KEGG   Danio rerio (zebrafish): 494453
Entry
494453            CDS       T01004                                 
Symbol
tln1
Name
(RefSeq) talin-1
  KO
K06271  talin
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04510  Focal adhesion
dre04820  Cytoskeleton in muscle cells
Brite
KEGG Orthology (KO) [BR:dre00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    494453 (tln1)
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    494453 (tln1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:dre04147]
    494453 (tln1)
Exosome [BR:dre04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   494453 (tln1)
  Exosomal proteins of other cancer cells
   494453 (tln1)
SSDB
Motif
Pfam: VBS Talin_middle I_LWEQ Talin_R4 FERM_f0 FERM_M FERM_N ACBP
Other DBs
NCBI-GeneID: 494453
NCBI-ProteinID: NP_001009560
ZFIN: ZDB-GENE-031002-48
Ensembl: ENSDARG00000100729
UniProt: Q5U7N6
Position
10:6121494..6313908
AA seq 2538 aa
MVALSLKIGVGNVVKTMQFEPSTVVYDACRIIRERVPEAQLGQPSDYGLFLSDDDPKKGI
WLEAGKALDYYMLRNGDTLEYKKKQRPLKIRMLDGTVKTVMVDDSKIVSDMLMTICARIG
ITNYDEYSLVRDVGEEKKEETTGTLKRDKTLLRDDKKMEKLKQKLHTDDELNWLDHGRTL
REQGVEESEMLLLRRKFFYSDQNVDSRDPVQLNLLYVQARDDILNGSHPVSFDKACEFAG
YQCQIQFGDHNESKHKPGFLDLKEFLPKEYVKNKGEKRIFQAHKNCQNMTEIEAKVNYVK
LARSLKTYGVSFFLVKEKMKGKNKLVPRLLGITKESVMRVDEKTKEVIQEWSLTNIKRWA
ASPKDFGDYQDGYYSVQTTEGEQIAQLIAGYIDIILKKKKSKDHFGLEGDEESTMLEDSV
SPKKSTVLQQQFNKMGKVETGSVALPAIIRSGAGGPESMKMGSMPQAKQHITSGQMHRGH
MPPLTSAQQALTGTINSSMQAVQAVQASLDEFDALPPLGTDSASQAWRKNKMDESKHEIH
SQVDAITAGTASMVNLTAGDPAETDYTAVGCAVTTISSNLTEMSKGVKLLAALMEDEGGN
GQQLLGAAKNLACAVSDMLKTAQPSSTEPRQNLLQAAGNVGQASGELLQQIGESDADQHF
QDMLMQLAKAVANAAAALVLKAKNVAQKSEDSAQQNKVIAAATQCALSTSQLVACTRVVV
APTISSPVCQEQLIEAGKLVAKSVEGCVEASHGATGDEHLLKQVGAAATGVTQALNELLQ
HIRQYASGGQPIGRHGEATDRILDVTDNIFSSMGDAGEMVRQARILAQATSDLVNAIKAD
AEGESDLENSRKLLSAAKLLADATARMVEAAKGAAANPDSEEQQQKLREAAEGLRMATNA
AAQNAIKKRLVNKLENAAKQAAAAATQTIAAAQHAASSNKNPAAQQQLVQSCKVVADQIP
QLVQGLRSSQAQPDSPSAQLALIGASQNFLQPGAKMVTAAKATVPTISDQASAMQLSQCA
KNLASALAELRTAAQKAQEACGPLEIDNALTMVRGLERDMQEAKASAAEGKLRPLPGETL
EKCSQDLGSSTKAVSSAIAQLLSEATQGNENYTGMAARDVAQALRSLASAARGVAANTED
PLARNAMLDCTGDVMDKSASLIEETKRAIAKPGDPDSQQRLAQVAKAVSQALNRSVNCLP
GQRDVDNAIRTVGEASKKLLSDKFPASGKNFQEAQANLNEAAAGLNQSANELVQASRGTT
QDLAKASGKFGQDFNQFLQAGVDMAGQSQSKEDQTQVVTNLKTISMSSSKLLLAAKALST
DPNSPNLKNQLAAAARAVTDSINQLISMCTQQAPGQKECDNALRELETVGGMLENPTEAV
