KEGG   Danio rerio (zebrafish): 796487
Entry
796487            CDS       T01004                                 
Symbol
cyp17a2
Name
(RefSeq) cytochrome P450 17A2 precursor
  KO
K00512  steroid 17alpha-monooxygenase / 17alpha-hydroxyprogesterone deacetylase [EC:1.14.14.19 1.14.14.32]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre00140  Steroid hormone biosynthesis
dre01100  Metabolic pathways
Module
dre_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
dre_M00110  C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
dre_M00976  C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:dre00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    796487 (cyp17a2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:dre00199]
    796487 (cyp17a2)
Enzymes [BR:dre01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.19  steroid 17alpha-monooxygenase
     796487 (cyp17a2)
    1.14.14.32  17alpha-hydroxyprogesterone deacetylase
     796487 (cyp17a2)
Cytochrome P450 [BR:dre00199]
 Cytochrome P450, animal type
  CYP17 family
   796487 (cyp17a2)
SSDB
Motif
Pfam: p450 Pro-rich_19
Other DBs
NCBI-GeneID: 796487
NCBI-ProteinID: NP_001099140
ZFIN: ZDB-GENE-100822-1
Ensembl: ENSDARG00000053966
UniProt: A7U483
Structure
Position
23:complement(45560534..45568816)
AA seq 495 aa
MCSVSVCVCFSALLLLLLLLVRRLLEGVGSSSVSFPCLPRLPLLGSLLHLRSNLPPHLLF
TQLSSQYGPLFGLYAGPHLTLVVSEIGLVREVLLQRGREFAGRPKMVTTDLLTQGGKDIA
FADYSPLWKNHRRLVHSSFTLFGEGSNKLQTIVQEAADSLCEELQACRGQSSDLSVVLMR
AVTNVICRLVFSSSYQPSDPELQTVIQYNDGIVQTIARGGLVDIFPWLRIFPNKDLKRLK
ECVSIRDQLLYKKLLEHKKSLTPGEPRDLLDALLIGQQRGSGGADDITEDHVLMTAAEAF
GAGVETTSTTLLWTIAFLLHHPQLQERVQAELDECVGVDRPPCLSDRPHLPLLDAVLCEV
MRIRPVSPILIPHVAMQDTSLGGHSVPKGTRVLVNMWAIHHDPKHWDQPEQFNPERFLEP
SGKKKTQSSFLPFGAGPRVCVGESLARIELFLFVSRPLQRFSFSCPSEASLPDLQGRFGV
VLQPERYTVTVTPRH
NT seq 1488 nt   +upstreamnt  +downstreamnt
atgtgttcagtgagtgtgtgtgtgtgtttctctgctcttcttcttctcctcctgctgtta
gtcaggcgtctgctggagggtgtgggctcctccagtgtgtcgttcccgtgtctgccgcgc
ctgccgctgttggggagtttactgcatctgcgctccaatctcccgccacacctgctcttc
actcagctgtcgtctcagtacgggccgctgtttgggctttatgccgggccgcacctcacg
ctggtggtcagtgagatcggtctggtcagagaagtgctgctgcagcggggcagagagttc
gccggacggcccaagatggtgaccaccgacctgttgactcagggtgggaaggacattgcg
tttgcagactacagtccactgtggaagaaccaccggcgtctagtgcactcctcgtttaca
ctgttcggcgagggctcaaataaactgcagaccatcgtgcaggaggcggctgacagtctg
tgtgaggagctccaggcctgcaggggtcagagttcagatctgagtgtggtgttgatgcgc
gccgtcactaacgtgatctgcaggctggtgttcagctcctcctatcagcccagcgacccc
gagctgcagaccgtcatacagtacaacgacggcatcgtgcagaccatcgccagaggggga
ctcgtggacatcttcccctggttaagaattttccccaacaaggacctgaagaggctaaag
gagtgtgtttccatacgagaccaactactgtacaagaaactgctggagcacaagaagagc
ctgacacctggagagccgcgtgacctgctggatgctctcctgattggtcagcaaagaggg
tcaggtggtgctgatgacattacagaggatcacgtgctgatgacggcggccgaggctttc
ggagctggagtggagacgacatccactacactactgtggaccatagcgttcctgctgcac
cacccacagctgcaggagcgtgttcaggcagagctggatgagtgtgtcggtgtggatcgt
cctccgtgtctctctgatcgtcctcatctgccgctgctggacgctgtgctctgtgaggtg
atgcgcatccgtcccgtcagcccaatcctcatcccgcacgtcgctatgcaggacaccagt
ttggggggtcacagtgttcctaaagggacgcgtgttctggtgaacatgtgggcgattcat
cacgaccccaaacactgggaccagcctgagcagtttaaccctgagcgcttcctggagcca
tcagggaagaagaagactcagtccagcttcctgccgttcggtgcgggtccgcgggtgtgt
gttggagaatctctagccagaattgagctctttctgtttgtctctcgccccctgcagcgc
ttcagcttcagctgtccatcagaggcttcattgccggatctgcagggccgcttcggggtg
gtgttacagcctgagcgctacacggtcacagtcacacctcgacactga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (2)   
   KEGG MODULE (4)   
Chemical substance (20)   
   KEGG COMPOUND (20)   
Chemical reaction (11)   
   KEGG ENZYME (2)   
   KEGG REACTION (9)   
Genome (1)   
   KEGG GENOME (1)   
Gene (27)   
   KEGG ORTHOLOGY (1)   
   RefGene (21)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (2)   
   Pfam (2)   
All databases (77)   

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