRISLDTPDFTDIVLQA
EDIRHAIAIDYDPVEGHIYWTDDEVRAIRRSLLDGSDAQLVVTSQVNHPDGIAVDWIARN
LYWTDTGTDRIEVTRLNGTMRKILISEDLDEPRAIVLDPVAGYMYWTDWGEVPKIERAAL
DGSQRMVMVNTSLGWPNGLALDYSERKIYWGDAKTDVIEVMEMDGSGRRVLLEDNLPHVF
GFTLLGDYIYWTDWQRRSIERVHKRSTEREVIIDQLPDLMGIKATFVHQTFGVNPCAWAN
GGCSHLCLYRPQGVSCACPIGLELMADLSTCIVPEAFLLFSRHTDIRRISLETNNNNVAI
PLTGVKEASALDFDITDNRIYWTDITLKTISRAFMNGSSLEHVVEFGLDYPEGMAVDWLG
KNLYWADTGTNRIEVAKLDGQHRQVLVWKDLDSPRALALDPAEGFMYWTEWGGRPKIDRA
AMDGSGRITLVPNVGRANGLTIDYAERRLYWTDLDTTLIESSNMLGLEREVIADDLPHPF
GLTQYQDYIYWTDWSQRSIERANKTSGQNRTVIQGHLDYVMDILVFHSSRQSGWNACAAT
NGHCSHLCLAVPVCSFTCGCPAHYSLNTDNKTCSAPTSFLLFSQKTAINRMVMDELQSPD
IILPIHSLRNVRAIDYDPLDRHLYWIDAKQNVIRRAQEDGNQSVTVVSGAVGGSNLGLQP
YDLSIDIYSRFIYWTSELTNVINVTRTDGSRVGVVLRGEHDKPRAIAVNPERGYMYFSNL
QERSPKIERCALDGTEREVLFFSNLGRPVALAVDNELGKLFWVDMDLRRIESSDLSGANR
IVIEDSNILQPVGLTVFGNFLYWIDRQQQMIERIHKVTREGRTKIQARIASLSDIHAVHQ
LDMQEYSKHPCTSDNGGCTHICIVKGDGTTRCSCPIHLVLLQDELSCGEPPTCSPEQFSC
VSGEVDCIPQAWRCDGFAECDDSSDERDCPVCSSREFQCDSRQCVDAALRCNGEINCQDR
SDENKCEVLCPADQFTCSNGQCIGRHKKCDNNMDCTDNSDEIGCYATEEPSFAPTNTIGS
IVGVVMVLFVVGAVYFVCQRVLCPQMKDDADTMTNDFVVHGPPPVPLGYVPHPASLSGSL
PGMSRGKSVMGSLSIMGGSSGPPYDRAHVTGASSSSSSSTKGAYFPPILNPPPSPATVRS
QYTMEFGYSSNSPSTHRSYSYRPYSYRHFAPPTTPCSTDVCDSDYTPGRRAPHASSATAA
KGYASDLNYDSEPLPPPPTPRSQYLSAEENCESCPPSPYTERSYSHQLYPPPPSPCTDSS
NT seq 4863 nt   +upstreamnt  +downstreamnt
atgggtgccgtgcttcagactctcttactgtgtactttgtgtttgcagatacgcgggctg
ccgctgctcctgtatgctaaccggagggacctgcgtctggtggacgcggctcacggtcgg
gccaacgccacgctggtgatgggcggtctggaggacgcggcggcggtggattatatctat
gcgcagggcctgatctactggagcgacgtgagcgaggagtctattaaacggacgctgttt
aacggctcggcgcccagcggcgttcagaccaccgtcatctccggtctggcctctccggat
ggcctggcctgcgattggatggggaataaactttactggaccgactccgagaccaaccgc
atcgaggtggcagagctggacgggacgcaccgcaaggtgttattctggcaggacctggac
cagccgagggccatcgctctggacccgggccgcgggttcatgtactggacggactggggc
gagatcccgaagatcgagcgtgctgggatggacgggtcgctgcgctctgtcatcgtggaa
acggagatctactggcccaacggcctgaccctcgactaccagcagcagcagctctactgg
gccgacgccaagttcaactgcatacaccgctccaacctggacggctccagcagggaggtg
gtggtgaagggctctctgccgcacccgtttgcgctgacgctgtacgaggacacactcttc
tggacggactggaacacacactccattcactcgtgccacaaacacacgggcgagaacagc
cgcgaggtacactccaacatcttctccccgatggacatccacgtctacagccagcagcgc
cagcccatggacgtggcgagcccctgctctgtgaggaatggaggatgttctcatctgtgt
ttgctgtctccggccaaaccctactatcagtgcgcctgtccaaccggcgtacagctgctg
gaggaccacaagagctgcagagacggtggcccgtctcagctcctcctgctagcgcgccgc
acagacctgcgccggatctctctggacacgccggacttcactgatatcgtgctgcaggcc
gaggacatccggcacgccatcgccatcgactacgacccggtggagggacacatctactgg
acggacgacgaggtgcgcgccatccgcaggtccctcctggacggcagcgacgctcagctg
gtggtgacctcgcaggtgaaccacccggacggcatcgccgtggactggatcgcacgaaac
ctctactggaccgacaccggcacggaccgcatcgaggtgacccgactgaacggcaccatg
aggaagatcctgatctcagaggatctggacgagcccagagccatcgtgctggaccccgtc
gccggatacatgtactggacagactggggcgaggtgccgaagatcgagcgggcggctctg
gacgggtcgcagcggatggtgatggtcaacacttctctgggctggcccaacggcctggcg
ctcgactacagcgagaggaagatctactggggggacgccaagaccgacgtcatcgaggtg
atggagatggacggttcgggccggcgggttctgctggaggataacctgccgcatgtgttc
ggcttcacgctgctgggagactacatctactggacggactggcagcggcgcagcatcgag
cgcgtgcacaagcgcagcaccgagcgggaggtcatcatcgaccagctgcccgacctcatg
ggcatcaaggccacgttcgtccaccagaccttcggggtgaacccgtgtgcgtgggctaat
ggcggctgcagtcacctgtgcctgtaccggcctcagggtgtgtcgtgtgcgtgtcctatc
ggcctggagctgatggcggatctcagcacctgcatcgtccccgaggccttcctgctgttt
