KEGG   Equus asinus (ass): 106835678
Entry
106835678         CDS       T04645                                 
Symbol
NRAS
Name
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
eai  Equus asinus (ass)
Pathway
eai01521  EGFR tyrosine kinase inhibitor resistance
eai01522  Endocrine resistance
eai04010  MAPK signaling pathway
eai04012  ErbB signaling pathway
eai04014  Ras signaling pathway
eai04015  Rap1 signaling pathway
eai04062  Chemokine signaling pathway
eai04068  FoxO signaling pathway
eai04071  Sphingolipid signaling pathway
eai04072  Phospholipase D signaling pathway
eai04137  Mitophagy - animal
eai04140  Autophagy - animal
eai04150  mTOR signaling pathway
eai04151  PI3K-Akt signaling pathway
eai04210  Apoptosis
eai04211  Longevity regulating pathway
eai04213  Longevity regulating pathway - multiple species
eai04218  Cellular senescence
eai04360  Axon guidance
eai04370  VEGF signaling pathway
eai04371  Apelin signaling pathway
eai04540  Gap junction
eai04550  Signaling pathways regulating pluripotency of stem cells
eai04625  C-type lectin receptor signaling pathway
eai04650  Natural killer cell mediated cytotoxicity
eai04660  T cell receptor signaling pathway
eai04662  B cell receptor signaling pathway
eai04664  Fc epsilon RI signaling pathway
eai04714  Thermogenesis
eai04720  Long-term potentiation
eai04722  Neurotrophin signaling pathway
eai04725  Cholinergic synapse
eai04726  Serotonergic synapse
eai04730  Long-term depression
eai04810  Regulation of actin cytoskeleton
eai04910  Insulin signaling pathway
eai04912  GnRH signaling pathway
eai04915  Estrogen signaling pathway
eai04916  Melanogenesis
eai04917  Prolactin signaling pathway
eai04919  Thyroid hormone signaling pathway
eai04921  Oxytocin signaling pathway
eai04926  Relaxin signaling pathway
eai04929  GnRH secretion
eai04933  AGE-RAGE signaling pathway in diabetic complications
eai04935  Growth hormone synthesis, secretion and action
eai05010  Alzheimer disease
eai05022  Pathways of neurodegeneration - multiple diseases
eai05034  Alcoholism
eai05160  Hepatitis C
eai05161  Hepatitis B
eai05163  Human cytomegalovirus infection
eai05165  Human papillomavirus infection
eai05166  Human T-cell leukemia virus 1 infection
eai05167  Kaposi sarcoma-associated herpesvirus infection
eai05170  Human immunodeficiency virus 1 infection
eai05200  Pathways in cancer
eai05203  Viral carcinogenesis
eai05205  Proteoglycans in cancer
eai05206  MicroRNAs in cancer
eai05207  Chemical carcinogenesis - receptor activation
eai05208  Chemical carcinogenesis - reactive oxygen species
eai05210  Colorectal cancer
eai05211  Renal cell carcinoma
eai05213  Endometrial cancer
eai05214  Glioma
eai05215  Prostate cancer
eai05216  Thyroid cancer
eai05218  Melanoma
eai05219  Bladder cancer
eai05220  Chronic myeloid leukemia
eai05221  Acute myeloid leukemia
eai05223  Non-small cell lung cancer
eai05224  Breast cancer
eai05225  Hepatocellular carcinoma
eai05226  Gastric cancer
eai05230  Central carbon metabolism in cancer
eai05231  Choline metabolism in cancer
eai05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
eai05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106835678 (NRAS)
   04012 ErbB signaling pathway
    106835678 (NRAS)
   04014 Ras signaling pathway
    106835678 (NRAS)
   04015 Rap1 signaling pathway
    106835678 (NRAS)
   04370 VEGF signaling pathway
    106835678 (NRAS)
   04371 Apelin signaling pathway
    106835678 (NRAS)
   04068 FoxO signaling pathway
    106835678 (NRAS)
   04072 Phospholipase D signaling pathway
    106835678 (NRAS)
   04071 Sphingolipid signaling pathway
    106835678 (NRAS)
   04151 PI3K-Akt signaling pathway
    106835678 (NRAS)
   04150 mTOR signaling pathway
    106835678 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    106835678 (NRAS)
   04137 Mitophagy - animal
    106835678 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    106835678 (NRAS)
   04218 Cellular senescence
    106835678 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    106835678 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    106835678 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    106835678 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    106835678 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    106835678 (NRAS)
   04660 T cell receptor signaling pathway
    106835678 (NRAS)
   04662 B cell receptor signaling pathway
    106835678 (NRAS)
   04664 Fc epsilon RI signaling pathway
    106835678 (NRAS)
   04062 Chemokine signaling pathway
    106835678 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    106835678 (NRAS)
   04929 GnRH secretion
    106835678 (NRAS)
   04912 GnRH signaling pathway
    106835678 (NRAS)
   04915 Estrogen signaling pathway
    106835678 (NRAS)
   04917 Prolactin signaling pathway
    106835678 (NRAS)