NDLGYFDCIDSVMENSKVLGEAMAGISHNAKNSNLPEFGDSVSSASKALCGLTEAAAQGA
YLVGVSDPNSHAGQKGLVDPSQFARAKQSIQMACQNLVDPACTQSQVLSAATIVAKHTSA
LCNACRLASSKTSNPVAKRQFVQSAKEVANSTANLVKSIKALDGAFNQENRQKCKEATGP
LIEAVDNLTAFASNPEFASVPAQISPEGLAAMEPITAAAKAMLESSTGLIQTARSLAVNP
KDPPKWSVLAGHSRTVSDSIKKLITNMREKAPGQRECDDAIEVLSNCIREVDKASLAAIS
QQLTPRDDISHEALHEQMAASVHEISNLIEPVAIAARADASQLGHKVSQMVSYFEPLIMA
AIGTASKILNSQQQMNVLDQTKTLAESALQMLYTAKETGGNHKAAHTQEALEESVQMMKE
AVDDLGSTLAEVASAAGAVGGMVNSITQSINKMEDGPAFEPEGTFVDYQTTMVKTAKAIA
VTVQEMVTKSNTNPDELGGLANQLTTEFGDLASEAKCAAMTAENDEIGSHIKKQVTELGY
TCTGLVSKAGALQCSPNDSYTKKELIDSARKVSEKVSHVLAALQAGNRGTQACITAASAV
SGIIADLDTTIMFATAGTLNRENAETFADHREHILKTAKVLVEDTKLLVSGAGASQEKLA
QAAQSSVNTITKLADVVKLGAASLGSEDPETQVVLINAVKDVAKALGDLISATKAAAGKP
HDDPAMLQLKNSAKVMVTNVTSLLKTVKAVEDEATKGTRALEATIEHIKQELAVFSSADP
PPKTATPEEFIRMTKGITLATAKAVAAGNSCRQEDVIATANLSRRAVADMLRSCKQAAYH
PEVKREVQTRALRFGSECSTSYLGLLEHVLVIIQKPSHDLKQQLANYSKRVASSVTELIQ
AAEAMKGTEWVDPEDPTVIAENELLGAAAAIEAAAKKLEQLKPRAKPKEADESLNFEEQI
LEAAKSIAAATSALVKAASAAQRELVAQGKVGAIPANAVDDGQWSQGLISAARMVAAATN
NLCEAANSAVQGHASEEKLISSAKQVAASTAQLLVACKVKADQDSQTMKRLQAAGNAVKR
ASDNLVKAAQKAAFEAQDDQAVMVKSKMVGGIAQIIAAQEEMLRKEKELEEARKKLAMIR
QQQYKFLPSELREDGQEQ
NT seq 7617 nt   +upstreamnt  +downstreamnt
atggtggcgctgtcgctgaagatcggggtggggaatgtggtgaagacgatgcagtttgag
ccctccacagtggtgtacgacgcctgtcgaatcatcagggagagagttccagaagcacaa
ctcggccagcccagtgactatggcctgttcctgtcagacgatgatccaaagaagggcatt
tggctggaagcaggcaaagccctggattactacatgcttcgaaacggggatactctggag
tacaaaaagaaacagagacccctgaagattcgcatgttggatggaacggtcaaaacagtt
atggtggatgactcaaaaatcgtcagtgacatgctaatgaccatctgtgccagaataggc
atcacaaattatgatgagtactcactggtgcgtgacgtgggagaggaaaagaaggaagag
accacaggaacactgaagagagacaagaccctcctgagagatgacaaaaaaatggagaaa
ctcaaacagaaacttcacacagatgacgagctgaattggttggatcatgggcggacgctg
cgggagcagggtgtggaggagtctgagatgctgcttcttaggagaaagttcttctactca
gaccagaatgtggattccagagaccctgtacagctcaacctgttgtatgtgcaggcccgt
gatgacattttgaacggctctcaccctgtctccttcgataaggcctgtgagtttgctgga
taccagtgccagattcagtttggagaccacaatgagtccaaacacaaacctggattccta
gatttgaaggaattcttgcccaaagagtacgtcaagaacaagggcgagaagaggatcttt
caggcacacaaaaattgccaaaacatgaccgagatcgaggccaaagtcaactatgtcaaa
ctagccagatctctgaaaacatacggagtgtccttcttcttagtcaaggaaaaaatgaaa
ggaaagaataagctcgtgccgcgtttgttgggcatcactaaagagagtgtgatgagagtg
gatgagaaaaccaaagaggtgattcaggagtggagtctgaccaacatcaaacgctgggca
gcttctcctaaggactttggagactatcaggatggttactactcagttcagaccactgaa
