KEGG   Danio rerio (zebrafish): 280649
Entry
280649            CDS       T01004                                 
Symbol
plk1
Name
(RefSeq) serine/threonine-protein kinase PLK1
  KO
K06631  polo-like kinase 1 [EC:2.7.11.21]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04068  FoxO signaling pathway
dre04110  Cell cycle
dre04114  Oocyte meiosis
dre04914  Progesterone-mediated oocyte maturation
Brite
KEGG Orthology (KO) [BR:dre00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    280649 (plk1)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    280649 (plk1)
   04114 Oocyte meiosis
    280649 (plk1)
 09150 Organismal Systems
  09152 Endocrine system
   04914 Progesterone-mediated oocyte maturation
    280649 (plk1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:dre01001]
    280649 (plk1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dre03036]
    280649 (plk1)
Enzymes [BR:dre01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.21  polo kinase
     280649 (plk1)
Protein kinases [BR:dre01001]
 Serine/threonine kinases: Other
  PLK family [OT]
   280649 (plk1)
Chromosome and associated proteins [BR:dre03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     280649 (plk1)
  Centrosome formation proteins
   Kinases and associated factors
    280649 (plk1)
  Sister chromatid separation proteins
   Polo kinases
    280649 (plk1)
SSDB
Motif
Pfam: Pkinase POLO_box PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal ABC1 Phage_NinH
Other DBs
NCBI-GeneID: 280649
NCBI-ProteinID: NP_001003890
ZFIN: ZDB-GENE-021115-7
Ensembl: ENSDARG00000058471
UniProt: Q4KMI8
Structure
Position
1:9153187..9161695
AA seq 595 aa
MSAAIAKPSAKPSAHVDPKSAPLKEIPDVLVDPRTMKRYMRGRFLGKGGFAKCYEITDMD
TKEVFAGKVVPKSMLLKPHQKEKMSTEIAIHKSLDNPHVVGFHGFFEDDDFVYVVLEICR
RRSLLELHKRRKAVTEPEARYFMRQTIQGVQYLHNNRVIHRDLKLGNLFLNDDMDVKIGD
FGLATKIEFDGERKKTLCGTPNYIAPEVLCKKGHSFEVDIWSLGCILYTLLVGKPPFETS
CLKETYIRIKKNEYSVPRHINPVASALIRRMLHADPTLRPSVAELLTDEFFTSGYAPMRL
PTSCLTVPPRFSIAPSSLDPALLRKPLSSLNKGTDSPIEEMGKMDQPQREDLQQRDGPEQ
PDTHLTDMLQQLAVVNAAKPSDRDFIRQEEAEDPACIPVFWISKWVDYSDKYGLGYQLSD
NSVGVLFNDSTRLIMCADGDSLQYIDRNSLESYLSVRSYPSALSKKITLLKYFRNYMSEH
LLKAGANITPREGDELTRLPYLRHWFRTKSAIVLHLSNGTVQINFFQDHTKLILCPLMGA
VTYINEKREFYTYKMTLIEEFGCCKELASRLRYARNMVEKLMACKSSTTAATSAR
NT seq 1788 nt   +upstreamnt  +downstreamnt
atgagtgctgcaattgcaaagccatcggcgaagccatcggctcacgtcgatcccaaatct
gctcctctgaaagagattcccgacgttctggtggatccgagaaccatgaagagatacatg
agaggtcgctttttgggaaaaggaggattcgccaaatgctacgaaatcacagatatggac
acaaaagaggttttcgctgggaaagttgtgccgaagtcgatgctgctgaagccgcaccag
aaggagaaaatgagcacagaaatcgccattcacaaaagtctcgataatccgcatgttgtg
ggctttcacgggttctttgaggatgatgacttcgtgtatgtggtgctggaaatctgtcgc
agaaggtctctccttgaattgcacaaaaggaggaaggcagtgactgagcctgaggcccga
tacttcatgcgccagactattcagggtgttcagtacttgcacaacaacagagtcattcac
cgtgatctcaaacttgggaatctgttcctcaatgatgacatggatgtgaagatcggtgac
tttggtttagccactaagattgagtttgatggggagcgaaagaagaccctttgtggcacg
ccaaactacattgctcctgaggtgctctgcaagaaaggccacagctttgaagttgacatt
tggtcactaggatgcattctatacacactgctggttggaaaacctccatttgagacatcc
tgtctgaaagagacctacattaggattaagaagaatgagtactcggttcctagacacatt
aatccagttgcatctgctttgattcgtcggatgctgcacgctgaccctacactcagacct
tctgtagctgaactgctgactgatgagtttttcacctctggttatgcacccatgcggctg
cccacttcctgtctcactgttcctcccaggttctccatcgccccctccagcctggatcct
gccctcctccgcaaacctctctcatcacttaataaaggcacagatagtccaattgaggaa
atggggaaaatggatcagccacaaagagaagatctgcaacaaagagatggaccagagcag
cctgacactcacctaactgacatgcttcagcagctggctgtcgtcaatgcagccaagccg
tctgatagagactttattagacaagaggaagctgaagaccctgcttgtattcctgtcttc
tggattagcaaatgggttgactactctgacaaatatggccttggttaccagttgtctgat
aacagtgtaggtgttctgttcaatgattccacacggttgatcatgtgtgctgacggtgat
agcctgcagtacatcgaccgcaactctctagaatcctacctcagtgttcgctcgtatccc
tctgcactctccaaaaagattacactccttaagtacttcaggaattacatgagtgagcac
ttgctgaaggctggagcgaatataactcctcgggaaggggatgaactgacccgattgcct
taccttcgccactggttccgcacaaagagtgctattgtgctacacctgagtaatgggact
gtgcaaatcaattttttccaggatcacactaagcttattttgtgtccactaatgggagca
gtgacgtacatcaatgagaagcgagagttttacacctacaagatgaccttaatcgaggag
ttcggctgctgtaaagagttggctagccgtttgcgctatgctcgcaacatggtggagaag
ctcatggcctgcaaaagcagcacaacagctgctacttcagcacgctaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (32)   
   KEGG ORTHOLOGY (1)   
   RefGene (26)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
3D Structure (8)   
   PDB (8)   
Protein domain (7)   
   Pfam (7)   
All databases (66)   

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