tcccgccacaccgacatcagacgcatctccctggagaccaacaacaacaacgtggccatc
ccactgaccggcgtcaaggaggcgtccgccctcgacttcgacatcaccgacaaccgcata
tactggaccgacatcacactgaagacgatcagtcgggccttcatgaacggcagctctctg
gagcatgtggtggagttcgggctggattacccagaaggcatggcggtggactggctgggc
aagaacctgtactgggctgacacgggcaccaaccgcatcgaggtggccaagctggacggg
cagcaccggcaggtgctggtgtggaaggatctggacagcccccgcgcactcgccctcgac
cccgctgaagggttcatgtactggacagagtggggcgggcggcccaagatagaccgtgca
gcgatggacgggtcgggccgcatcactctggtgccgaacgtgggccgagcgaacggactg
accatcgattatgcagagcgacggctctactggaccgacctcgacaccacactcatagag
tcctccaacatgctgggtctggagcgcgaggtgattgcggatgatctcccgcacccgttc
ggcctgacgcagtatcaggactacatctactggacggactggagccagcgcagcatcgag
cgcgccaacaagaccagcgggcagaaccgcaccgtcattcagggccacctggactacgtg
atggacatcctggtgttccactcgtcccggcagagcggctggaacgcctgcgccgccacc
aacggccactgctcacacctgtgcctcgccgtacctgtgtgcagcttcacctgcggctgc
cccgcccactactccctcaacaccgacaacaagacctgcagcgctccgacgtcgttcctg
ctgttcagccagaagacggctattaaccgcatggtgatggacgagctgcagagccccgac
atcatcctgcccatccacagcctgcggaacgtgcgcgccatcgactacgacccgctggac
cggcacctgtactggatcgacgccaagcagaacgtgatccgccgagcacaggaggacggg
aaccagagtgtgacggtggtgtccggcgctgttggcggctcaaacctcggcctgcagccg
tacgacctgagcatcgacatctacagccgcttcatctactggaccagcgagctcaccaac
gtcatcaacgtgacgcgcacagacggctcgcgggtcggcgtggtgctgcgcggagaacac
gacaaaccccgcgccatcgccgtcaaccctgagcgcgggtacatgtacttcagtaatctg
caggagcgctccccgaagatcgagcgctgtgctctggacgggacggagcgtgaggtgctg
ttcttcagtaatctgggccggccggtggctctggctgtggataatgagctgggcaaactc
ttctgggtggacatggacctgcggcgcatcgagagcagcgacctgtccggagccaatcgg
attgtgatcgaggactccaacatcctgcagccggtgggcctgacggtgttcgggaacttc
ctgtactggatcgaccggcagcagcagatgatcgagaggatccacaaggtgacgagagag
ggacgaaccaaaatacaggcgcgcatcgcctcactgagcgacatccacgccgtccaccag
ctggacatgcaggagtacagtaaacacccctgcacgtctgataacggcggctgcacacac
atctgcattgtaaagggagacggaaccacacgctgctcctgccccattcacctggtgctg
ctgcaggacgagctctcgtgcggagagccgcccacgtgttctccagagcagttctcgtgt
gtgtcgggtgaggtggactgtatcccgcaggcgtggcgctgtgacgggtttgcggagtgt
gatgacagcagtgatgagcgggactgtcctgtctgctccagccgggagttccagtgtgac
agccggcagtgtgtggacgcggcgctgcgctgcaacggagagatcaactgccaggaccgc
tccgacgagaacaagtgtgaagttctgtgccctgcggatcagttcacctgctcaaacgga
cagtgcatcggccgacacaagaaatgtgacaacaacatggactgcacagacaactcagac
gagatcggctgctatgcgacagaggagccgtcgtttgctcccactaacaccatcggctca
atcgtgggtgtggtgatggtgctgttcgtggtcggcgcggtgtatttcgtgtgccagcgc
gtgctctgcccgcagatgaaggacgacgccgacaccatgaccaatgacttcgtggttcac
ggaccgccgccggtgccgctgggatacgtcccacaccccgcatccctgagcggatcactg
ccaggcatgtccagagggaagtcagtcatgggctcgctgagcatcatgggaggcagcagt
ggaccaccgtacgaccgcgctcatgtgaccggagcctcgtccagcagctcgtccagcact
aaaggagcatatttccctccgatcctgaaccctcctccatctccagccaccgtcaggtct
cagtacaccatggagttcggctactcctccaacagcccgtcaacacaccgctcctacagc
tatcggccgtacagttaccgccacttcgctcctccgacgacgccgtgcagcacggatgtg
tgcgacagtgactatacgccgggccgccgggctccgcacgcatccagcgccactgctgct
aaaggctacgctagcgacctgaactacgactcggagccgctgccgccgccgcccacgccg
cgcagccagtacctgtcggcggaggagaactgcgagagctgcccgccgtcaccgtacacc
gagcgcagctactcgcaccagctgtacccgccgccgccctcgccctgcacagactcctcc
tga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (49)   
   KEGG ORTHOLOGY (1)   
   RefGene (44)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (7)   
   Pfam (7)   
All databases (66)   

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