ggagaacagattgcacaactcattgctggatacattgacatcattctcaaaaagaaaaag
agcaaagatcacttcggcctggagggagatgaagagtcaaccatgttggaggactccgtc
tctccgaaaaagtcaacagttcttcagcagcagtttaataagatggggaaggtggagacg
ggttctgtcgctctaccggccatcatccgatctggtgctggaggtccagagagcatgaag
atgggctcaatgccacaggccaaacagcacatcaccagcggtcagatgcacagaggacat
atgccccctctgacttcagctcagcaggctttaactggcaccattaactccagcatgcag
gcagtacaggcggttcaggcttctcttgatgagtttgatgccctgcctccactggggact
gattcggcatctcaagcctggaggaagaacaaaatggatgagtccaaacacgagattcac
tctcaggtggatgccatcactgcgggaactgcttccatggtcaatctgactgcaggtgac
ccggccgagacagattacactgctgtgggctgtgccgtcaccaccatctcctccaacctg
acggagatgtccaagggtgtcaaactgctggcggcgctgatggaggacgagggcggaaat
ggccagcagcttctgggtgctgcaaagaacctggcgtgtgccgtgtctgatatgctcaag
actgctcagccgtccagcactgagccacgacagaacctcctgcaagcagcgggtaatgtg
ggtcaggccagcggtgaactcctgcagcagatcggggagtctgatgcggatcagcacttc
caggacatgttgatgcagttggcgaaggctgtggcgaatgcagcagcggctctggtgtta
aaggctaaaaacgtggctcagaaaagcgaagattcagctcaacaaaacaaagtgatcgct
gctgccacccagtgcgccctctccacatcacagctggtggcctgcacacgagtggtggtg
gctccaaccatcagctcacccgtgtgtcaagagcagctcatcgaggctggaaaactggtg
gcgaagtctgtggagggctgtgtggaggcgtcacacggggcgaccggtgacgagcatctg
ctcaaacaggtgggcgccgctgccacaggagtcactcaggctcttaacgagctgctgcag
catattagacagtacgccagcggaggacagccaatcggacggcacggagaggctaccgac
cgcatcctggatgtgactgataacatcttcagctccatgggagatgcaggggagatggtg
cgtcaggcgcggatccttgctcaggccacctcagacctggtcaacgcgatcaaggcggac
gcagagggagaatctgacctggagaactctcgcaaactcctctctgcagccaaactcctg
gctgacgctactgcccgtatggtggaagctgcgaagggtgcagctgctaatccagacagc
gaggagcagcagcagaagttgcgtgaagctgcagagggactgcgcatggccaccaatgct
gcagcacagaacgccattaaaaagagactcgtcaacaaactggagaatgcagcgaaacaa
gccgcagcagccgccactcagaccatagcagccgctcaacatgcagcttcatccaacaag
aaccctgcggcccagcaacaactcgtacagagctgcaaggtggtggcggatcagatccca
cagctggttcagggtctgaggagcagccaggctcaacctgacagccccagcgctcaactc
gccctcatcggagctagccagaacttcctgcagcccggagccaaaatggtgaccgcagcc
aaagctacagttccaaccatcagtgaccaggcgtctgccatgcagctcagtcagtgcgct
aaaaacctggccagtgctctggctgagctccgcacggccgcccagaaggctcaggaggcg
tgtggtccgttggagattgataacgctctgactatggtacgggggctggagagggacatg
caggaggccaaagcttcagctgctgagggcaaactcagacccctgcctggagaaacgctg
gagaagtgctctcaggatctgggctccagcactaaagccgtgagctctgccattgctcag
ctcctcagtgaagcaactcaaggcaatgagaactacacaggtatggctgctcgtgatgtg
gctcaggctctgcgctcgctggcttcagccgctcgtggagtggcagccaacactgaagat
