KEGG   Equus asinus (ass): 106827252
Entry
106827252         CDS       T04645                                 
Symbol
APAF1
Name
(RefSeq) apoptotic protease-activating factor 1 isoform X1
  KO
K02084  apoptotic protease-activating factor
Organism
eai  Equus asinus (ass)
Pathway
eai01524  Platinum drug resistance
eai04115  p53 signaling pathway
eai04210  Apoptosis
eai04215  Apoptosis - multiple species
eai05010  Alzheimer disease
eai05012  Parkinson disease
eai05014  Amyotrophic lateral sclerosis
eai05016  Huntington disease
eai05020  Prion disease
eai05022  Pathways of neurodegeneration - multiple diseases
eai05134  Legionellosis
eai05152  Tuberculosis
eai05160  Hepatitis C
eai05161  Hepatitis B
eai05162  Measles
eai05164  Influenza A
eai05168  Herpes simplex virus 1 infection
eai05169  Epstein-Barr virus infection
eai05200  Pathways in cancer
eai05222  Small cell lung cancer
eai05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eai00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04210 Apoptosis
    106827252 (APAF1)
   04215 Apoptosis - multiple species
    106827252 (APAF1)
   04115 p53 signaling pathway
    106827252 (APAF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106827252 (APAF1)
  09162 Cancer: specific types
   05222 Small cell lung cancer
    106827252 (APAF1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    106827252 (APAF1)
   05160 Hepatitis C
    106827252 (APAF1)
   05164 Influenza A
    106827252 (APAF1)
   05162 Measles
    106827252 (APAF1)
   05168 Herpes simplex virus 1 infection
    106827252 (APAF1)
   05169 Epstein-Barr virus infection
    106827252 (APAF1)
  09171 Infectious disease: bacterial
   05134 Legionellosis
    106827252 (APAF1)
   05152 Tuberculosis
    106827252 (APAF1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106827252 (APAF1)
   05012 Parkinson disease
    106827252 (APAF1)
   05014 Amyotrophic lateral sclerosis
    106827252 (APAF1)
   05016 Huntington disease
    106827252 (APAF1)
   05020 Prion disease
    106827252 (APAF1)
   05022 Pathways of neurodegeneration - multiple diseases
    106827252 (APAF1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    106827252 (APAF1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    106827252 (APAF1)
SSDB
Motif
Pfam: WD40 NB-ARC APAF1_C APAF-1-like_WHD ANAPC4_WD40 CARD NBCH_WD40 eIF2A RMC1_N WD40_like Ge1_WD40 Nup160 CARD_2 AAA_16 Utp8 AAA_22 AAA_18 NACHT
Other DBs
NCBI-GeneID: 106827252
NCBI-ProteinID: XP_014690482
UniProt: A0A9L0I6J1
Position
2:26946480..27022412
AA seq 1256 aa
MDAKARNCLLQHREALEKDIKTSYIMDYMIGDGVLTVSEEEKVKNEPTRQQKAAMLIKMI
LKKDNYCYISFYKALLQEGYKDLAALLHGGIPVISSSNGKDSLVGVTSYVKTVLCEGGVP