   04921 Oxytocin signaling pathway
    106835678 (NRAS)
   04926 Relaxin signaling pathway
    106835678 (NRAS)
   04935 Growth hormone synthesis, secretion and action
    106835678 (NRAS)
   04919 Thyroid hormone signaling pathway
    106835678 (NRAS)
   04916 Melanogenesis
    106835678 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    106835678 (NRAS)
   04726 Serotonergic synapse
    106835678 (NRAS)
   04720 Long-term potentiation
    106835678 (NRAS)
   04730 Long-term depression
    106835678 (NRAS)
   04722 Neurotrophin signaling pathway
    106835678 (NRAS)
  09158 Development and regeneration
   04360 Axon guidance
    106835678 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    106835678 (NRAS)
   04213 Longevity regulating pathway - multiple species
    106835678 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    106835678 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106835678 (NRAS)
   05206 MicroRNAs in cancer
    106835678 (NRAS)
   05205 Proteoglycans in cancer
    106835678 (NRAS)
   05207 Chemical carcinogenesis - receptor activation
    106835678 (NRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    106835678 (NRAS)
   05203 Viral carcinogenesis
    106835678 (NRAS)
   05230 Central carbon metabolism in cancer
    106835678 (NRAS)
   05231 Choline metabolism in cancer
    106835678 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    106835678 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    106835678 (NRAS)
   05225 Hepatocellular carcinoma
    106835678 (NRAS)
   05226 Gastric cancer
    106835678 (NRAS)
   05214 Glioma
    106835678 (NRAS)
   05216 Thyroid cancer
    106835678 (NRAS)
   05221 Acute myeloid leukemia
    106835678 (NRAS)
   05220 Chronic myeloid leukemia
    106835678 (NRAS)
   05218 Melanoma
    106835678 (NRAS)
   05211 Renal cell carcinoma
    106835678 (NRAS)
   05219 Bladder cancer
    106835678 (NRAS)
   05215 Prostate cancer
    106835678 (NRAS)
   05213 Endometrial cancer
    106835678 (NRAS)
   05224 Breast cancer
    106835678 (NRAS)
   05223 Non-small cell lung cancer
    106835678 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    106835678 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    106835678 (NRAS)
   05161 Hepatitis B
    106835678 (NRAS)
   05160 Hepatitis C
    106835678 (NRAS)
   05163 Human cytomegalovirus infection
    106835678 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    106835678 (NRAS)
   05165 Human papillomavirus infection
    106835678 (NRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    106835678 (NRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    106835678 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    106835678 (NRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    106835678 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    106835678 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    106835678 (NRAS)
   01522 Endocrine resistance
    106835678 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:eai04131]
    106835678 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:eai04147]
    106835678 (NRAS)
   04031 GTP-binding proteins [BR:eai04031]
    106835678 (NRAS)
Membrane trafficking [BR:eai04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    106835678 (NRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    106835678 (NRAS)
Exosome [BR:eai04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   106835678 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   106835678 (NRAS)
  Exosomal proteins of breast cancer cells
   106835678 (NRAS)
  Exosomal proteins of colorectal cancer cells
   106835678 (NRAS)
GTP-binding proteins [BR:eai04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    106835678 (NRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N Septin Ldh_1_N
Other DBs
NCBI-GeneID: 106835678
NCBI-ProteinID: XP_044605475
Position
16:4885401..4895417
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG
CMGLPCVVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgactgagtacaaactggtggtggttggagcaggtggtgttggaaaaagcgcactgaca
atccagctaatccagaaccactttgtagatgaatatgatcccaccatagaggattcttac
cgaaaacaggtggttatagatggtgaaacctgtctgttggacatactggatacagctgga
caagaggagtacagtgccatgagagaccaatacatgaggacaggcgaaggcttcctctgt
gtatttgccatcaataatagcaaatcatttgcagatattaacctctacagggaacagatt
aagcgagtaaaagactcagatgatgtacctatggtgctagtaggaaacaagtgtgatttg
ccaacaaggacagttgacacaaaacaagcccatgaactggctaagagttatgggattccg
ttcatcgaaacctcagccaagaccagacagggtgttgaagatgccttttacacactggtg
agagaaatacgtcagtaccgaatgaaaaaactcaacagcagtgatgatgggactcaaggt
tgcatggggttgccgtgtgtggtgatgtaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (80)   
   KEGG PATHWAY (80)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (9)   
   Pfam (9)   
All databases (100)   

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