cctctagcccgtaacgcaatgctggactgcaccggcgatgtcatggacaaatccgccagc
ctgattgaagagaccaagagggccatagccaaaccaggagaccctgacagtcagcaaaga
ctggcccaggtagccaaggctgtgtctcaggcactgaaccgctctgtaaactgtctgccg
gggcagagggatgtggataatgccatcagaactgtcggggaagctagcaagaaactgctg
tctgataaatttccagcgagtgggaagaatttccaagaggctcaggccaatctgaacgag
gctgcagctggactaaaccagtcagccaatgagctggtgcaggcctcgcgtggcaccacc
caggacctggccaaagcctccgggaagtttggacaagactttaaccaattcctgcaggct
ggagtggacatggctggacaatcccagtctaaagaagaccaaactcaagtggtcaccaac
ctgaagaccatctccatgtcctccagcaaactcctgctggcggctaaagctctgtccaca
gaccccaactcgccaaatctgaagaaccaactcgctgctgctgctcgcgcggtgacagac
agcattaatcagctgatcagcatgtgtacccagcaggctccgggacagaaggagtgtgac
aacgctctccgtgagcttgagacggttggaggaatgctggagaacccaacagaagcagtc
aatgatttgggctactttgactgcattgacagtgtgatggagaactcaaaggttttgggt
gaggccatggctggcatttcccataatgccaaaaacagtaacttgccagagtttggagat
tcggtcagttcagcgtctaaagcgctgtgtggtctcactgaagcagctgctcagggggcg
tatctggttggtgtgtcagacccgaacagccatgctggccagaagggtcttgtggacccc
tcacaatttgccagagccaaacagtccatccagatggcctgtcagaacctggtggatcca
gcctgcacccagtcccaggttctctctgctgccaccatcgttgccaaacacacttcggcc
ttgtgcaatgcctgccggctcgcctcctccaagacatccaacccagttgctaagagacag
ttcgtccagagtgccaaagaggtggccaacagcacagccaacctcgtcaagtccatcaag
gctctcgacggggcctttaaccaggaaaacagacagaagtgtaaggaagccactgggcca
ctcattgaggctgtggataacctgactgccttcgcttcaaacccagagttcgcaagtgta
cccgctcagatcagcccagagggtctggctgcgatggagccgatcacagcagccgctaag
gcaatgttggaaagctcgacaggactgatccagacggctcgctcgctcgcagtcaacccg
aaagatccacccaagtggtctgtgcttgctggacactccagaacagtgtccgactccatc
aagaaactcatcactaacatgagggaaaaggctccgggtcagagggagtgtgatgatgcc
attgaggttcttagtaactgcattcgtgaagtggacaaggcctcgctggcagccatcagt
cagcagctcacgcctagagacgacatttcccatgaggctctgcacgagcagatggcggcg
tctgtgcatgagatcagtaacctgattgaaccagtggccatcgcagcccgtgctgatgcc
tctcagctgggacacaaggtgtctcagatggtcagttactttgaaccgctcatcatggct
gccatcggcacagcgtctaagatcctgaacagccagcagcagatgaacgtgctggaccaa
accaagactctggctgagtctgcgctacagatgctctatacggccaaagagactggagga
aaccacaaggcggcgcacacacaagaggctctggaggagtctgttcagatgatgaaggag
gcggtggacgatctgggttcgactctggcagaagtggccagcgctgcaggagcagtggga
ggaatggtcaactccatcactcagtccatcaacaagatggaggacggacctgccttcgag
cctgaaggaacgtttgtggattatcagaccaccatggtgaagacagccaaagctatcgct
gtcaccgttcaggagatggttaccaaatccaacaccaaccctgatgagctgggcggtttg
gccaatcagctgaccacagagttcggtgacctcgcatcagaggccaaatgtgcagccatg
actgctgaaaacgatgagatcggttcacatatcaagaagcaggtgactgagttgggctac
