KEGG   Desulfohalobium retbaense: Dret_1459
Entry
Dret_1459         CDS       T00989                                 
Name
(GenBank) 2-isopropylmalate synthase
  KO
K01649  2-isopropylmalate synthase [EC:2.3.3.13]
Organism
drt  Desulfohalobium retbaense
Pathway
drt00290  Valine, leucine and isoleucine biosynthesis
drt00620  Pyruvate metabolism
drt01100  Metabolic pathways
drt01110  Biosynthesis of secondary metabolites
drt01210  2-Oxocarboxylic acid metabolism
drt01230  Biosynthesis of amino acids
Module
drt_M00432  Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:drt00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00620 Pyruvate metabolism
    Dret_1459
  09105 Amino acid metabolism
   00290 Valine, leucine and isoleucine biosynthesis
    Dret_1459
Enzymes [BR:drt01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.13  2-isopropylmalate synthase
     Dret_1459
SSDB
Motif
Pfam: HMGL-like LeuA_dimer AP_endonuc_2
Other DBs
NCBI-ProteinID: ACV68746
UniProt: C8X2U9
Position
complement(1687865..1689400)
AA seq 511 aa
MAEKLIIFDTTLRDGEQSPGATMNHHEKVRLARQLDKLGVDVIEAGFPASSQGDFEAVQA
ISRAVTNCQVAGLCRSVLSDIDRAWEALQDAPKARIHTFIATSDIHMEHKLGKSRSEVLD
MARKAVSHAASYTSNVEFSAEDASRSDWDFLVQVVQVAVDAGATTVNIPDTVGYSQPQEF
ARLVRYLQDNVPALGNEVVLSVHCHNDLGLAVANTLAAVEAGARQAEVTLSGIGERAGNA
SVEEVVMNLNVRKDYFQIETGVHTEQLFPSCRLLSLIIGQPIPPYKPVVGPNAFAHESGI
HQHGMLKNRQTYEIMTPESVGRAGTDMVLGKHSGKAAIKARLEELGYSLTDEQLVTVVEA
IKRLADKKKRLYVEDLEAVVLEEIYRLPDKFKLNYLNTVSGNMALPTAALELTIDGEEHR
LADFGVGPIDAVFNTIAKLTKRSPKLVRYSVNAITGGTDAQGEVTVRLEEHGRSAVGRGS
DPDVIMASARAYLNALNRLAKKEEEKICATL
NT seq 1536 nt   +upstreamnt  +downstreamnt
atggctgaaaaattgatcatttttgacaccacactgcgagacggagagcaatcccctggc
gcgaccatgaaccaccacgaaaaggtgcgtctggccaggcaattggacaagctcggcgtt
gacgttatcgaggcgggattccccgcgtccagccagggcgatttcgaggcggtccaggcc
atcagtcgcgcggtgaccaactgtcaggtggccgggctctgccgctcggtcctctctgat
atcgaccgcgcctgggaggcgcttcaggacgcgcccaaggcccggatccacacttttatc
gccacctccgacatccatatggaacataagctcggcaaaagccgcagcgaggtgttggac
atggcccgtaaggcggtcagccacgcggcctcgtatacatccaacgtcgagttctccgcc
gaggacgcctcccgctccgactgggattttctggtccaggtggttcaggtggctgtggat
gccggcgcaacgacagtgaacatcccggatacggtcgggtattcccagcctcaggagttc
gcgcgtttggtccggtatctgcaggacaatgtgccggctttaggcaatgaggtcgtgttg
agtgtgcactgccacaatgatctgggcctggcggtggccaataccctggcagcggtcgag
gccggagcacggcaggccgaagtgaccctgagcggcatcggtgagcgcgccggcaacgcc
tcggttgaggaagtggtcatgaacctcaatgtgcgcaaggactacttccagatcgagacc
ggcgtgcacacggaacagctctttccctcctgccggctgctctcgctgatcatcgggcag
cccatcccgccctacaaaccggttgtcggccccaatgcctttgctcacgaatcggggatc
caccagcacggcatgctcaaaaatcgccagacgtatgagatcatgaccccggaatctgtg
ggccgcgccggcacggacatggtactgggcaagcactcgggcaaggccgccatcaaggcc
cggctggaggaactcggctacagcctgacggacgagcagctggtgaccgtggttgaggcc
atcaaacggctggcggacaagaaaaaacggctctatgtcgaggatctggaggccgtggtc
ctggaagagatctaccgcctgccggataaattcaaactcaactacctgaataccgtctcc
gggaatatggccctgcccacggcggcattggaattgaccatcgacggtgaggagcaccgg
ctcgcggatttcggagtcggtcccatcgacgctgttttcaacaccatcgcgaaattgacc
aagcgctcacccaaactggtgcgctattcggtcaacgccatcaccggcggaacagacgct
cagggcgaagtgacggtccggcttgaagaacatggccgcagcgcggtcggccgcggctcg
gatccggatgtgatcatggccagtgcccgggcctatctcaacgccttgaaccgcttggcg
aaaaaggaggaagaaaagatatgcgccacactgtag

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (7)   
   KEGG PATHWAY (6)   
   KEGG MODULE (1)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (14)   
   NCBI-PROTEINID (1)   
   OC (1)   
Protein sequence (1)   
   UniProt (1)   
Protein domain (3)   
   Pfam (3)   
All databases (38)   

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