QRPVVFVTRKKLVHTIRQKLLKLDGEPGWVTIYGMAGCGKSVLAAEAVRDHTLLEGCFPG
GVHWLSVGKQDKSGLLMKLQNLCTRLDQDESFSQRLPLNIEEAKDRLRILMLRKHPRSLL
ILDDVWDPWVLKAFDNQCQILLTTRDRSVTDSVMGPKYVIPVESGLGKEKGLEILSLFVN
MKKADLPEQAHSIIKECKGSPLVVSLIGALLRDFPNRWEYYLRQLQNKQFKRIRKCSSYD
YEALDEAMSISVEMLREDIKDYYTDLSILQKDVKVPTKVLCILWDMETEEVEDILQEFVN
KSLLFCDRNGKSFRYYLHDLQVDFLTEKNRNQLQDLHRKIITQFQRHHRLHTLSPDQEDC
MYWYNFLAYHMASANMHKELCALMFSLDWIKAKTELVGPAHLIHEFVEYRHILDEKEISV
CSQDCSVCENFQEFLSLNGHLLGRQPFPNIVQLGLCEPETSEVYQQAKLQAKQEVDNGTL
YLEWINKKNIKNLSRLVVRPHTDAVYHACFSGDGQRIASCGADKTLQVFKAETGEKLLEI
KAHEDEVLCCAFSTDDRFIATCSVDKKVKIWNSMTGELVHTYDEHSEQVNCCHFTNNSHH
LLLATGSSDSFLKLWDLNEKDCRNTMFGHTNSVNHCRFSPDDKLLASCSADGSLKLWDVK
SANERKSINVKQFFISSEEPQEDMEVIVKCCSWSSDGARIMVAAKNKIFLVDVHTCGLLA
EIHTGHHSTIQYCDFSPSNHLAVVALSQYCVELWNMDSCLKVADCRGHLSWVHSVMFSPD
GSSFLTSSDDETIRLWETKKVCKNSGIVLKQEIDVLFQENEVMILAVDNMRRLQLINGKT
GQIDYLTEAQVSSCCLSPNLQYVALGGEDGAIKILELLNNRIFQSKIGHKSAVRHVQFTT
VGKTLISSSDDSVIQVWNWQSEEYVFLQAHQETVKDFRLLRNSRLLSWSFDGTVKVWNII
TGRIEKDFVCHQDTVLSCDISPDATKFSSTSADKTAKIWSFELLSPLHELRGHKGCVRCS
VFSGDSTLLATGDDNGEIRIWNVSNGELLHLCAPISVEEGAATHGGWVTDLCFSPDSKML
VSAEGSLKWWNAVTGESSQTFYTNGTNLKKIHVSPDFKTYVTVDNLGILYILQVLE
NT seq 3771 nt   +upstreamnt  +downstreamnt
atggatgcaaaagctcgaaattgtttacttcaacatagagaagccctggaaaaggacatc
aaaacctcctacatcatggattacatgattggtgatggagttttaacagtatcggaggag
gaaaaagtaaaaaatgagcccactcgacagcaaaaagcagctatgttaattaaaatgata
cttaaaaaggataattattgctacatatcattctacaaggctctactacaagaaggatat
aaagatcttgctgcccttctccatggtggcattcctgttatctcttcttccaacggcaaa
gattcgcttgttggagtaacttcatatgtaaagacagtcctgtgtgaaggtggagtacca
cagaggccagttgtttttgttactagaaagaagctggttcatacaattcggcagaaactc
ctcaaattggatggtgaaccgggatgggtcaccatttatggaatggcaggttgtgggaag
tctgtattagctgcagaagctgttcgagatcataccctcttagaaggttgtttcccaggg
ggtgtgcattggctttcagttgggaaacaagacaaatctggacttctgatgaaactgcag
aatctttgcacacgattggatcaagatgagagtttctcccagaggcttccacttaatatt
gaagaggctaaagaccgtctccgcattctgatgctgcgcaaacacccaaggtctctgttg
atcttggatgatgtttgggatccttgggtattaaaagcttttgacaatcagtgtcagatt
cttcttacaaccagagacaggagtgttacagattcagtaatgggtcctaaatacgtaatc
cctgtggagagtggcttaggaaaagaaaaaggacttgaaattttatccctttttgttaat
atgaagaaagcagatttgccagaacaagctcacagtattataaaagagtgtaaaggttct
cctcttgtagtgtctttaattggtgcacttttacgtgattttcccaaccgctgggagtac
tacctcaggcaacttcagaataagcaatttaagaggataaggaaatgttcatcttatgat
tatgaagctctggatgaagccatgtctataagtgttgaaatgctcagagaagacatcaaa
gattattacacagatctttccatccttcaaaaggatgttaaggtgcctacaaaggtatta
tgtattctctgggacatggaaactgaagaagttgaagacatactgcaggagtttgttaat
aagtctctcttattctgtgatcgaaatggaaaatcatttcgttattatttacatgatctt
caagtagatttccttacagagaagaatcgcaaccagcttcaggatctgcacaggaagata
atcactcagttccagagacaccacaggctacatactctttcaccagatcaggaggactgc