acctgcactggtctggtcagtaaagcaggagcgctacagtgcagtccaaacgactcctac
actaagaaggagctcattgacagtgccaggaaagtctctgagaaggtctctcatgtgctg
gcagctcttcaggcaggcaatcgtggcactcaggcctgcattactgccgcgagcgctgtc
tctggcatcattgctgatttagacaccaccatcatgtttgccaccgcgggcactctcaac
cgagagaacgcagagacatttgcagaccacagagagcacatcttaaagacggctaaagtt
ctggtggaggacacgaagctgctggtttctggagccggagcaagtcaggagaaactggct
caggctgcacagtcctccgtcaacaccatcaccaaactggccgatgtggttaaattgggg
gcagcgagtctgggctctgaagacccagagacacaggtggttctgatcaacgctgtgaag
gacgtggctaaagctctgggtgacctgatcagcgccaccaaagcagcggccggcaaacct
cacgatgaccccgccatgctgcagctcaaaaactctgctaaggtgatggtgaccaatgtg
acgtctctacttaaaaccgtgaaagccgtggaggatgaagccactaaaggcacacgagca
ctagaggccaccatagagcacatcaaacaagagctggctgttttcagcagtgcagatcct
cctccaaagacggccactccagaggagttcatccgcatgaccaaaggcatcacattggcc
acagctaaagcagtggctgctgggaactcctgccgtcaggaggacgtgatcgccactgct
aacctaagcagacgagctgtcgcagacatgctgcgctcctgcaagcaagccgcataccac
ccagaggtgaagcgggaggtccagactcgagcgctccgctttggctctgagtgctccaca
agttacctgggcctgctggagcacgtgttagtgatcattcagaaaccctcgcatgacctt
aaacagcagctggcaaactactccaaacgtgtggccagttcagtgaccgagctcatccag
gctgcggaggccatgaaaggtacggagtgggtggatcccgaagaccccaccgtcattgca
gaaaacgagctgctgggagccgcagctgccattgaagctgccgcgaagaaactagagcag
ctcaaaccccgagccaaacccaaggaagctgatgagagtctgaactttgaggaacagatt
ctagaagcggccaaatccatcgctgcagccaccagtgctctggtcaaagctgcgtctgcc
gctcagagagagctggtggctcaagggaaggttggggcaattccagcaaatgcggtggat
gatggacagtggtctcagggtctcatttcagctgctcgtatggtagctgcagctactaac
aacctgtgcgaagcagctaactctgcggttcagggtcacgccagcgaggagaaactcatt
tcttcagccaaacaggtggcagcatccaccgcacagctgctggtggcctgtaaggtcaag
gctgaccaggactcccagaccatgaagagactgcaggctgctggtaatgctgtcaagagg
gcgtctgataacctggtgaaggcggcacagaaggctgcgtttgaggctcaagatgatcag
gctgtgatggtgaagagcaagatggtgggcggtattgctcagatcatcgctgctcaggag
gagatgctcaggaaggagaaagagctggaagaagccagaaagaaactggcaatgatccga
cagcagcagtacaagttcctgccctcagagctgcgagaggacggacaggagcagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (2)   
   KEGG PATHWAY (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (26)   
   KEGG ORTHOLOGY (1)   
   RefGene (20)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (6)   
   UniProt (1)   
   RefSeq(pep) (5)   
DNA sequence (17)   
   RefSeq(nuc) (5)   
   GenBank (6)   
   EMBL (6)   
Protein domain (8)   
   Pfam (8)   
All databases (62)   

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