atgtattggtacaattttctggcctatcacatggccagtgccaatatgcacaaagaactt
tgtgctttaatgttttccttggattggattaaagcaaaaacggaacttgtaggtcctgct
catctgattcatgaatttgtggaatataggcatatattggatgaaaaggagatttcagtt
tgttcacaggattgttcagtctgtgagaatttccaggagtttttatctttaaatggacat
cttcttggacgacagccatttcctaatattgtacaactgggtctctgtgaaccggaaact
tcagaagtttatcagcaagctaagctgcaggccaagcaggaggtcgataacggaacgctt
tacctggagtggataaacaaaaaaaacatcaagaatctctcccgcttagttgtccgcccc
catacagatgctgtttaccatgcttgcttttctggggatggtcaaagaatagcttcttgt
ggtgctgataaaaccttgcaggtgttcaaagctgaaactggagagaaacttttagaaatc
aaggctcatgaggatgaagtgctttgctgtgcattctctacagatgacagatttatagca
acctgctcagtggataaaaaagtgaagatttggaattctatgactggggaactagtacat
acctatgatgagcactcagagcaagtcaattgctgccacttcaccaacaacagtcatcac
cttctgttagccactgggtcaagtgactccttcctcaaactctgggatttgaatgaaaaa
gattgtcgaaataccatgtttggtcatacaaattcagtcaatcactgcagattttcacca
gatgataaacttttggctagttgttcagctgatggatcattgaagctttgggatgtgaaa
tcagcaaacgagaggaaaagcattaatgtgaagcagttctttataagttcagaggagcct
caagaggatatggaagtgatagtgaaatgttgttcatggtcttctgatggtgctagaata
atggtggcagcgaaaaataaaatcttccttgttgacgttcatacctgtggcctattggca
gaaatccatacaggtcaccacagcacgatccaatactgtgacttctccccaagtaaccat
ttggcggtggtagctttgtcccagtactgtgtggagttgtggaatatggactcgtgttta
aaagtagctgattgcagaggacatttaagttgggttcattctgtgatgttttctcctgat
ggatcatcatttttgacatcttctgatgatgagacaattaggctctgggagacaaagaaa
gtatgtaaaaactctggtatagtgttaaagcaagaaatagacgttctgtttcaagaaaat
gaagttatgattctcgcagttgacaacatgagacgtctgcaactcattaatggaaaaaca
ggtcagattgattatctgactgaagctcaagttagttcctgttgcttaagtccaaatctt
cagtatgttgcacttggaggagaagatggagccattaagattttagaactcctaaacaac
agaatcttccaatccaagattgggcacaagagcgctgtacggcacgtccagttcacaact
gttgggaagactcttatttcaagctctgatgattctgtaattcaggtatggaattggcaa
tcagaggaatatgtctttctgcaagcccatcaggaaacagtgaaagactttaggctcttg
agaaattcaagactgctttcttggtcttttgatggaacagtgaaggtgtggaatattatt
actggaagaatagaaaaagacttcgtctgtcaccaggatacagtactttcttgtgatatt
tctcctgatgctaccaagttttcatctacctctgctgacaagactgcaaagatttggagt
tttgaactcctttcccctcttcatgaattgaggggccataaaggctgtgtgcgctgctct
gtcttctctggggacagtacgctgttggcgactggagatgacaacggagaaatcaggata
tggaatgtctcaaacggtgagcttcttcatttgtgtgctccgatttcagtagaagaagga
gctgctacccacggaggctgggtgactgacctttgcttttctccagatagcaaaatgctt
gtctctgctgaaggatctcttaagtggtggaatgctgtcactggagaatcctcacagacc
ttctacacaaatggaaccaatcttaagaaaatacacgtgtcccctgacttcaaaacatat
gtgactgttgataatcttggtattttatatattttacaggttttagagtaa

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (21)   
   KEGG PATHWAY (21)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (6)   
   RefSeq(nuc) (6)   
Protein domain (18)   
   Pfam (18)   
All databases (56)   

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